The present invention is related to the inhibition of the formation of Streptococci biofilms through the inhibition of glucosyl transferase (Gtf). Compounds, compositions and methods for inhibiting Streptococcus biofilm formation, as well as for preventing, inhibiting and/or treating the formation of dental caries, and methods of identifying compounds that prevent, inhibit and/or treat the formation of dental caries are provided.

The present invention is related to the inhibition of the formation of Streptococci biofilms through the inhibition of glucosyl transferase (Gtf). Compounds, compositions and methods for inhibiting Streptococcus biofilm formation, as well as for preventing, inhibiting and/or treating the formation of dental caries, and methods of identifying compounds that prevent, inhibit and/or treat the formation of dental caries are provided.

A novel hydrogel wound dressing therapy and methods for making the same. The novel methods comprise forming two biopolymers, chitosan and hyaluronic acid, together into a wound dressing with inherent ability to enhance wound closure. The novel composition of the subject invention comprises cross-linked chitosan/hyaluronic acid hydrogels manufactured according to the methods disclosed having a specific cross-link density that results in a swelling ratio of 20 to 100. Hydrogels manufactured in accordance with the method of the invention dramatically increase healing rates and greatly improves outcomes of wound injuries.

Described herein are block copolymers having hydrophobic blocks and hydrophilic blocks which are effective in binding to the surface of hard tissue; compositions comprising the same, as well as methods of making and using the same.

A dental device that provides for the entirely non-surgical management of early, cavitated dental lesions consisting of a ceramic wafer sized to cover the dental lesion and resin bonded to the tooth effectively encapsulating the dental lesion. The ceramic wafer may incorporate antimicrobial preparations, radiopaque markers, and/or silver diamine fluoride.

The invention relates to the application of a composition containing recombinant amelogenin and propylene glycol alginate (PGA) on to cut dentin tubules followed by installation of a definitive restorative in a single visit.

The present invention is directed to a composition of temporary crown materials, comprising a powder reagent and a liquid reagent; wherein the powder reagent comprises PMMA and an initiator, and the liquid reagent comprises MMA, a catalyst, and a plasticizer; wherein the plasticizer is a citrate ester compound. The composition of temporary crown materials of the present invention has high hardness, high toughness, high flexural strength and excellent biocompatibility.

Provided are methods and compositions relating to a dental composition more specifically to prepare the damaged dentin of the tooth prior to repair. The dental compositions include a bioactive glass and a non-aqueous solvent comprising an alcohol, anti-inflammatory and anti-pain reliver.

Adhesive for dental prostheses consists of pharmaceutical glycerin 99.5% in the amount of 29-31 wt %, monopropylene glycol in the amount of 27-29 wt %, purified water in the amount of 22-24 wt %, polyvinylpyrrolidone with a mean molar mass of 360,000 in the amount of 14-16 wt %, carboxymethylcellulose in the amount of 1-3 wt %, dried grapefruit pomace extract in a water-glycerin solvent, containing not less than 1200 mg of naringin per 100 mL of extract in the amount of 0.5-2 wt %, menthol in the amount of 0.05-0.15 wt % and benzalkonium chloride in the amount of 0.01-0.03 wt %.

The present invention is related to the inhibition of the formation of Streptococci biofilms through the inhibition of glucosyl transferase (Gtf). Compounds, compositions and methods for inhibiting Streptococcus biofilm formation, as well as for preventing, inhibiting and/or treating the formation of dental caries, and methods of identifying compounds that prevent, inhibit and/or treat the formation of dental caries are provided.