During a medical procedure, a transseptal fenestration is made at a septum of the heart and a shunt is implanted into the transseptal fenestration. During the same medical procedure, a transapical puncture is made into a left ventricle of the heart. A prosthetic valve is delivered via the transapical puncture and implanted at a mitral valve of the heart. Subsequently to delivering the prosthetic valve and making the transseptal fenestration, the transapical puncture is closed. Other embodiments are also described.

A method and system of bending medical device components for customization to a particular medical procedure and patient while generally maintaining the ideal performance of the component. A medical professional embeds the medical device component into a bending tool. The medical professional then aligns an intended curve region of the medical device component within a bending region of the bending tool and imparts a curve in the bending region. Finally, the medical professional withdraws the medical device component from the bending tool, and utilizes the bent medical device component in the medical procedure. The system may be a kit comprising various medical device components for a particular medical procedure and a suitable bending tool for those components.

Various cranial surgery OSS registration device embodiments of the present disclosure encompass a cranial surgery facial mask (128), a mask optical shape sensor (126b) having a mask registration shape extending internally within the cranial surgery facial mask (128) and/or externally traversing the cranial surgery facial mask (128), a cranial surgery tool (101), and a tool optical shape sensor (126d) having a tool registration shape extending internally within the cranial surgery tool (101) and/or externally traversing the cranial surgery tool (101). The mask registration shape of the mask optical shape sensor (126b) and the tool registration shape of the tool optical shape sensor (126d) interactively define a spatial registration of the cranial surgery facial mask (128) and the cranial surgery facial mask (128) and the cranial surgery tool (101) to a cranial image.

Systems and methods for treating biologic fluids are disclosed. Some disclosed embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject, heat CSF to a target temperature, cool CSF to a target temperature, apply light treatment to CSF, separate cells via their dielectric properties, apply spiral and/or centrifugal separation, introduce additives to target particles, and/or apply combinations thereof. The method may include the steps of withdrawing fluid comprising CSF, treating the fluid, and returning a portion of the treated fluid to the subject. During operation of the system, various parameters may be modified, such as flow rate.

A chest valve including: a housing including an inlet configured to connect to a chest tube, an outlet and a fluid passage from the inlet to the outlet; and a one-way valve within the housing and included in the flow passage, wherein the one-way valve includes: (i) a first tubular strip wherein having an internal air passage and a first layer defining the air passage, wherein the first layer has a first thickness and the internal air passage of the first tubular strip is included in fluid passage of the housing; and (ii) a second tubular strip wherein having a second layer with a second thickness with a second thickness greater than the first thickness, wherein an outer surface of the second tubular strip is adjacent and overlaps an outer surface of the first tubular strip.

An atrial shunt regulation device, a braid tool and a braid method thereof. The left disk (1) and the right disk (2) of the atrial shunt regulation device are connected via the intermediate portion (3) as a single piece, and the left disk (1), the intermediate portion (3) and the right disk (2) are braided by a single braid wire (10). The ends of the braid wires are secured by one nut in the single-braid method, which reduces the number and size of the nuts and easily forms a cortical layer. The braid tool for braiding an atrial shunt regulation device comprises a cylinder braid body mold (20), the cylindrical braid body mold (20) includes positioning pins (21) that are evenly connected to an outer wall of the braid body mold. The braid method of the atrial shunt regulation device comprises braiding, thermoforming, braiding a binding-off wire, securing ends of wires by a nut, and thermoforming again. The braid method is easy, the process is easy, and the device can be made manually in small batches to reduce costs.

The present technology relates to interatrial shunting systems and methods. In some embodiments, the present technology includes interatrial shunting systems that include a shunting element having a lumen extending therethrough that is configured to fluidly couple the left atrium and the right atrium when the shunting element is implanted in a patient. The system can also include an anchoring mechanism coupled to the shunting element and configured to secure the shunting element within the patients heart.

The present technology relates to interatrial shunting systems and methods. In some embodiments, the present technology includes interatrial shunting systems that include a shunting element having a lumen extending therethrough that is configured to fluidly couple the left atrium and the right atrium when the shunting element is implanted in a patient. The system can also include an anchoring mechanism coupled to the shunting element and configured to secure the shunting element within the patients heart.

Systems, methods, and computer-readable media for providing a decision support solution to medical professionals to optimize medical care through data monitoring and feedback treatment are provided herein. In another embodiment, a computer-implemented method for modeling patient outcomes resulting from treatment in a specific medical area includes receiving patient-specific data associated with a patient, determining a plurality of possible patient states under which the patient can be categorized, a current patient state under which the patient can be categorized and determining probabilities of the patient transitioning from any of the possible patient states to every other possible patient state.

A porous conduit may be suitable for use in treating a tissue site, and may include a central lumen and a porous wall positioned substantially concentric about the central lumen. The porous wall may have an open porous structure that may define a plurality of interconnected pores in fluid communication with one another. As part of a system, the porous conduit may be used with a manifold adapted to be positioned at a tissue site, a sealing drape adapted to cover the manifold to provide a sealed space relative to the tissue site, and a therapy device including a reduced-pressure source. The porous conduit may be disposed in the sealed space and in fluid communication between the sealed space and the reduced-pressure source.