Disclosed herein are stable complexes with controlled particle size, increased apparent solubility and increased dissolution rate comprising as active compound Celecoxib, its salts, or derivatives thereof, which is useful in the treatment of osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis, ankylosing spondylitis, acute pain especially in cancer related acute pain, primary dysmenorrhea. More specifically, the complexes possess instantaneous redispersibility, increased apparent solubility and permeability that provide faster onset of action for acute pain relief and lower GI related side effects. Further disclosed are methods of formulating and manufacturing the complexes described herein, pharmaceutical compositions, and uses and methods of treatment.

A mixing assembly includes a main flow conduit having an inlet end and an opposite outlet, a source of pressurized air at the inlet end, a container of stucco in fluid communication with the flow conduit, and a source of water in fluid communication with the flow conduit between the outlet and the container. The pressurized air draws stucco from the container into the flow conduit, and also draws water into the flow conduit to form an atomized slurry.

The present invention relates to a method for preparing an aqueous or hydro-alcoholic colloidal solution of metal chalcogenide amorphous nanoparticles notably of the Cu.sub.2ZnSnS.sub.4 (CZTS) type and to the obtained colloidal solution. The present invention also relates to a method for manufacturing a film of large-grain crystallized semi-conducting metal chalcogenide film notably of CZTS obtained from an aqueous or hydro-alcoholic colloidal solution according to the invention, said film being useful as an absorption layer deposited on a substrate applied in a solid photovoltaic device.

Apparatus is provided that includes a surgical tool for use with solid particles and a physiological liquid solution. The surgical tool includes (a) a shaft unit, which is shaped so as to define a delivery lumen, and a distal opening, which is disposed within 10 mm of a distal end of the shaft unit, in fluid communication with the delivery lumen; (b) a composition source, which is coupled in fluid communication with the delivery lumen, and which is configured to provide a solid-liquid composition of the solid particles and the physiological liquid solution; and (c) a pump, which is configured to pump the solid-liquid composition through the distal opening via the delivery lumen.

Systems and methods related to preparing foamed cement for laboratory analysis are provided. A prepared cement slurry is placed in a cement reservoir cell configured to pressurize the cement slurry contained within the cement reservoir cell to a capture pressure. After pressurization, the cement slurry and a compressed gas are introduced into a foam generator. Foamed cement generated in the foam generator is introduced from the tee into a foam capture cell where it can cure prior to analysis.

A method of forming microcapsules having improved physical properties and release control as well as the microcapsules formed by the process wherein the capsule wall is formed by the concurrent polymerization of monomers, oligomer and/or prepolymers on the inside of the capsule wall and different monomers, oligomers and/or prepolymers on the exterior of the capsule wall as it forms.

Apparatus and methods for mixing and dispersing a dispersed phase in a medium comprise a rotating surface for receiving the medium and an atomizing apparatus positioned at the rotating surface for depositing aerosolized constituents of the dispersed phase into the medium. The medium is made receptive and the dispersed phase is aerosolized. Constituents of the aerosolized dispersed phase are deposited into the receptive medium to form a compound or composite. The medium may be deposited onto a rotating disk, and the dispersed phase may be sprayed onto the disk. A thin film can be generated on the disk to transfer, distribute, and disperse the dispersed phase. Liquid ligaments formed at the edge of the rotating disk further transfer, distribute, and disperse the dispersed phase into the medium. Ligaments may be broken into aerosols or deformed by attenuation/drawing to further promote transfer, distribution, and dispersion. A bulk composite/compound may be collected.

The purpose of the present disclosure is, in a bubble generating device provided with a bubble generating unit for generating minute bubbles in water flowing through the inside of the cylindrical main body unit, to improve the bubble generating efficiency of the bubble generating unit. Provided is a bubble generating device provided with a cylindrical main body unit and a bubble generating unit disposed within the main body, wherein: the bubble generating unit is provided with slits extending radially centered on one point within the main body unit in a cross-sectional plane of the main body unit, and a column part protruding from the inner peripheral surface of main body unit and formed on the peripheral edge of the slits; and the amount of protrusion of the column part is gradually reduced toward the upstream side from the peripheral edges of the slits, and the column part has a recessed part formed on the downstream surface.

A method for the manufacture of foamed plaster utilizing a mixture of powdered casting plaster, powdered limestone and hemp fibre. The mixture is fed into a Venturi apparatus (40) under the influence of gravity. Compressed air may be supplied to the Venturi apparatus (40) through an inlet pipe (41) causing air and solid particles to be sucked into the Venturi apparatus (40). The elongated tube is provided with an inlet nozzle arranged to receive a mixture of water mixed with detergent agents. Further, the tube (50) is provided with an inlet nozzle (56) arranged to receive compressed air such that the elongated tube (50) delivers the mixture to a mixing and spray head (60) so as to feed the resulting mixture to a moulding means.

The disclosed invention is device for preparation of an emulsion and a method for producing an emulsion. The method comprises the steps of: (1) causing water and a water-insoluble substance that is to be emulsified to become freely miscible under conditions of temperature and pressure in the vicinity of the vapor-liquid critical point of water; and (2) cooling the product comprised of the water-insoluble substance and water solved each other in the presence of a surfactant to obtain a liquid comprised of the water-insoluble substance dispersed in water or a liquid comprised of water dispersed in the water-insoluble substance. The present invention provides a new device and a new method for producing emulsions with high efficiency without requiring a long period of processing or a great amount of energy.