Provided herein is a process for preparing triaryl organoborates of the formula 1/n K.sup.n+R.sub.3.sup.4B.sup.−—R.sup.1 (IV), where one equivalent of organoboronic ester of the formula B—R.sup.1(OR.sup.2)(OR.sup.3) (I) is initially charged together with 1/n equivalents of salt K.sup.n+ nX.sup.− (II) and 3 equivalents of metal M in a solvent or a solvent mixture S1, 3 equivalents of a haloaromatic R.sup.4—Y (III) are added, an auxiliary L and optionally a second organic solvent or solvent mixture S2 is added and the compound 1/n K.sup.n+ R.sub.3.sup.4B.sup.−—R.sup.1 (IV) is separated off with the organic phase, and to the use of these substances as co-initiator in photopolymer formulations.

The present invention provides compounds of the formula (I) and their use as Kv3 modulators. ##STR00001##

The present invention provides compounds of the formula (I) and their use as Kv3 modulators. ##STR00001##

Pharmaceutical compositions of the invention comprise functionalized N,N-dialkylamino phenyl ethers derivatives having a disease-modifying action in the treatment of diseases associated with lysosomal storage dysfunction that include Gaucher's disease, and any disease or condition involving lysosomal storage dysfunction.

The present invention provides compounds of the formula (I) and their use as Kv3 modulators.

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A lubricating oil friction modifier and a preparation method therefor and use thereof are provided. The lubricating oil friction modifier has a chemical formula of A.sub.xB.sup.y+(C.sup.?).sub.y. In the formula, A is a perfluoropolyether acyl group, B.sup.y+ represents a cationic group having x amino groups and y ammonium ions, C.sup.? is BF.sub.4.sup.?, PF.sub.6.sup.?, AsF.sub.6.sup.?, FAP.sup.?, TFSI.sup.?, Mn.sub.2O.sub.4 or ClO.sub.4.sup.?, x is an integer greater than or equal to 1, y is an integer greater than or equal to 1, and x+y?2. The lubricating oil friction modifier has a good solubility with fluorine oil and fluorine grease, will not precipitate in the fluorine oil and the fluorine grease after being added, and can significantly improve the wear resistance of a lubricating oil such as the fluorine oil and the fluorine grease.

New cationic lipids are provided that are useful for delivering macromolecules, such as nucleic acids, into eukaryotic cells. The lipids can be used alone, in combination with other lipids and/or in combination with other transfection enhancing reagents to prepare transfection complexes.

Disclosed herein, inter alia, are compositions and methods useful for treating non-alcoholic fatty liver diseases.

A lubricating oil friction modifier and a preparation method therefor and use thereof are provided. The lubricating oil friction modifier has a chemical formula of A.sub.xB.sup.y+(C.sup.).sub.y. In the formula, A is a perfluoropolyether acyl group, B.sup.y+ represents a cationic group having x amino groups and y ammonium ions, C.sup. is BF.sub.4.sup., PF.sub.6.sup., AsF.sub.6.sup., FAP.sup., TFSI.sup., Mn.sub.2O.sub.4 or ClO.sub.4.sup., x is an integer greater than or equal to 1, y is an integer greater than or equal to 1, and x+y2. The lubricating oil friction modifier has a good solubility with fluorine oil and fluorine grease, will not precipitate in the fluorine oil and the fluorine grease after being added, and can significantly improve the wear resistance of a lubricating oil such as the fluorine oil and the fluorine grease.

Compound of Formula (1); wherein: Z.sup.w is an organic radical comprising w amino groups, in which w is a number and 5w3,000; A and B are independently oxy-C.sub.1-C.sub.20-alkylene carbonyl groups or oxy-C.sub.2-C.sub.20-alkenylene carbonyl groups derived from hydroxy carboxylic acids or lactones; T is hydrogen or RCO, where R is a C.sub.1-C.sub.50 hydrocarbyl group; Y is a C.sub.3-C.sub.4-alkylene radical linked to an amino group of Z.sup.w; Y is an ionic salt link between an amino group of Z.sup.w and the terminal carbonyl of (A).sub.r-(B).sub.p-T; r and p are independently numbers between 0 and 50 and r+p>2; s, m and v are numbers; 0.99ws+m2w; and 0.3ws+v2w are suitable as dispersants and milling aids. ##STR00001##