A ring-shaped cushion for a hearing protector or audio headset. The cushion has a circumferential contact pad for sealing on a wearer's head and an attachment for sealing with an earmuff. The cushion further has a sound insulation tube that inwardly defines an inner space. The sound insulation tube extends between the contact pad and the attachment. The cushion has a ventilation passage that extends entirely through the cushion between an inlet opening in the contact pad and an area outside of the inner space. The cushion may further include one or more physiological sensors to monitor the health of a wearer.

Methods are provided to make a prosthetic valve having a thin, biocompatible, high-strength, composite material. In one aspect, the composite material maintains flexibility in high-cycle flexural applications, making it particularly applicable to high-flex implants such as a heart valve leaflet. The composite material includes a porous expanded fluoropolymer membrane and an elastomer, wherein the elastomer is present in the pores of the porous expanded fluoropolymer.

Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.

Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.

Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.

Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.

A ring-shaped cushion for a hearing protector or audio headset. The cushion has a circumferential contact pad for sealing on a wearer's head and an attachment for sealing with an earmuff. The cushion further has a sound insulation tube that inwardly defines an inner space. The sound insulation tube extends between the contact pad and the attachment. The cushion has a ventilation passage that extends entirely through the cushion between an inlet opening in the contact pad and an area outside of the inner space. The cushion may further include one or more physiological sensors to monitor the health of a wearer.

Described embodiments are directed toward prosthetic valves having leaflets of a particular shape that improves bending character without requiring a long length valve. In accordance with an embodiment, a prosthetic valve comprises a leaflet frame, a plurality of leaflets that are coupled to the leaflet frame, where each leaflet has a free edge and a base. The base of each leaflet is truncated in which the leaflet in cross section shows a line in an alpha plane onto the leaflet frame.

Described embodiments are directed toward prosthetic valves having leaflets of a particular shape that improves bending character without requiring a long length valve. In accordance with an embodiment, a prosthetic valve comprises a leaflet frame, a plurality of leaflets that are coupled to the leaflet frame, where each leaflet has a free edge and a base. The base of each leaflet is truncated in which the leaflet in cross section shows a line in an alpha plane onto the leaflet frame.

A prosthetic heart valve can include a frame defining a central longitudinal axis and a plurality of leaflets. Each leaflet can include: a leaflet free edge, a first leaflet side forming a first leaflet side line of attachment along the frame, a second leaflet side forming a second leaflet side line of attachment along the frame, and a leaflet base forming a leaflet base line of attachment along the frame from an end of the first leaflet side line of attachment to an end of the second leaflet side line of attachment. The first leaflet side line of attachment can form a continuous attachment of the first leaflet side to the frame along an entire extent of the first leaflet side. The second leaflet side line of attachment can form a continuous attachment of the second leaflet side to the frame along an entire extent of the second leaflet side.