The invention relates, in part, to devices, systems and methods to increase the likelihood of survival and reproductive success of preselected organisms.

The invention relates, in part, to devices, systems and methods to increase the likelihood of survival and reproductive success of preselected organisms.

Methods, compositions and systems are presented to deliver estradiol benzoate to an animal so as to sterilize the animal.

Methods, compositions and systems are presented to deliver estradiol benzoate to an animal so as to sterilize the animal.

Methods, compositions and systems are presented to deliver estradiol benzoate to prevent and/or inhibit boar taint and/or male aggression as compared to animal that has not been administered estradiol.

Methods, compositions and systems are presented to deliver estradiol benzoate to prevent and/or inhibit boar taint and/or male aggression as compared to animal that has not been administered estradiol.

An apparatus and methods for detection of estrus and optimal time for embryo transfer or artificial insemination in animals. An arched polycarbonate housing is attached to an animal. A circuit board is disposed within the housing. A rechargeable battery mounted on the circuit board provides power to the apparatus. A switch mounted on the circuit board is actuated when a breeding behavior occurs. A controller mounted on the circuit board detects actuations of the switch to generate data indicative of breeding behavior. A transmitter transmits data indicative of breeding behavior to a remote receiver.

An apparatus and methods for detection of estrus and optimal time for embryo transfer or artificial insemination in animals. An arched polycarbonate housing is attached to an animal. A circuit board is disposed within the housing. A rechargeable battery mounted on the circuit board provides power to the apparatus. A switch mounted on the circuit board is actuated when a breeding behavior occurs. A controller mounted on the circuit board detects actuations of the switch to generate data indicative of breeding behavior. A transmitter transmits data indicative of breeding behavior to a remote receiver.

A protective apparatus covers the male genitalia of an animal, for example a dog. The apparatus includes a harness arrangement securable about a torso of the animal and a cage supported by the harness arrangement to at least partially surround the male genitalia of the animal when the harness arrangement is worn about the torso of the animal. The cage is resilient and self-supporting in shape, while including one or more openings therein sized to allow passage of bodily fluids therethrough. The apparatus prevents copulation and/or prevents animal access to wounds resulting from neutering of the animal. The self-supporting material of the cage ensures that the cage is supported in spaced apart relation with the male genitalia so that urine is less likely to be directed onto the belly of the animal during urination, while still remaining comfortable for the animal due to its resilient collapsibility.

A method for non-surgical neutering or castration of a non-human mammal for AAV-mediated delivery of an anti-GnRH polypeptide to a non-human animal is described. More particularly, the animal is administered an adeno-associated virus (AAV) vector having an AAV capsid having packaged therein nucleic acid sequences comprising an AAV 5′ inverted terminal repeat (ITR), a sequence encoding a polypeptide which specifically binds gonadotropin releasing hormone (GnRH) under control of regulatory sequences which direct expression of the polypeptide, and an AAV 3′ ITR. A composition comprising the AAV-anti-GnRH may also be used for inhibiting tumor growth in a mammal with a cancer responsive to gonadal steroid hormones.