Disclosed are compounds of Formula (I) ##STR00001##
or a salt thereof, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

Disclosed are compounds of Formula (I) ##STR00001##
or a salt thereof, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

A process for removing impurities from a liquid azole heteroaromatic compound-containing (e.g., triazole-containing) mixture by: (a) providing a liquid azole heteroaromatic compound-containing mixture having impurities; and (b) passing the azole heteroaromatic compound-containing mixture through at least one filtration membrane which is a nanofiltration membrane and/or ultrafiltration membrane having a molecular pore size in the range of from about 200 daltons to about 1 kilodaltons to provide a permeate that is an at least partially purified azole heteroaromatic compound-containing mixture and a retentate with at least some impurities.

Disclosed are tris(triazolylmethyl)amine ligands, and kits and methods for labeling and/or imaging a biomolecule of interest in a subject or living system.

Disclosed are compounds of Formula (I)

##STR00001##

or a salt thereof, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

Disclosed are compounds of Formula (I)

##STR00001##

or a salt thereof, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

Disclosed are compounds of Formula (I)

##STR00001##

or a salt thereof, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

Disclosed are compounds of Formula (I)

##STR00001##

or a salt thereof, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

Disclosed are compounds of Formula (I) ##STR00001##
or a salt thereof, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.

Disclosed are compounds of Formula (I) ##STR00001##
or a salt thereof, wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, m, n, and p are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.