A sheet-shaped oral appliance is provided that is detachably attached to an oral body device and includes a functional portion with a sensor unit that acquires information in an oral cavity and an energy irradiation unit that radiates energy into the oral cavity, an electrical connection portion, and a wiring portion that connects at least one of the sensor unit and the energy irradiation unit to the electrical connection portion. The functional portion, the connection portion, and the wiring portion are formed by a wiring layer having first and second main surfaces that oppose each other, a first insulating layer arranged on the first main surface and a second insulating layer arranged on the second main surface. Moreover, in the functional portion, a thickness of the first insulating layer is smaller than a thickness of the second insulating layer.

The present invention relates to a cognitive function test server, including a communication interface, a memory; and a processor which is operably connected to the communication interface and the memory, and the processor is configured to provide a first sequence to acquire brainwave data of a user in a resting state by means of an HMD device, acquire baseline brainwave data of the user based on the first sequence, provide at least one second sequence related to a cognitive function by means of the HMD device, acquire input data and activated brainwave data based on the second sequence from the HMD device and an input device connected thereto, and generate a cognitive evaluation result of the user based on at least one of the reference brainwave data, the activated brainwave data, and the input data of the user.

A system and method for depth-resolved imaging of fluorophore concentrations in tissue uses a pulsed light source stimulus wavelength to illuminate the tissue; and a time-gated electronic camera such as a single-photon avalanche detector camera to observe the tissue in multiple time windows after start of each light pulse. A filter-changer or tunable filter is between the tissue and the electronic camera with fluorescent imaging settings and a stimulus wavelength setting, and an image processor receives reflectance images and fluorescent emissions images from the time-gated camera and processes these images into depth and quantity resolved images of fluorophore concentrations in the tissue.

Provided is a sensor device capable of detecting leakage from a pouch with a higher accuracy. An odor sensor (41) detects odor leaking from a pouch (3) attached to a stoma (21) of a user (2). A radio communication interface (42) notifies, via a notification device (5), the user (2) that odor is detected.

A vessel harvesting system removes a target vessel from a patient for use as a bypass. An elongated harvesting instrument inserts into a body along a path of a target vessel which includes at least one side branch. The harvesting instrument includes a cutter for applying thermal energy to sever and cauterize the side branch. An endoscopic camera captures visible-light images from a distal tip of the instrument within a dissected tunnel around the target vessel. A thermal camera captures thermograms coinciding with the visible-light images to characterize a temperature present at respective surfaces in the tunnel. An image processor (e.g., an electronic controller) renders a video stream including the visible-light images and an overlay depicting the temperatures present on at least some of the respective surfaces when applying the thermal energy. A display presenting the video stream and overlay to a user can be an augmented-reality display.

In one embodiment, an ablation system includes a catheter including at least one electrode, and configured to be inserted into a chamber of a heart of a living subject, an ablation power generator configured to apply an electrical signal to the at least one electrode to ablate tissue of the chamber, at least one body surface patch configured to be applied to a body surface of the living subject, and provide at least one position signal, and a processor configured to compute an index of a measurement of diaphragm movement responsively to the at least one position signal, and perform an action responsively to the computed index.

This disclosure is directed to systems and techniques for detecting change in patient health and if a change in patient health is detected, direct a medical device to generate for display output indicating the detection of the change in patient health. An example medical system or technique applies a model to values of configurable settings that are programmed into detection logic of a medical device; based on the application, determine whether modified values of the configurable settings, when implemented by the detection logic, would change a determination, by the medical device, regarding whether sensed physiological activity is indicative of cardiac episode for a patient; and in response to a determination that the modified values would change the determination regarding whether the sensed physiological activity is indicative of the cardiac episode for the patient, generate output data indicative of the modified values for the configurable settings for the medical device.

The present invention provides a photodiode for a wearable sensor system, the photodiode having a rectangular active area sensitive to wavelengths within the spectral range of 1200 nm to 2400 nm. The present invention also provides a wearable sensor system comprising the photodiode.

The present invention relates to a fixation and body temperature maintaining apparatus for fixing a small animal in order to generate a high-resolution micro image of a predetermined tissue of the small animal within a biomicroscope with an object lens, which includes: a plate heater with a heat wire installed therein, on which the small animal is enabled to be directly placed; a glass heater holder fixed to a hole of the plate heater; and a glass heater fixed to the glass heater holder, and located above the tissue of the small animal and maintaining flatness of the tissue, and increasing a temperature of the tissue itself, in which a cover glass serving to adjust a refractive index of the object lens and a heat wire heater are integrally formed. In an embodiment of the present invention, a body temperature of a live small animal which is an object to be observed with a biomicroscope is maintained to be constant.

Systems and methods are provided for non-invasive measurement of endogenous S-nitrosothiols and related measurements thereof. One or more sensors non-invasively measures a set of one or more biometric parameters within a region of interest of a subject to provide a time series of measurements for each of the set of biometric parameters. A medium stores machine-readable instructions that are executable by an associated processor to perform processing comprising receiving the time series of measurements of the biometric parameter, generating, using a predictive model, a value representing an endogenous S-nitrosothiol content of tissue within the region of interest from the time series of measurements of the biometric parameter, and providing, by a user interface, the value representing the endogenous S-nitrosothiol content of tissue within the region of interest to a user.