G01N35/00

METHOD AND DEVICE FOR QUALITY ASSESSMENT OF A PROCESSING OPERATION
20230236212 · 2023-07-27 · ·

In a method and device for assessing the quality of a processing operation, a workpiece with specific processing parameters is processed along a processing trajectory. The (X), wherein the processing result is measured by at least one sensor and at least one sensor signal is recorded and at least one quality parameter is determined based on at least one sensor signal and the at least one quality parameter is compared with quality parameter threshold values to assess the quality of the processing result. During the assessment of the processing operation quality, changes made to the processing parameters from target values during the processing are automatically taken into consideration, in that, instead of the quality parameter threshold values, quality parameter threshold values adapted to the changes in the processing parameters are determined, and the at least one quality parameter for assessing the quality of the processing result is compared with the adapted quality parameter threshold values.

Incubation Device and Automatic Analysis Device
20230236180 · 2023-07-27 ·

The disclosure relates to an incubation device and an automatic analysis device. The incubation device includes: an incubation unit (120) for incubating reaction containers (130) that contain a reactant or for buffering the cleaned and separated reaction containers (130), wherein the incubation unit (120) includes an incubation assembly (121) and an incubation driving assembly (122), the incubation driving assembly (122) is connected to the incubation assembly (121) so as to drive the incubation assembly (121) to move linearly along a third direction (30), and incubation positions (1211) for placing the reaction containers (130) are provided on the incubation assembly (121); and a transfer unit (110) for moving the reaction containers (130) into or out of the incubation unit (120), wherein the transfer unit (110) includes a pick-and-place assembly (112) and a pick-and-place driving assembly (111), the pick-and-place driving assembly (111) is connected to the pick-and-place assembly (112).

Volume Data Representation and Processing for Liquid Dispensing Devices

A system and method for ejecting one or more fluids from a digital dispense device. The method includes a) inputting to a memory a volume per unit area for each of the one or more fluids to be ejected from the digital dispense device; b) matching the volume per unit area to a device resolution for the digital dispense device; c) formatting fluid ejectors for the digital dispense device for the device resolution; and d) ejecting fluid from the digital dispense device to provide the volume per area for each of the one or more fluids.

FLUID HANDLING USING RECEPTACLE MARKING FOR NEEDLE POSITIONING
20230003752 · 2023-01-05 ·

A fluid handling unit is configured for handling a fluid contained or to be contained in a receptacle bearing a marking. The unit includes a needle having an elongated shape with an open end and for aspirating the fluid from the receptacle and/or dispensing the fluid into the receptacle. The fluid handling unit further includes a needle drive for positioning the needle with respect to the receptacle, a detection unit for detecting the marking of the receptacle, and a control unit. The control unit is configured for analyzing the detected marking for determining at least one feature that is part of the marking or the marking itself, determining a target position based on the detected at least one feature, and operating the needle drive to position the open end of the needle relative to the determined target position.

SYSTEMS AND METHODS FOR COVERSLIPPING SLIDES

Systems and methods for coverslipping a sample on a slide employ a coverslip tape. The systems and methods can reduce or eliminate the use of xylene and other toxic solvents for coverslipping.

AUTOMATIC ANALYZER
20230003755 · 2023-01-05 · ·

An automatic analyzer for analyzing samples comprising an immersion tube configured to retrieve a reagent stored in a reagent vessel and a lifting device configured to lift and lower the immersion tube. The lifting device comprises a guide rail on which the immersion tube is moveable between a lowered position, in which the immersion tube is immersed into the reagent vessel, and a lifted position, in which the immersion tube is retracted from the reagent vessel, and at least one biasing member configured to bias the immersion tube towards the lowered position with a predetermined biasing force. The analyzer further comprises a detector configured to detect an identity of the reagent, and a locking device configured to lock the immersion tube in the lifted position and so the immersion tube is moved towards the lowered position only if the reagent identity detected by the detector corresponds to a target identity.

SCHEDULING SYSTEM AND METHOD, SCHEDULING CONTROL SYSTEM, BIOCHEMICAL ANALYSIS SYSTEM AND DEVICE, AND STORAGE MEDIUM

A scheduling system includes a receiving system and a transfer system. The receiving system receives a carrier carrying a biological sample. The transfer system transfers the sample carrier between biochemical reaction platform and detection platform, so that a sample in the sample carrier performs a biochemical reaction on the biochemical reaction platform, and a signal from the reacted sample can be detected on the detection platform. The present disclosure further provides a scheduling method, a scheduling control system, a biochemical analysis system and device, and a computer-readable storage medium. The present disclosure improves a degree of automation of sample carrier scheduling, and realizes simultaneous analysis of multiple sample carriers to improve a testing throughput.

LOW-TEMPERATURE STORAGE SYSTEM
20230003754 · 2023-01-05 · ·

To provide a simple-structured low-temperature storage system capable of carrying storage objects to a full capacity on a tray and of reliably transferring storage objects without the necessity for a camera to check the positions of a rack or storage objects. The low-temperature storage system includes a storage area inside a low-temperature storage chamber for storing storage objects, and a picking area where a positioning device is disposed to allow storage objects to be carried in and out. The positioning device includes a rack fixing unit that fixes a rack, a tray fixing unit, and a drive mechanism. The rack fixing unit includes a rack pressing member that presses the rack, and a rack motion restricting member that restricts movements of the rack. The tray fixing unit includes a tray pressing member that presses the tray, and a tray motion restricting member that restricts movements of the tray.

SYSTEMS AND METHODS FOR CELL SORTING AND CELL EXTRACTION
20230002719 · 2023-01-05 ·

A cell sorter includes a base for holding a cell culture plate containing a fluorescently labeled sample of cells, a fluorescence imager for viewing the cell culture plate, through bottom of the cell culture plate, to capture one or more fluorescence images of the fluorescently labeled sample of cells, and a cell extraction module for extracting a cell selected based on the one or more fluorescence images. The cell extraction module includes a needle for hydraulically removing the selected cell from the cell culture plate, and a motorized translation stage for translating the needle in a z-dimension to reach the selected cell from above. The cell sorter further includes a motorized translation stage for translating one of the needle and the cell culture plate in x- and y-dimensions, relative to the other one of the needle and the cell culture plate, to position the needle over selected first cell.

Systems and methods for serial staining and imaging
11519832 · 2022-12-06 · ·

The present invention relates to systems and methods for sequential operation of staining, imaging and sectioning of tissue samples by a processing system. After each layer of the sample is removed by the sectioning system, the system automatically stains the exposed surface of a sample to a depth to enable imaging of the remaining tissue. The system then repeats the sectioning, staining and imaging steps in sequence to image the sample.