An olfaction test device (1) causes air flowing into an inflow path (120) by use of a compressor (121) to have a constant flow velocity and a constant flow rate by passing the air through a sonic nozzle (124). The air is caused to pass through an opened one of inflow valves (126 to 129) disposed in branches of the inflow path (120) and to flow into any one of sample containers (101 to 104), whereby gases with different smell intensities are generated. The gases are then warmed by a heater (153) disposed in an outflow path (150) and released in a nose mask (155).

A device and manufacturing method for a surgical navigation system, comprising a frame member having an attachment location and a rigid mounting device disposed in the attachment location. The frame member comprises an upper straight portion connected to a lower straight portion via a bent portion, wherein the lower straight portion comprises a plurality of mounts each having a top surface. A centerline extending through the rigid mounting device is level with each of the top surfaces.

A bone screw includes a main body having a proximal end and a distal end. The main body extends along a longitudinal axis. The main body has an externally threaded surface that includes at least one helically extending thread having a minor diameter and a major diameter, which major diameter is greater than the minor diameter. The thread includes at least two flank surfaces extending between the minor diameter and the major diameter. The minor diameter of the thread defines a central portion of the main body. The thread may include at least one aperture that extends along an aperture axis through the thread between the flank surfaces.

A gauge assembly includes a distal femur gauge including medial and lateral condyle paddles each having a shape and size corresponding to a pre-operative planned distal resection of a patient's femur, and a tibial cutting block connected to the distal femur gauge. The condyle paddles include features, for example, pin-receiving holes, that permit intra-operative anterior-posterior and/or internal-external adjustment of the position of the distal femur gauge. The tibial cutting block includes features, for example, pin-receiving slot and holes, that permit fixing of the varus-valgus and flexion-extension degrees of freedom prior to fixing the internal-external and medial-lateral degrees of freedom.

A cutting instrument includes a cutting wedge. The cutting wedge can include a leading edge and one or more cutting fasciae terminating at the leading edge. The one or more cutting fasciae can include an approximately concave recess. Other embodiments are disclosed.

A catheter includes an insertion tube, a flexible substrate and one or more electrical devices. The insertion tube is configured for insertion into a patient body. The flexible substrate is configured to wrap around a distal end of the insertion tube and includes electrical interconnections. The electrical devices are coupled to the flexible substrate and are connected to the electrical interconnections.

Embodiments provide methods, apparatuses, and systems for fixation of a fractured bone. In various embodiments, the systems and plates may provide elastic suspension of the receiving holes relative to the osteosynthesis plate. This elastic suspension may promote load distribution between the screws that connect a bone segment to the plate, thereby reducing stress risers and load shielding effect, In addition, stress at the screw holes, and within the construct as a whole, is reduced by incorporation of these elastic elements in the plate. Additionally, in some embodiments, for instance if fracture healing by callus formation is desired, elastic suspension of the receiving holes relative to the osteosynthesis plate may enable small, controlled amounts of relative motion between bone fragments connected by the plate, which may promote fracture healing by callus formation.

A catheter includes an insertion tube, a flexible substrate and one or more electrical devices. The insertion tube is configured for insertion into a patient body. The flexible substrate is configured to wrap around a distal end of the insertion tube and includes electrical interconnections. The electrical devices are coupled to the flexible substrate and are connected to the electrical interconnections.

Pen-type lancing device of the re-usable type wherein a lancet body having a needle/tip is inserted; standard spring type actuator (urging member); skin touching forward face having a textured surface for pain relieve; sleeve having internal stop(s) so that the lancet does not overshoot. Also a pen-type lancing device of the re-usable type wherein a lancet body having a needle/tip is inserted; elastomer type urging member for driving the lancet; triggering means (denoted actuating means). Further a pen-type lancing device of the reusable type wherein a lancet body having a needle/tip is inserted; standard spring type actuator (urging member) for driving the lancet; alignment splines and cooperating alignment portion(s) for guiding the lancet movement. Even further a method of assembling a blood sampling device in which it does not matter what rotational orientation the components are assembled in.

An apparatus for estimating a concentration of a biomarker, may include: an inlet configured to receive the biomarker of an object; a chamber configured to store the biomarker; a sensor cartridge comprising a measurement channel provided as a porous substrate, the measurement channel comprising a probe which is disposed in each pore of the porous substrate and changes in color upon reaction with the biomarker; a light source configured to emit light onto the measurement channel; a detector configured to detect the light incident from the measurement channel; and a processor configured to obtain color change information of the measurement channel based on the light detected by the detector, and estimate the concentration of the biomarker based on the color change information.