Provided herein are methods and compositions related to bacteria of genus Rothia useful as therapeutic agents for dental caries.

The present disclosure relates to a dental ceramic article comprising ceramic components, the ceramic components having ZrO2 and Al2O3 and at least one component comprising Mn, Er or mixtures thereof, Al2O3 being present in an amount below about 0.15 wt.-% with respect to the weight of the ceramic article. The present disclosure relates also to kit of parts comprising a ceramic article and a coloring solution and processes for producing a dental ceramic article.

The invention provides compositions and methods for treatment of Alzheimer's disease. Such methods entail administering agents that induce a beneficial immune and therapeutic response against an amyloid deposit in the patient. The methods are particularly useful for prophylactic and therapeutic treatment of Alzheimer's disease. In certain preferred embodiments of such methods, a preferred agent is amyloid beta peptide in combination with Sphingosine-1-phosphate, preferably delivered in certain embodiments in a liposomal formulation.

The invention relates to a solution for coloring and imparting fluorescence to a zirconia dental article, the solution comprising: •a solvent, •a coloring agent comprising ions selected from Tb, Er, Pr, Mn and combinations thereof, •a fluorescing agent comprising ions of Bi, the solution not comprising Fe ions in an amount above about 0.05 wt.-% with respect to the weight of the whole solution.

Pre-sintered blanks based on lithium metasilicate glass ceramic are described which are suitable in particular for the preparation of dental restorations.

A dental implant unit includes a layer of synthetically created titanium dioxide. The dental implant unit has one end for connection and a lateral surface covering the implant unit except for the end for connection. The lateral surface includes a layer of synthetically created titanium dioxide while the end for connection is free from synthetically created titanium dioxide. Also, a method produces a whitened implantable dental unit. The method includes thermal oxidation of a dental implant unit that includes titanium.

A Addition-fragmentation oligomers containing allylic disulfide groups are described. The oligomers may be added to polymerizable compositions to provide labile crosslinks that can cleave and reform during the polymerization process.

Described are compositions and methods for the removal of zinc-oxide eugenol-based temporary cements or root canal filling materials from a variety of surfaces including surfaces inside the oral cavity, such as teeth, as well as surfaces of objects located outside of the oral cavity, such as instruments and prostheses. In certain compositions, the resin-dentin bond between permanent cements and collagen-containing surfaces can be increased. The compositions are non-toxic, can be used inside the oral cavity, and do not require special disposal procedures.

The present invention relates to the deposition of a micro-crystalline hydroxyapatite and tricalcium phosphate coating onto gutta-percha cones, to be used as dental composite for root canal filling. The method proposed for coating involves the surface pretreatment of gutta-percha cones with sodium hydroxide; immersion of gutta-percha cones in simulated body fluid, which contains calcium and phosphate ions; and replacing consumed simulated body fluid after an interval of time, at physiological pH and temperature. The nucleation process results in the biomimetic deposition of a thin and uniform layer of calcium phosphates and hydroxyapatite. Improved characteristics such as in sealing ability, bonding strength, and ability to form hermetic seal, therefore allows the dental composite produced, to be used appropriately as filling matter in root canal treatments.

Oral care compositions with silica particles and stannous fluoride with an improved tin compatibility are disclosed. Oral care compositions with silica particles and stannous fluoride with a low level of an additional tin compound are disclosed. Oral care compositions with substantially spherical silica particles are disclosed.