This disclosure describes enzymes from the type II (a discrete set of enzymes) fatty acid synthesis (FAS) pathway that can be used in combination with thiolases to operate a functional reversal of the -oxidation cycle. A combination of thiolases with one or more of 3-oxoacyl-[acyl-carrier-protein] reductase (FabG, others), 3-hydroxyacyl-[acp] dehydratase (FabA, FabZ, others), and enoyl-[acyl-carrier-protein] reductase (FabI, FabK, FabL, FabV, others) yields a functional reversal of the -oxidation cycle. If only one or two enzymes are used, the remaining enzymes will be traditional beta oxidation enzymes. Once this cycle is coupled with the appropriate priming and termination pathways, the production of carboxylic acids, alcohols, hydrocarbons, amines and their -, -, and -functionalized derivatives from renewable carbon sources can be achieved.

Methods and materials for the production of compounds involved in fatty acid metabolism, and/or derivatives thereof and/or compounds related thereto are provided. Also provided are products produced in accordance with the methods and materials of the present invention.

Provided are genetically engineered microorganism that catalyze the synthesis of propane and/or butanol from a suitable substrate such as glucose. Also provided are methods of engineering said genetically engineered microorganism and methods of producing propane and/or butanol using the genetically engineered microorganism.

Provided are genes, coding proteins and uses thereof, gene elements, genes and uses, gene elements, methods for synthesizing odd numbered medium chain aliphatic aldehydes, for synthesizing odd numbered medium chain aliphatic alcohol and for synthesizing even numbered medium chain aliphatic hydrocarbons. Provided is method for producing odd numbered aliphatic alcohols in Escherichia coli. An -dioxygenase from rice is used without additional deoxidization and energy supply from cells. The -dioxygenase can also be used for synthesizing aliphatic alcohols with different proportions of C11 to C15 by co-working with different thioesterases.

Compositions and methods for producing aldehydes, alkanes, and alkenes are described herein. The aldehydes, alkanes, and alkenes can be used in biofuels.

Provided are genes, coding proteins and uses thereof, gene elements, genes and uses, gene elements, methods for synthesizing odd numbered medium chain aliphatic aldehydes, for synthesizing odd numbered medium chain aliphatic alcohol and for synthesizing even numbered medium chain aliphatic hydrocarbons. Provided is method for producing odd numbered aliphatic alcohols in Escherichia coli. An -dioxygenase from rice is used without additional deoxidization and energy supply from cells. The -dioxygenase can also be used for synthesizing aliphatic alcohols with different proportions of C11 to C15 by co-working with different thioesterases.

Compositions and methods for producing hydrocarbons such as aldehydes, alkanes, and alkenes are described herein. Certain hydrocarbons can be used in biofuels.

Compositions and methods for producing aldehydes, alkanes, and alkenes are described herein. The aldehydes, alkanes, and alkenes can be used in biofuels.

Compositions and methods for producing hydrocarbons such as aldehydes, alkanes, and alkenes are described herein. Certain hydrocarbons can be used in biofuels.