The present invention discloses a cobalt compound of formula (I), a process for the preparation and use thereof. The present invention further relates to a pharmaceutical composition and a method inhibition of Tau Aggregation in a subject in need thereof using compound of formula (I).

##STR00001##

The present invention discloses a cobalt compound of formula (I), a process for the preparation and use thereof. The present invention further relates to a pharmaceutical composition and a method inhibition of Tau Aggregation in a subject in need thereof using compound of formula (I).

##STR00001##

A compound having an excellent rate of change in HTP caused by exposure is achieved and is represented by General Formula (1). In addition, a composition is formed of the compound, and a cured product, an optically anisotropic body, or a reflective film is obtained by curing the composition. ##STR00001##

A compound having an excellent rate of change in HTP caused by exposure is achieved and is represented by General Formula (1). In addition, a composition is formed of the compound, and a cured product, an optically anisotropic body, or a reflective film is obtained by curing the composition. ##STR00001##

An apparatus (10) for the preparation of acetylene and synthesis gas by partial oxidation of hydrocarbons with oxygen is proposed. The apparatus (10) comprises a reactor (12), wherein the reactor (12) comprises a burner block (14) with a furnace chamber for the preparation of a composition C1 comprising at least acetylene and substituted acetylene, a first scrubber (22) which is constructed for adding a solvent to the composition C1 to obtain a composition C2, a second scrubber (26) which is constructed for adding the solvent to the composition C2 to obtain a composition C3, a first stripper (36) which is constructed for stripping the composition C3 to obtain a composition C4 comprising the substituted acetylene, acetylene and the solvent and for separating off the acetylene, a first column (46) which is constructed for partial degassing of the composition C4 under a pressure of from 1.0 bar to 1.5 bar to obtain a composition C5 and a first amount A1 of the solvent, a second stripper (56) to which the composition C5 can be fed for stripping a composition C9 to obtain a second amount A2 of the solvent and a composition C6, a third stripper (68) which is constructed for stripping the solvent from the first scrubber (22) to obtain a composition C9, wherein the third striper (68) is connected to the second stripper (56) for feeding the composition C9 to the second stripper (56), an apparatus (72) for adding a diluting gas to the composition C5, which is arranged between the first column (46) and the second stripper (56), a second column (76) which is constructed for adding water to the composition C6 to obtain a composition C7 comprising a third amount A3 of the solvent and water and to obtain a composition C8 comprising the substituted acetylene, and a mixing condenser (82) which is constructed for adding water to the composition C8 to obtain a composition C11 comprising the substituted acetylene. A process for the preparation of acetylene and synthesis gas by partial oxidation of hydrocarbons with oxygen is further proposed.

An apparatus (10) for the preparation of acetylene and synthesis gas by partial oxidation of hydrocarbons with oxygen is proposed. The apparatus (10) comprises a reactor (12), wherein the reactor (12) comprises a burner block (14) with a furnace chamber for the preparation of a composition C1 comprising at least acetylene and substituted acetylene, a first scrubber (22) which is constructed for adding a solvent to the composition C1 to obtain a composition C2, a second scrubber (26) which is constructed for adding the solvent to the composition C2 to obtain a composition C3, a first stripper (36) which is constructed for stripping the composition C3 to obtain a composition C4 comprising the substituted acetylene, acetylene and the solvent and for separating off the acetylene, a first column (46) which is constructed for partial degassing of the composition C4 under a pressure of from 1.0 bar to 1.5 bar to obtain a composition C5 and a first amount A1 of the solvent, a second stripper (56) to which the composition C5 can be fed for stripping a composition C9 to obtain a second amount A2 of the solvent and a composition C6, a third stripper (68) which is constructed for stripping the solvent from the first scrubber (22) to obtain a composition C9, wherein the third striper (68) is connected to the second stripper (56) for feeding the composition C9 to the second stripper (56), an apparatus (72) for adding a diluting gas to the composition C5, which is arranged between the first column (46) and the second stripper (56), a second column (76) which is constructed for adding water to the composition C6 to obtain a composition C7 comprising a third amount A3 of the solvent and water and to obtain a composition C8 comprising the substituted acetylene, and a mixing condenser (82) which is constructed for adding water to the composition C8 to obtain a composition C11 comprising the substituted acetylene.

A process for the preparation of acetylene and synthesis gas by partial oxidation of hydrocarbons with oxygen is further proposed.

Embodiments of the present disclosure provide for Rh(I) catalysts, methods of making alkenyl substituted arenes (e.g., allyl arene, vinyl arene, and the like), methods of making alkyl substituted arenes, and the like.

Embodiments of the present disclosure provide for Rh(I) catalysts, methods of making alkenyl substituted arenes (e.g., allyl arene, vinyl arene, and the like), methods of making alkyl substituted arenes, and the like.

A process of preparing olefins of the formula (I) is described herein: ##STR00001##
with R.sup.1 being a substituted or unsubstituted (C.sub.1-C.sub.30)hydrocarbyl, and R.sup.2 being a substituted or unsubstituted (C.sub.1-C.sub.20)hydrocarbyl. The process includes reacting a compound of formula (II) ##STR00002##
wherein Ar is chosen from ##STR00003##
in the presence of a palladium-based catalyst and an organic solvent. A process of preparing olefins of the formula (III) is also described: ##STR00004##
with R.sup.3 being a substituted or unsubstituted (C.sub.1-C.sub.30)hydrocarbyl, R.sup.4 being a substituted or unsubstituted (C.sub.1-C.sub.20)hydrocarbyl, and R.sup.5 being a substituted or unsubstituted (C.sub.1-C.sub.30) hydrocarbyl. The process includes reacting a compound of formula (IV) ##STR00005##
wherein Ar is chosen from ##STR00006##
with a compound of formula (V) ##STR00007##
wherein Ar is chosen from ##STR00008##
in the presence of a palladium-based catalyst and an organic solvent.

A process of preparing olefins of the formula (I) is described herein: ##STR00001##
with R.sup.1 being a substituted or unsubstituted (C.sub.1-C.sub.30)hydrocarbyl, and R.sup.2 being a substituted or unsubstituted (C.sub.1-C.sub.20)hydrocarbyl. The process includes reacting a compound of formula (II) ##STR00002##
wherein Ar is chosen from ##STR00003##
in the presence of a palladium-based catalyst and an organic solvent. A process of preparing olefins of the formula (III) is also described: ##STR00004##
with R.sup.3 being a substituted or unsubstituted (C.sub.1-C.sub.30)hydrocarbyl, R.sup.4 being a substituted or unsubstituted (C.sub.1-C.sub.20)hydrocarbyl, and R.sup.5 being a substituted or unsubstituted (C.sub.1-C.sub.30) hydrocarbyl. The process includes reacting a compound of formula (IV) ##STR00005##
wherein Ar is chosen from ##STR00006##
with a compound of formula (V) ##STR00007##
wherein Ar is chosen from ##STR00008##
in the presence of a palladium-based catalyst and an organic solvent.