Disclosed is a peramivir dry powder inhaler, comprising a peramivir API or its acceptable salt or hydrate, wherein a single-dose preparation has a content of 5˜30 mg; the particle size distribution D10 of the dry powder is 1.3˜2.2 μm, D50 is 3˜6 μm, and D90 is 6˜13 μm. The peramivir dry powder inhaler prepared can effectively lower the titer of the influenza A virus in mouse lungs, has a notable anti-virus effect, can significantly prolong survival time and reduce mortality rate. The drug efficacy of the peramivir dry powder inhaler is superior to those of the peramivir sodium chloride injection and oseltamivir phosphate. The peramivir dry powder inhaler has a specific lung targeting effect, with notable improvement in drug effectiveness and safety.

A dry powder inhaler for delivering medicament from at least one medicament carrier having a plurality of spaced-apart medicament doses. The inhaler includes a housing having regions for accommodating unused and used portions of the medicament carrier, a mouthpiece component extending from the housing and through which a user is able to inhale, a dispensing mechanism arranged in the housing for moving a medicament dose of the medicament carrier to the dispensing position, and a mouthpiece cover being rotatably connected to the housing for sequential movement about a rotation axis from a first position in which the mouthpiece component is completely covered to a second position in which the mouthpiece component is completely covered, and from the second position to a third position in which the mouthpiece component is completely uncovered, the second position being between the first and third positions.

Methods and apparatuses (e.g., systems, devices, etc.) for delivering a nebulized drug agent in the nasal passages concurrent with the lungs.

A device is provided for the self-administration of cannabinoids. The device includes a container having an opening on a first end thereof, a cap which releasably engages said first end of said container, and an assembly, including first and second modules, which is removably placed inside of the container. The first module includes a first element equipped with first and second threading, a receptacle for said solid medium, said receptacle being equipped with at least one surface feature which slidingly engages said first threading, and a solid medium which is seated in said receptacle and which contains at least one cannabinoid. The second module is equipped with a filter and has a first threading disposed on a first terminal portion thereof. Various accessories may be releasably attached to the container or assembly. Methods of using the device are also described.

A vaporization device includes a first portion and a second portion. The first portion includes a first body defining a first interior volume, a first half of a split-pod, a second half of a split-pod, an opening, a first heating apparatus, and a second heating apparatus. The first half of the split-pod is configured to hold a nicotine-containing liquid. The second half of the split-pod is configured to hold a non-nicotine-containing liquid. The opening separates the first half from the second half of the split-pod. The first heating apparatus is dedicated to the first half. The second heating apparatus is dedicated to the second half. The second portion includes a second body defining a second interior volume and a computing system. The computing system is disposed within the second interior volume. The computing system is configured to vary an amount of current supplied to the first and second heating apparatuses.

A device mouthpiece is provided wherein the mouthpiece comprises a cylindrical tube and a filter element, wherein the filter element comprises a frame and a filter medium secured to the frame; the frame defines an annular channel which receives therein an end portion of the cylindrical tube; the end portion of the cylindrical tube forms a friction fit within the annular channel; and wherein the filter element is secured to the cylindrical tube via the friction fit.

An aerosol inhalation spacer for use with a metered-dose inhaler canister is disclosed. The spacer includes a transparent chamber housing having a body with an input end and an output end and defining an interior space. A mouthpiece is connected to the output end of the chamber housing. An inhaler adapter is connected to the input end of the chamber housing. A valve member is disposed between the mouthpiece and the output end of the chamber housing, the valve member includes a one-way inhalation valve and a one-way exhalation valve. A flow indicator is connected to the inhaler adapter and extends into the interior space of the chamber housing for indicating an inhalation flow rate to the user.

Disclosed herein is a multidrug pain management package to dispense two or more medicaments to treat pain comprising a primary n-polygon, and one or more concentric m-polygons, wherein each side of the n-polygon and m-polygons have at least n or m-medicament chambers capable of holding the two or more medicaments. Also disclosed herein is a multidrug pain management package comprising a disk, wherein the disk is divided into equally spaced regions, and wherein each region has chambers capable of holding medicaments. Also disclosed herein are single formulations to treat pain.

A device for dispensing a fluid product, having a body (1) and a dispensing head (2) with a dispensing orifice (3) and axially movable. The body receives a vessel (10) containing one or two doses of product. The device has an electronic module (100) with a wireless communication module (101), a geographical location module (102), and a power source (103). The device has a sensor system (201, 202) for detecting and automatically signalling an attempt to use the device, the sensor system having a first sensor (201) arranged on the dispensing head (2) and a second sensor (202) on the body, the sensor system detecting handling representative of an attempt to use the device when the first and second sensors (201, 202) are activated simultaneously, the wireless communication module designed to make an automatic emergency call when the sensor system detects handling representative of an attempt to use the device.

A system may include an external device and an inhaler. The external device may include a processor, a communication circuit, and memory. The inhaler may include a mouthpiece, medicament, a mechanical dose counter, and an electronics module comprising a processor and a communication circuit. The electronics module may record a dosing event when the inhaler is actuated, such as when the mouthpiece cover is opened, and send a signal indicating the dosing event to the external device. The external device may receive a mechanical dose reading of the mechanical dose counter, determine an electronic dose reading based on the signal indicating the dosing event, determine that a discrepancy between the mechanical dose reading and the electronic dose reading exceeds a threshold, and notify the user of the discrepancy, for example, by providing a notification to the user by way of a mobile application residing on the external device.