A system for facilitating resuscitation includes: a first electrode assembly having a therapy side and a first motion sensor; a second electrode assembly having a therapy side and a second motion sensor; processing circuitry operatively connected to and programmed to receive and process signals from the first and second motion sensors to estimate at least one of a chest compression depth and rate during administration of chest compressions and to compare the chest compression depth or rate to a desired range; and an output device for providing instructions to a user to administer chest compressions based on the comparison of the estimated chest compression depth or rate to the desired range. One or both of the electrode assemblies may be constructed so that the conductive therapeutic portion is able to maintain substantial conformance to the anatomy of the patient when coupled thereto. For example, at least a portion of the flexible electrode pad may be able to flex from a more rigid sensor housing, or the sensor housing itself may be relatively small compared to the flexible electrode pad so as not to cause lift off of the therapeutic side from the patient.

The sensor includes a working electrode having a first wire with a first flat surface and an electrochemical element on the first flat surface. A reference electrode includes a second wire with a second flat surface and a counter electrode includes a third wire with a third flat surface. The first wire is a first sensor wire for the working electrode, the second wire is a second sensor wire for the reference electrode and the third wire is a third sensor wire for the counter electrode in a plurality of sensor wires. The second flat surface and the third flat surface face toward each other.

An apparatus includes a body and an actuator is coupled to the body. A needle is mounted to the actuator. The needle comprises a slot along a length to a tip. A sensor is coupled to a plurality of wires. A base is configured to be moveable by the actuator and includes a cutout, a circuit board having a microprocessor, and a plurality of contacts. Each contact is coupled to a wire of the plurality of wires. A power source is connected to the circuit board and to the base. A bracket is coupled to the bottom surface of the body and configured to receive the base. A patch is coupled to the bracket and has an adhesive. A needle is configured to be moveable by the actuator. The plurality of wires extend from the circuit board of the base, through the needle and out of the slot.

A photoplethysmographic (PPG) signal communicated by a PPG sensor of a wearable device worn by a user may be received by a processor. The processor may detect a plurality of heartbeats of the user from the PPG-signal, determine a heart rate of the user based on at least the plurality of heartbeats, determine a heart rate variability (HRV) based on the plurality of heartbeats, determine a respiration rate of the user based on a low frequency component of the PPG signal, and determine whether the user is in a stressed state based on the heart rate, the HRV, and the respiration rate. The processor may cause the display of information related to the stress state of the user, and instructions and/or advice for reducing a stress level of the user.

A system for facilitating resuscitation includes: a first electrode assembly having a therapy side and a first motion sensor; a second electrode assembly having a therapy side and a second motion sensor; processing circuitry operatively connected to and programmed to receive and process signals from the first and second motion sensors to estimate at least one of a chest compression depth and rate during administration of chest compressions and to compare the chest compression depth or rate to a desired range; and an output device for providing instructions to a user to administer chest compressions based on the comparison of the estimated chest compression depth or rate to the desired range. One or both of the electrode assemblies may be constructed so that the conductive therapeutic portion is able to maintain substantial conformance to the anatomy of the patient when coupled thereto. For example, at least a portion of the flexible electrode pad may be able to flex from a more rigid sensor housing, or the sensor housing itself may be relatively small compared to the flexible electrode pad so as not to cause lift off of the therapeutic side from the patient.

Disclosed herein are nanoscale field effect transistors (NFETs), e.g., graphene based field effect transistors (GFETs), that do not have physical gates. Instead, they are gated by polar fluids. Systems and methods using such transistors are also disclosed.

On-body analyte sensors may be designed for extended wear to provide ongoing measurement of physiological analyte levels. However, on-body analyte sensors may be susceptible to damage or dislodgment during wear due to routine interactions that occur with one's surroundings. Guard rings may be adapted to protect on-body analyte sensors from such interactions. Guard rings may comprise an annular body comprising an inner perimeter face, an outer perimeter face, a top edge, and a bottom face adapted for contacting a tissue surface. The inner perimeter face is shaped to circumferentially surround a sensor housing of an on-body analyte sensor. At least a portion of the outer perimeter face defines a chamfered surface extending between the top face and the bottom face. Adhesive pads or strips may further be engaged with the guard rings and aid in securing the guard rings to a surface, such as skin.

A system comprises a teleoperated manipulator, a manually operated instrument, and a position sensor coupled to the manually operated instrument. The position sensor is configured to generate pose information for the manually operated instrument. The system further comprises a controller configured to map a pose of the manipulator to a fixed world reference frame based on three-dimensional pose information for the manipulator known internally within the system. The controller is further configured to map a pose of the manually operated instrument to the fixed world reference frame based on the pose information for the manually operated instrument.

A non-invasive epidermal electrochemical sensor device includes an adhesive membrane; a flexible or stretchable substrate disposed over the adhesive membrane; and an anodic electrode assembly disposed over the flexible or stretchable substrate including an iontophoretic electrode. The device includes a cathodic electrode assembly disposed adjacent to the anodic electrode assembly over the flexible or stretchable substrate and includes an iontophoretic electrode. Either the cathodic electrode assembly or the anodic electrode assembly also includes a sensing electrode that includes a working electrode and at least one of a counter electrode or a reference electrode. The iontophoretic electrode in either the anodic electrode assembly or the cathodic electrode assembly that includes the sensing electrode is disposed on the substrate to at least partially encompass the working electrode and the at least one of the counter electrode or the reference electrode. The device includes an electrode interface assembly including independent electrically conductive contacts.

According to one aspect of the present disclosure, a surgical instrument is disclosed. The instrument includes a handle portion, a body portion extending distally from the handle portion and defining a first longitudinal axis and a loading unit. The loading unit includes a tool assembly, the loading adapted to be coupled to the body portion. The instrument also includes a sensor tube movably positioned within the body portion, the sensor tube adapted to engage the loading unit and a load switch coupled to a microcontroller. The load switch is adapted to be actuated by the sensor tube when the sensor tube is engaged by the loading unit being inserted into the body portion.