Disclosed are water-based personal cleansing compositions having an isotropic surfactant phase, the compositions containing (a) cationic surfactant that includes a quaternary ammonium compound and/or an amidoamine, (b) cleansing surfactant and (c) water, the cleansing surfactant containing 85 to 100% by weight of a combination of betaine surfactant and taurate surfactant in particular ratios; also disclosed are methods of thickening such compositions by the addition of electrolyte.

The present invention provides a liposomal topical formulation or a liposomal topical formulation base having barrier-forming siliconic components, methods for making the same, and methods for using the same in the treatment of dermatological diseases and conditions, including male pattern baldness.

A method for preparing a cosmetic kit provides cosmetics which are customized (personalized) for each user and a cosmetic provision device which uses the kit to supply customized cosmetics. The cosmetic kit includes a plurality of cosmetic bases, and is used for customized cosmetics which are prepared by mixing the plurality of cosmetic bases in accordance with recipe information determined on the basis of user unique information. The method provides a cosmetic kit with a container containing at least two cosmetic bases selected from the plurality of cosmetic bases that is rotated at a prescribed speed, and a new-infrared measurement of the bases in the container is performed at prescribed time intervals, the time (T)required to obtain an nth measurement, in which the rate of change between the absorbance in the nth measurement and the absorbance in the previous ((n−1)th)measurement is 100%±5%, and the rate of change with respect to the absorbance in the following ((n+1)th) measurement is 100%±5%. is not more than 35 minutes.

A method for preparing a cosmetic kit provides cosmetics which are customized (personalized) for each user and a cosmetic provision device which uses the kit to supply customized cosmetics. The cosmetic kit includes a plurality of cosmetic bases, and is used for customized cosmetics which are prepared by mixing the plurality of cosmetic bases in accordance with recipe information determined on the basis of user unique information. The method provides a cosmetic kit with a container containing at least two cosmetic bases selected from the plurality of cosmetic bases that is rotated at a prescribed speed, and a new-infrared measurement of the bases in the container is performed at prescribed time intervals, the time (T)required to obtain an nth measurement, in which the rate of change between the absorbance in the nth measurement and the absorbance in the previous ((n−1)th)measurement is 100%±5%, and the rate of change with respect to the absorbance in the following ((n+1)th) measurement is 100%±5%. is not more than 35 minutes.

An implantable medical device is provided. The core includes a core polymer matrix within which is dispersed a therapeutic agent comprising one or more aromatase inhibitors. The core polymer matrix contains an ethylene vinyl acetate copolymer. The ethylene vinyl acetate copolymer has a melting temperature of from about 40° C. to about 120° C. as determined in accordance with ASTM D3418-15.

A system is provided enabling do it yourself body stencilling and/or body art. In particular, the system of the invention provides a body tight removable mask that masks an area of the body for body painting. The mask is sized to fit a particular portion of the torso or an appendage of a subject individual, and masks a standard area to enable an unskilled artist to paint a portion of the subject individual. The stencil can mask a logo of a sports team or other form such as a swimsuit form on a wrist or ankle or upper torso, forehead, or a bathing suit area of the subject individual. The system optionally includes adhesive, Velcro, or other interlocking overlapping portions enabling easy removal of the stencil without disturbing the freshly painted area. In its simplest form, the stencil is a mask of the thighs, and the waste, the lower chest area and upper chest area, for example, with a preferably elastic mask panel that can be easily removed once the basic painting is complete. Advantageously, the invention enables websites that feature body painting, such as Sports teams, Universities, Sports Illustrated or Fashion TV, to sell stencil product in association with displays of body painted models.

Systems and methods for generating user-specific recommendations of products or services by collaborative filtering executed and/or performed by one or more trained or untrained predictive models configured to ingest product attribute(s), product purpose(s), user location data, and/or user demographics. The predictive model(s) are leveraged to detect and determine user-specific preferences for, and preferences against, particular attributes, features, ingredients, aesthetic styles, and so on.

Systems and methods for generating user-specific recommendations of products or services by collaborative filtering executed and/or performed by one or more trained or untrained predictive models configured to ingest product attribute(s), product purpose(s), user location data, and/or user demographics. The predictive model(s) are leveraged to detect and determine user-specific preferences for, and preferences against, particular attributes, features, ingredients, aesthetic styles, and so on.

The invention relates to stable liquid neurotoxin formulations which are free of animal proteins, comprising a surfactant, an amino acid selected from tryptophan and tyrosine, a buffer comprising sodium, chloride and phosphate ions, which have a pH between 5.5 and 8, and which are stable for 2 months. These compositions are suitable for use in therapy and in particular for administration to a patient to achieve a desired therapeutic or aesthetic effect. The invention also relates to the use of an amino acid selected from tryptophan and tyrosine to protect a proteinaceous neurotoxin from degradation in a liquid composition which is free of animal derived proteins.

The invention relates to stable liquid neurotoxin formulations which are free of animal proteins, comprising a surfactant, an amino acid selected from tryptophan and tyrosine, a buffer comprising sodium, chloride and phosphate ions, which have a pH between 5.5 and 8, and which are stable for 2 months. These compositions are suitable for use in therapy and in particular for administration to a patient to achieve a desired therapeutic or aesthetic effect. The invention also relates to the use of an amino acid selected from tryptophan and tyrosine to protect a proteinaceous neurotoxin from degradation in a liquid composition which is free of animal derived proteins.