This invention relates to a method of using MOF adsorbents to remove elemental impurities from feed streams comprising active pharmaceutical ingredients (API). The process involves contacting the feed stream comprising API and elemental impurities with the MOF at purification conditions to obtain a purified stream with provides an API which has a concentration of the elemental impurity below its permitted daily exposure. The process can be carried in a batch mode where the MOF and feed stream are admixed in a vessel for a given amount of time or continuously by flowing the feed stream through a column or adsorbent bed containing the MOF adsorbent.

This invention relates to a method of using MOF adsorbents to remove elemental impurities from feed streams comprising active pharmaceutical ingredients (API). The process involves contacting the feed stream comprising API and elemental impurities with the MOF at purification conditions to obtain a purified stream with provides an API which has a concentration of the elemental impurity below its permitted daily exposure. The process can be carried in a batch mode where the MOF and feed stream are admixed in a vessel for a given amount of time or continuously by flowing the feed stream through a column or adsorbent bed containing the MOF adsorbent.

The present invention relates to novel microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions, from the gastrointestinal tract at an elevated rate without causing undesirable side effects. The preferred formulations are designed avoid increase in pH of urine in patients and/or avoid potential entry of particles into the bloodstream of the patient. Also disclosed is a method for preparing high purity crystals of UZSi-9 exhibiting an enhanced level of potassium exchange capacity. These compositions are particularly useful in the therapeutic treatment of hyperkalemia.

The present invention relates to novel microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions, from the gastrointestinal tract at an elevated rate without causing undesirable side effects. The preferred formulations are designed avoid increase in pH of urine in patients and/or avoid potential entry of particles into the bloodstream of the patient. Also disclosed is a method for preparing high purity crystals of UZSi-9 exhibiting an enhanced level of potassium exchange capacity. These compositions are particularly useful in the therapeutic treatment of hyperkalemia.

A metal-organic framework (MOF) and uses thereof are provided herein, including an MOF comprising a repeat unit of the formula [Zn.sub.2(H.sub.2O)L.0.5H.sub.2O].sub.n, wherein L is a ligand of the formula:

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The MOFs provided herein may be used in the separation of two or more gaseous molecules from each other. In some embodiments, the gaseous molecules are carbon dioxide and acetylene.

A dehydration method is a dehydration method for selectively separating water from a mixture that contains water, using a zeolite membrane having an AFX structure, and the method includes a step of supplying the mixture to a supply side space of the zeolite membrane having an AFX structure, and a step of making a pressure difference between the supply side space and a permeation side space of the zeolite membrane having an AFX structure.

The invention relates to a system for neutralizing asbestos, said system comprising a mobile neutralization unit (200) comprising: an asbestos waste sorting module (225), an asbestos grinder (255) and a hot acid bath (250) for rendering asbestos inert.

Preferably, the asbestos waste sorting module comprises: a window with glove boxes; and a conveyor for transporting the asbestos waste in front of the window.

In embodiments, the system comprises a means for containing the atmosphere within the mobile neutralization unit and/or the hot acid bath (250) of the mobile neutralization unit (200) comprises sulfuric acid.

A method for making metal organic frameworks (MOFs) includes the step of dissolving metal salts in deionized water to form first solution, followed by adding a cyclic propyl phosphonic anhydride reagent to the first solution to form a second solution. The second solution is heated to form a reaction mixture containing MOF crystals, and is then cooled. The MOF crystals are filtered therefrom, washed and dried. To make metal organic framework-based thin film nanocomposite membranes, the MOF crystals are mixed with an m-phenylene diamine aqueous solution to form a mixture, which is then poured on a top surface of an ultrafiltration membrane substrate to form a first intermediate membrane structure. The first intermediate membrane structure is dried, and trimesolyl chloride in n-hexane solution is poured thereon to form a second intermediate membrane structure, which is cured to form an MOF-based thin film nanocomposite membrane, which is then rinsed and dried.

This disclosure relates to new crystalline microporous solids (including silicate- and aluminosilicate-based solids), the compositions comprising 8 and 10 membered inorganic rings, particularly those having IWV topologies having a range of Si:Al ratios, methods of preparing these and known crystalline microporous solids using certain quaternized imidazolium cation templates.

This disclosure relates to new crystalline microporous solids (including silicate- and aluminosilicate-based solids), the compositions comprising 8 and 10 membered inorganic rings, particularly those having IWV topologies having a range of Si:Al ratios, methods of preparing these and known crystalline microporous solids using certain quaternized imidazolium cation templates.