A compact radio-frequency quadrupole ‘RFQ’ accelerator for accelerating charged particles, the RFQ accelerator comprising: a bunching section configured to have a narrow radio-frequency ‘rf’ acceptance such that only a portion of a particle beam incident on the bunching section is captured, and wherein the bunching section bunches the portion of the particle beam; an accelerating section for accelerating the bunched portion of the particle beam to an output energy; and, a means for supplying radio-frequency power.

A device such as a medical device and a method for making same provides a device surfaces modified by beam irradiation, such as a gas cluster ion beams or a neutral beam, to inhibit or delay attachment or activation or clotting of platelets or to match surface energy of the device to that of a protein with the property of inhibition of bacterial colonization that can coat the all or part of the device surface to effect such inhibition.

Some embodiments include a system comprising: an RF source configured to generate an RF signal; an RF frequency control circuit coupled to the RF source and configured to adjust a frequency of the RF signal; an accelerator structure configured to accelerate a particle beam in response to the RF signal; and control logic configured to: receive a plurality of settings over time for the RF source; adjust the RF signal in response to the settings; and adjust a setpoint of the RF frequency control circuit in response to the settings.

A proton beam imaging system includes: a proton beam generator to generate a proton beam; a proton beam modulator through which the proton beam passes positioned between the proton beam generator and an image target; and a proton beam detector positioned to detect the proton beam existing the image target; wherein the proton beam modulator comprises: a rotating wheel having an axis of rotation positioned so that the proton beam passes through the axis of rotation and the axis of rotation is perpendicular to the proton beam; a first modulating portion comprising a first material portion and a second material portion through which a proton beam passes; and a second modulating portion comprising a third material portion and a fourth material portion through with the proton beam passes; wherein the first and second wedges are positioned opposite each other on the rotating wheel.

An device is for electron-beam irradiation sterilization of flexible bags that may contain human plasma protein solutions for therapeutic use. The device has two electron accelerators, a first accelerator emitting an electron beam with energies between 400 and 500 keV and a second accelerator emitting an electron beam with an energy of at least 4 MeV. A sterilization method by electron-beam irradiation provides sterilization of such flexible bags. An in-line filling process for flexible bags can use the sterilization device and method.

Some embodiments include a system comprising: a particle power source configured to generate a particle power signal; a radio frequency (RF) power source configured to generate an RF power signal; a particle source configured to generate a particle beam in response to the particle power signal; a RF source configured to generate an RF signal in response to the RF power signal; and an accelerator structure configured to accelerate the particle beam in response to the RF signal; wherein a timing of the RF power signal is different from a timing of the particle power signal.

A proton beam imaging system includes: a proton beam generator to generate a proton beam; a proton beam modulator through which the proton beam passes positioned between the proton beam generator and an image target; and a proton beam detector positioned to detect the proton beam existing the image target; wherein the proton beam modulator comprises: a rotating wheel having an axis of rotation positioned so that the proton beam passes through the axis of rotation and the axis of rotation is perpendicular to the proton beam; a first modulating portion comprising a first material portion and a second material portion through which a proton beam passes; and a second modulating portion comprising a third material portion and a fourth material portion through with the proton beam passes; wherein the first and second wedges are positioned opposite each other on the rotating wheel.

Some embodiments include a system comprising: an RF source configured to generate an RF signal; an RF frequency control circuit coupled to the RF source and configured to adjust a frequency of the RF signal; an accelerator structure configured to accelerate a particle beam in response to the RF signal; and control logic configured to: receive a plurality of settings over time for the RF source; adjust the RF signal in response to the settings; and adjust a setpoint of the RF frequency control circuit in response to the settings.

Some embodiments include a system comprising: a particle power source configured to generate a particle power signal; a radio frequency (RF) power source configured to generate an RF power signal; a particle source configured to generate a particle beam in response to the particle power signal; a RF source configured to generate an RF signal in response to the RF power signal; and an accelerator structure configured to accelerate the particle beam in response to the RF signal; wherein a timing of the RF power signal is different from a timing of the particle power signal.

Some embodiments include a system comprising: a first control logic configured to receive a first trigger and generate a second trigger in response to the first trigger the second trigger having a delay relative to the first trigger of a configurable number of cycles of a counter of the first control logic; a second control logic configured to receive the second trigger and generate a third trigger in response to the second trigger the third trigger having a delay relative to the second trigger of a configurable number of cycles of a counter of the second control logic; and a third control logic configured to receive the second trigger and generate a fourth trigger in response to the second trigger the fourth trigger having a delay relative to the second trigger of a configurable number of cycles of a counter of the third control logic. A particle beam may be accelerated in response to the triggers.