C07D325/00

COVALENT INHIBITORS OF CDK-7
20180008604 · 2018-01-11 ·

The disclosure includes compounds of Formula (I)

##STR00001## wherein R.sub.0, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and L are defined herein. Also disclosed is a method for treating a neoplastic disease, autoimmune disease, and inflammatory disorder with these compounds.

COVALENT INHIBITORS OF CDK-7
20180008604 · 2018-01-11 ·

The disclosure includes compounds of Formula (I)

##STR00001## wherein R.sub.0, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and L are defined herein. Also disclosed is a method for treating a neoplastic disease, autoimmune disease, and inflammatory disorder with these compounds.

AGROCHEMICAL ADJUVANT CONTAINING 2-OXO-1,3-DIOXOLAN-4 CARBOXYLATES

The present invention relates to a method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant which comprises a carbonate of the formula (I); to a pesticide formulation comprising the tank mix adjuvant; to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix or the pesticide formulation is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment; and to a use of the tank mix adjuvant for increasing the efficacyl of a pesticide.

AGROCHEMICAL ADJUVANT CONTAINING 2-OXO-1,3-DIOXOLAN-4 CARBOXYLATES

The present invention relates to a method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant which comprises a carbonate of the formula (I); to a pesticide formulation comprising the tank mix adjuvant; to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix or the pesticide formulation is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment; and to a use of the tank mix adjuvant for increasing the efficacyl of a pesticide.

TRAINING AID FOR TRAINING IN THE DETECTION OF TRIACETONE TRIPEROXIDE (TATP), PRODUCTION METHODS AND USE FOR DOG TRAINING

Baits for training in the detection of explosives including triacetone triperoxide (TATP) adsorbed in the form of a solid or gas on a solid support include a cellulosic material, in particular cellulose acetate. Production processes for producing the baits for training in the detection of explosives are also related from acetone, hydrogen peroxide and an acid in a molar ratio, as well as the use of these baits in training dogs for the detection of TATP explosives, are also described.

TRAINING AID FOR TRAINING IN THE DETECTION OF TRIACETONE TRIPEROXIDE (TATP), PRODUCTION METHODS AND USE FOR DOG TRAINING

Baits for training in the detection of explosives including triacetone triperoxide (TATP) adsorbed in the form of a solid or gas on a solid support include a cellulosic material, in particular cellulose acetate. Production processes for producing the baits for training in the detection of explosives are also related from acetone, hydrogen peroxide and an acid in a molar ratio, as well as the use of these baits in training dogs for the detection of TATP explosives, are also described.

SYNTHESIZING DRUG-ORGANIC-ACID-ANHYDRIDE CONJUGATES WITHOUT USING COUPLING REAGENT
20210315998 · 2021-10-14 ·

Synthesizing a drug-organic-acid-anhydride conjugate using docetaxel as a drug, including: mixing aconitic anhydride with a chlorinating reagent to produce a first mixture; dissolving the first mixture in an organic solvent to produce a dissolved mixture; stirring the dissolved mixture; evaporating the organic solvent from the dissolved mixture to produce a second mixture; washing the second mixture with an impurity remover to remove impurities and to produce an aconitic anhydride chloride solution; and mixing the docetaxel with the aconitic anhydride chloride solution to produce the drug-organic-acid-anhydride conjugate.

METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES

The present invention relates to a method for the synthesis of cyclic depsipeptides, in particular emodepside, from the open form.

METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES

The present invention relates to a method for the synthesis of cyclic depsipeptides, in particular emodepside, from the open form.

COVALENT INHIBITORS OF CDK-7
20200297724 · 2020-09-24 ·

The disclosure includes compounds of Formula (I)

##STR00001## wherein R.sub.0, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, and L are defined herein. Also disclosed is a method for treating a neoplastic disease, autoimmune disease, and inflammatory disorder with these compounds.