A restrainer system for performing awake-animal imaging on a rodent. The system comprises a front section, a first pair of adjustable side pieces for contacting with a snout of the rodent from both sides, a second pair of adjustable side pieces for contacting with a rear jaw of the rodent from both sides, a front section, first floating component for applying pressure to a nose section of the rodent during testing and a mouthpiece for holding the rodent's teeth. That front section connects to a middle section having a floor element upon which to rest a main body of the rodent and all four limbs, a pair of adjustable walls for applying pressure to the rodent's back legs, and a middle section floating component for applying pressure to the rodent's shoulder blades from above. The latter connects to a rear section having a plateau onto which to rest the rodent's tail, and a rear section floating component for securing over the rodent's tail. A method of use is also disclosed.

An animal restraint for dogs that maintains four points of contact to safely, securely, and humanely restrain the dog. The system includes a platform and four poles that can support the animal. The forward poles support a cross shoulder bar which prevents the dog's forward from rising. A belly strap or bar may be used under the belly of the animal to prevent the rear or bending of hind legs. An optional over strap may be used to loop around the animal's rear. The animal's leash may be mounted to the device, preferably at the top and center of the shoulder bar. The device may be adjustable in height and rotation of the poles. The system may be collapsible to allow for storage.

A treatment assembly can have an inner layer having an inner surface and an outer surface and defining a plurality of openings extending therethrough. The treatment assembly can further comprise a plurality of plates, each plate being at least partially received within a respective opening of the plurality of openings of the inner layer. The treatment assembly can further comprise treatment circuitry comprising a cable having a plurality of electrical leads and a plurality of lead ends, each electrical lead being electrically connected to a respective lead end of the plurality of lead ends. A cover layer can be attached to the outer surface of the inner layer and overlie the plurality of lead ends of the cable. The plurality of lead ends can be in contact with respective plates of the plurality of plates to define a plurality of electrodes.

Devices and systems are disclosed which reduce compressional forces and allows for the induction of mild CCI injuries. An exemplary device features a resettable fall-away platform which allows for ultra-mild injuries to be induced on mice that are under light anesthesia. The result is injuries which do not produce long periods of unconsciousness, do not cause compressive injury and cause no increase in time-to-righting over control mice.

Devices and systems are disclosed which reduce compressional forces and allows for the induction of mild CCI injuries. An exemplary device features a resettable fall-away platform which allows for ultra-mild injuries to be induced on mice that are under light anesthesia. The result is injuries which do not produce long periods of unconsciousness, do not cause compressive injury and cause no increase in time-to-righting over control mice.

A restraining device for an animal. A body having a base and two spaced-apart walls define a cavity to receive the animal. At least one pair of side restraining members is mounted to one of the walls of the body. Each restraining member is displaceable away from the wall and into the cavity to engage a side of the animal. An overhead restraining member is mounted to the body above the base. The overhead restraining member is displaceable toward and away from the base to engage the animal. A tightening mechanism is mounted to the body and has at least one rotatable rod. The first end of the rod has a rotatable handle to rotate the rod and the second end has a cam engaging one of the side restraining members. The handle rotates the cam and displaces the side restraining members into the cavity.

A restraining device for an animal. A body having a base and two spaced-apart walls define a cavity to receive the animal. At least one pair of side restraining members is mounted to one of the walls of the body. Each restraining member is displaceable away from the wall and into the cavity to engage a side of the animal. An overhead restraining member is mounted to the body above the base. The overhead restraining member is displaceable toward and away from the base to engage the animal. A tightening mechanism is mounted to the body and has at least one rotatable rod. The first end of the rod has a rotatable handle to rotate the rod and the second end has a cam engaging one of the side restraining members. The handle rotates the cam and displaces the side restraining members into the cavity.

A system and method for automatically delivering a substance to an animal including a positioning system that positions each animal singularly, a sensor that detects the location of a predetermined targeted area on the animal and an image processor. The system further includes a delivery device having a plurality of delivery outlets for delivering a substance to the targeted area. The sensor, image processor and delivery device are in communication with a computer processor. The sensor activates the image processor which takes at least one image of the animal positioned singularly. The image is communicated to the computer processor and analyzed. The computer processor activates the delivery outlet proximate the predetermined target area on the animal which delivers an effective dosage of substance to the predetermined targeted area.

A system and method for automatically delivering a substance to an animal including a positioning system that positions each animal singularly, a sensor that detects the location of a predetermined targeted area on the animal and an image processor. The system further includes a delivery device having a plurality of delivery outlets for delivering a substance to the targeted area. The sensor, image processor and delivery device are in communication with a computer processor. The sensor activates the image processor which takes at least one image of the animal positioned singularly. The image is communicated to the computer processor and analyzed. The computer processor activates the delivery outlet proximate the predetermined target area on the animal which delivers an effective dosage of substance to the predetermined targeted area.

An animal supporting device having a having three primary dimensions of unequal lengths for engaging the abdomen or other body part of an animal at various support elevations. The device may have one or more trough-shaped channels for engaging the abdomen or other body part of the animal at alternative support elevations. The device may have a dog-bone-shaped outline. Other embodiments are described and shown.