Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.

Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.

A converter for generating photons from an electron beam is provided. The converter may include a plurality of converter plates (i) positioned perpendicular to an axis and (ii) arranged sequentially in a direction along the axis from a first converter plate of the plurality of converter plates to a last converter plate of the plurality of converter plates. The first converter plate may be configured to receive an electron beam traveling in the direction along the axis. Further, the first converter plate may have a thickness smaller than a thickness of the last converter plate, wherein a thickness of a particular converter plate is measured along the axis.

Passivation regions and device configurations are described herein. The passivation regions can be configured to seal against diffusion of an objective material from an underlying region into and/or through the passivation region. The passivation regions can also be configured to seal against diffusion of an externally sourced or ambient substance into and/or through the passivation region towards the underlying region.

Passivation regions and device configurations are described herein. The passivation regions can be configured to seal against diffusion of an objective material from an underlying region into and/or through the passivation region. The passivation regions can also be configured to seal against diffusion of an externally sourced or ambient substance into and/or through the passivation region towards the underlying region.

Design and making methods of a neutrons generating target are described. In some embodiments, a surface of a target substrate can be modified to form one or more surface features. In some embodiments, a neutron source layer can be disposed on the surface of the target substrate. In some embodiments, the neutron source layer and the target substrate can be heated to an elevated temperature to form a bond between the two. In some embodiments, the surface modification of the target substrate can reduce blistering and material exfoliation in the target. The target can be used in boron neutron capture therapy.

Design and making methods of a neutrons generating target are described. In some embodiments, a surface of a target substrate can be modified to form one or more surface features. In some embodiments, a neutron source layer can be disposed on the surface of the target substrate. In some embodiments, the neutron source layer and the target substrate can be heated to an elevated temperature to form a bond between the two. In some embodiments, the surface modification of the target substrate can reduce blistering and material exfoliation in the target. The target can be used in boron neutron capture therapy.

An irradiation target system having an irradiation target with at least one annular plate defining a central opening and including an elongated body, a flange portion, and a tab portion, wherein the flange portion extends beyond a first end of the plurality of plates, a target debundling tool, having a base plate, a gripper assembly affixed to the base plate, and a twister assembly including a housing defining a target bore configured to receive the target therein, and a slide portion that is slidably and non-rotatably mounted to the housing at a bottom end of the target bore.

A heat dissipation structure includes a housing. The housing has a bottom surface, a liquid inlet channel, a liquid outlet channel and a protruding portion. The liquid inlet channel and the liquid outlet channel are located at two opposite ends of the housing and above the bottom surface. The liquid inlet channel and the liquid outlet channel extend along a first direction. The protruding portion is located between the liquid inlet channel and the liquid outlet channel and above the bottom surface. The protruding portion protrudes towards a direction away from the bottom surface. The protruding portion has a protruding surface facing away from the bottom surface. A distance between the protruding surface and the bottom surface is increased first and then decreased along the first direction.

A target carrier assembly includes a housing, a target, and a collimator. The housing includes a collimator compartment and a target compartment divided by a vacuum window foil, the collimator being removably disposed within the collimator compartment, and the target being disposed within the target compartment. The collimator compartment is attached to a cyclotron beam line in the irradiation position, and the target compartment is in fluid communication with a cooling fluid supply line and a cooling fluid return line in the irradiation position. The target is cooled by the cooling fluid from the cooling fluid supply line. The collimator directs a particle beam from the cyclotron beam line to irradiate the target and includes a beam entry diameter and a beam exit diameter. The collimator is in thermal contact with the collimator compartment.