The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.

A process for preparing b-b dimers having anti-UV and antioxidant properties, from p-hydroxycinnamic esters and amides disubstituted in the ortho position with respect to the phenol function and from ketones disubstituted in the ortho position with respect to the phenol, in particular, from sinapic acid esters and amides and ketone analogs. The dimers of formulae (I), (II), (III) and (IV) as obtained by means of the process according to the present disclosure can be used for the production of polymers/plastics (in plastics technology), or for the protection of plants against the cold and as cosmetic or food-processing ingredients, for example. The process may be used to form biobased anti-UV molecules.

A process for preparing b-b dimers having anti-UV and antioxidant properties, from p-hydroxycinnamic esters and amides disubstituted in the ortho position with respect to the phenol function and from ketones disubstituted in the ortho position with respect to the phenol, in particular, from sinapic acid esters and amides and ketone analogs. The dimers of formulae (I), (II), (III) and (IV) as obtained by means of the process according to the present disclosure can be used for the production of polymers/plastics (in plastics technology), or for the protection of plants against the cold and as cosmetic or food-processing ingredients, for example. The process may be used to form biobased anti-UV molecules.

A composition comprised of a component selected from the group consisting of a biobased bis-alkyl succinate and a biobased bis-alkyl sebacate, each derived, for example, from the esterification of biobased diacid such as succinic acid or sebacic acid, and a biobased alcohol and a biobased polyester.

A composition comprised of a component selected from the group consisting of a biobased bis-alkyl succinate and a biobased bis-alkyl sebacate, each derived, for example, from the esterification of biobased diacid such as succinic acid or sebacic acid, and a biobased alcohol and a biobased polyester.

Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.

Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.

Disclosed are a low-migration hindered phenol antioxidant compound, a preparation method and a composition. During production, processing or use, polymers experience degradation due to factors such as light, oxygen and heat. The oxidation resistance thereof is often increased by adding one or more common antioxidants, thereby inhibiting and delaying the rate if oxidative degradation thereof. The structures of traditional hindered phenolic antioxidant compounds migrate in polymers. The hindered phenolic antioxidant compound of the present invention has more hindered phenol units, and can achieve the objectives of low extraction and low migration.

Disclosed are a low-migration hindered phenol antioxidant compound, a preparation method and a composition. During production, processing or use, polymers experience degradation due to factors such as light, oxygen and heat. The oxidation resistance thereof is often increased by adding one or more common antioxidants, thereby inhibiting and delaying the rate if oxidative degradation thereof. The structures of traditional hindered phenolic antioxidant compounds migrate in polymers. The hindered phenolic antioxidant compound of the present invention has more hindered phenol units, and can achieve the objectives of low extraction and low migration.

The present invention provides a compound having an excellent efficacy for controlling pests. According to the present invention, a compound represented by formula (I) [wherein Q represents a group represented by Q1, or a group represented by Q2 (where • represents a binding site to a benzene ring), E represents a C5-C6 cycloalkenyl group and so on, L represents an oxygen atom or NH, a combination of R.sup.1 and n represents a combination where R.sup.1 represents a hydrogen atom, and n is 1, and so on, and R.sup.2 represents a methyl group and so on] or its N-oxide, or agriculturally acceptable salts thereof has an excellent efficacy for controlling pests.

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