The present disclosure relates to compositions and methods of killing cells. In particular examples, the method includes contacting a cell having a cell surface protein with a therapeutically effective amount of an antibody-IR700 molecule, wherein the antibody specifically binds to the cell surface protein, such as a tumor-specific antigen on the surface of a tumor cell. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm at a dose of at least 1 J cm.sup.−2. The cell is also contacted with one or more therapeutic agents (such as an anti-cancer agent), for example about 0 to 8 hours after irradiating the cell, thereby killing the cell. Also provided are methods of imaging cell killing in real time, using fluorescence lifetime imaging. Also provided are wearable devices that include an article of clothing, jewelry, or covering; and an NIR LED incorporated into the article, which can be used with the disclosed methods.

Systems, methods, and devices for producing appliances for expansion of the arch of a patient are provided. An arch expanding appliance comprises a force generating portion to apply an arch expansion force and a retention portion to hold the force generating portion on the teeth. The retention portion comprises a flexible portion and a stiff portion. The force generating portion applies a force to move teeth associated with the flexible portion, while the stiff portion resists movement of its associated teeth. The orthodontic appliances can be designed according to the specifications provided herein and manufactured using direct fabrication methods.

Functional jewelry is disclosed. A bracelet includes a plurality of light-emitting diodes (LEDs), a main control unit, and positional and situational sensors, typically including an accelerometer, as well as a decorative, interchangeable fascial layer. The bracelet may also include sensors such as capacitive touch sensors, a microphone, and a color sensor. A radio transceiver within the bracelet is adapted to implement a protocol such as BLUETOOTH® 4.0, and is adapted to allow the bracelet to communicate in peer-to-peer or master-slave mode. Two users can pair their bracelets in person, usually with a gestural trigger, for shared light displays, multi-player games, and other types of interactions. Larger groups can pair temporarily and contextually for multi-user displays and interactions, in an ad hoc network with distributed functions. Real-world interactions are communicated to a social network with profiles linked to the individual bracelets.

Disclosed is a luminous necklace structure. The present invention adopts the following technical solution: a luminous necklace structure, comprising a battery case; a chain rope with both ends connected with the battery case; pendant(s), at least one of which is connected with the chain rope, so that the battery case can supply power to the chain rope and make the pendant(s) luminous. The beneficial effects of the present invention are as follows: the chain rope and the light shade adopt diversified connecting methods which are more flexible and convenient for use, the movable connection between the light holder and the light shade makes the luminophor changeable, thus prolonging the service life of the luminous necklace and meanwhile saving the costs, and the same luminous necklace is allowed to be provided with either luminous or non-luminous light shade, thus enhancing the luminous effect of the necklace.

The invention relates to a cemented carbide composition producing method for precious metal, which includes a titanium nitride component contained therein and shows excellent workability, corrosion resistance, reduction in weight and other desirable mechanical properties, as well as the low amount of nickel used as a metallic binder and an aluminum oxide coating helps to suppress potential negative skin reactions.

A wearable aroma emitting device housing a refillable, removable atomizer spray bottle. The device comprising a circular tubular housing that can be impregnated with aromatic substance and emanate therefrom. An elastic band with an attached pocket is located within the chamber of the tubular housing. Alternatively, the tubular housing can be made of elasticized material. The pocket houses the atomizer spray bottle which can be filled with fragrance or scent. The pocket opening is covered with overlapping elasticized material attached to the tubular housing, which allows easy access to the atomizer spray bottle. The aroma device can be worn on the wrist; when the atomizer spray bottle is removed, it can be worn in the hair for scent. In another embodiment of the present invention, an ornamental three dimensional stuffed structure is located on a portion of the tubular housing. The atomizer spray bottle is housed within the stuffed structure.

A smart jewelry device to provide smart reminder and social functionalities is disclosed. This smart jewelry device having embedded SOC chip, illumination units, micro vibration motors can be controlled by mobile devices. This smart jewelry device can be configured to flicker or vibrate following a specific pattern as user defined to reminder user a specific event happened in user's smart terminal device. This smart jewelry device provides a new way of data expression, that is, by encoding the data in including but not limited to Morse code, etc., so that the smart jewelry flashes according to the encoded data, and then the user uses the camera to scan the flashing smart jewelry to decode the data to obtain data, a social network system is built based on this data exchange method that can send or receive some interactive information of friends through the cloud server.

Provided is a 360-degree rotatable accessory. The 360 degree rotatable accessory can be used for various purposes such as a decoration of a bag, or a finger ring, a necklace, a bracelet, and an earring, can be rotated a predetermined angle, that is, 360 degrees around a coupling portion, that is, a body, and can be transformed into various shapes because it can be rotated a desired angle and firmly maintained at the angle, thereby having high commercial value and quality.

Provided is a 360-degree rotatable accessory. The 360 degree rotatable accessory can be used for various purposes such as a decoration of a bag, or a finger ring, a necklace, a bracelet, and an earring, can be rotated a predetermined angle, that is, 360 degrees around a coupling portion, that is, a body, and can be transformed into various shapes because it can be rotated a desired angle and firmly maintained at the angle, thereby having high commercial value and quality.

A jewelry chain having a plurality of links including a plurality of connecting links and one or a plurality of decorative links. Each decorative link comprises an outline of an alphanumeric character and becomes part of the chain by connection from at least two connecting links. The connecting links can easily pass through open sections of the alphanumeric character outline to allow rotation and sliding movement in at least two different directions so that the alphanumeric character can provide different appearances when the jewelry chain is worn. The chain can form or be incorporated in necklaces, bracelets or earrings.