A sterilization particle includes a porous carrier material having at least one of the following: a microporous material, a mesoporous material, a macroporous material, or a combination thereof; and a sterilization material contained in pores of the porous carrier material or adsorbed on a surface of the porous carrier material. The sterilization material includes at least 4 weight percent of the sterilization particle. A sterilization device, a method for preparing a sterilization particle, and a method for sterilizing a space are also disclosed.

Aspects of the disclosure relate to wet transcatheter prosthetic heart valve or other implant packaging and assemblies in which a prosthetic heart valve or other implant is loaded into a first portion of a delivery device and positioned within a container in which sterilizing fluid is retained to sterilize interior portions of the container as well as provide moisture to prevent the implant from drying out. The disclosure also relates to methods of sterilizing the disclosed assemblies. Some disclosed methods include at least two sterilizing steps and adjustment of a mechanical seal member or formation of multiple seals so that areas proximate the seals are also sterilized during the sterilization process.