Squalene Hopene Cyclase (SHC) enzymes and variants thereof and their uses for making ()-Ambrox from homofarnesol and Ambra oxide from bishomofarnesol and the like.

A method for purifying a crude flavor or perfumery or cosmetic ingredient or intermediate, for example crude ()-Ambrox, comprising a number of washing steps, the products of said method, and uses of said product.

An enzyme-mediated method for the production of Amberketal and Amberketal homologues, the products of said method, and uses of said products.