The present invention relates to esters of at least one sugar polyol and of at least one C.sub.6-C.sub.11 linear fatty acid wherein the sugar polyol is erythritol.

The present invention relates to esters of at least one sugar polyol and of at least one C.sub.6-C.sub.11 linear fatty acid wherein the sugar polyol is erythritol.

Methods and compositions containing a phorbol ester or derivative of a phorbol ester are provided for prevention and treatment of sudden acute respiratory syndrome (SARS) coronavirus infection, including SARS-CoV-2 infection and related COVID-19 disease. Also provided are methods and compositions for preventing and treating acute inflammatory conditions and related pathogenic injuries, including Acute Respiratory Distress Syndrome (ARDS) and cytokine storm syndrome (CSS) seen in severe SARS-CoV-2/COVID-19 cases.

The present disclosure relates to methods and compositions for making bio-based, biodegradable, and non-bioaccumulating lubricating base oils generated by esterifying alkoxylated polyols (average alkoxylation ≥3) with long-chain (≥C14) saturated and unsaturated fatty acids (FA) or fatty acids modified using industry recognized techniques.

It is provided an ester for a refrigerator oil and of mixed alcohols and mixed monocarboxylic acids. The mixed alcohols include dipentaerythritol and tripentaerythritol in a mass ratio of 90/10 to 99.7/0.3, and the mixed monocarboxylic acids include n-pentanoic acid and 2-methyl butanoic acid in a mass ratio of 50/50 to 80/20. The ester has a kinematic viscosity of 50 to 150 mm.sup.2/s at 40° C.

It is provided an ester for a refrigerator oil and of mixed alcohols and mixed monocarboxylic acids. The mixed alcohols include dipentaerythritol and tripentaerythritol in a mass ratio of 90/10 to 99.7/0.3, and the mixed monocarboxylic acids include n-pentanoic acid and 2-methyl butanoic acid in a mass ratio of 50/50 to 80/20. The ester has a kinematic viscosity of 50 to 150 mm.sup.2/s at 40° C.

Described herein are methods of stabilizing the beta hydrogen of glycerol based esters by the insertion of alkoxy groups to significantly improve the thermal, oxidative, and hydrolytic stability of the ester and allow for controlling the molar density of esters bonds in the lubricants to maximize hydrolytic stability while maintaining biodegradability and further improving performance properties.

This oily moisturizer is composed of either an esterified product of a component A that is ditrimethylolpropane, and a component B that is one fatty acid, or two or more fatty acids, selected from among saturated fatty acids of 6 to 12 carbon atoms, or an esterified product of the component A, the component B, and a component C that is one fatty acid, or two or more fatty acids, selected from among fatty acids of 13 to 28 carbon atoms, wherein the hydroxyl value of the esterified product is not more than 140 mgKOH/g, and the mass ratio between fatty acid residues derived from the component B and fatty acid residues derived from the component C within the fatty acid residues that constitute the esterified product of the component A, the component B and the component C is within a range from 99.9:0.1 to 60:40.

The present invention relates to a derivative of 13-oxidized ingenol, use thereof in the prevention and/or treatment of a disease associated with proliferation or tumor in a subject, or a cosmetic indication, and use thereof in the prevention and/or treatment of a disease responsive to neutrophil oxidative burst, a disease responsive to a release of IL-8 by keratinocyte, or a disease responsive to induction of necrosis.

The present invention relates to a derivative of 13-oxidized ingenol, use thereof in the prevention and/or treatment of a disease associated with proliferation or tumor in a subject, or a cosmetic indication, and use thereof in the prevention and/or treatment of a disease responsive to neutrophil oxidative burst, a disease responsive to a release of IL-8 by keratinocyte, or a disease responsive to induction of necrosis.