Disclosed are compounds comprising chemically modified gamma-hydroxybutyrate (GHB), 2-hydroxytetrahydrofuran, and/or 1,4-butanediol, and salts of such compounds (GHB delivering compounds and salts thereof). Also disclosed are compositions comprising at least one GHB delivering compound, or a salt thereof, methods of making such compounds, and methods of using such GHB delivering compounds and compositions.

Provided herein are solid forms comprising (a) 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and (b) a coformer. Pharmaceutical compositions comprising the solid forms (e.g., cocrystals) and methods for treating, preventing and managing various disorders are also disclosed.

Provided herein are solid forms comprising (a) 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione and (b) a coformer. Pharmaceutical compositions comprising the solid forms (e.g., cocrystals) and methods for treating, preventing and managing various disorders are also disclosed.

A compound of Formula (I):

##STR00001##

or a pharmaceutically acceptable salt thereof, in which Ring X is a 3 to 7 membered monocyclic ring, at least one of R.sub.1, R.sub.2, R.sub.3, and R.sub.4 is OR.sub.5 or CH.sub.2OR.sub.5 and the other R.sub.1, R.sub.2, R.sub.3, and R.sub.4 each independently are halogen, OH, OR.sub.5, CH.sub.2OR.sub.5, CO.sub.2H, OC═OR.sub.6, (C═O)R.sub.6, R.sub.6, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, H, or absent. Also provided herein are therapeutic uses of the compound of Formula (I).

A compound with anti-drug resistant bacteria activity having the following formula (I): ##STR00001##
(I) is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

A compound with anti-drug resistant bacteria activity having the following formula (I): ##STR00001##
(I) is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

A compound with anti-drug resistant bacteria activity having the following formula (I): ##STR00001##
(I) is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

A compound with anti-drug resistant bacteria activity having the following formula (I):

##STR00001##

is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

A compound with anti-drug resistant bacteria activity having the following formula (I):

##STR00001##

is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

A compound with anti-drug resistant bacteria activity having the following formula (I):

##STR00001##

is disclosed. The methods of preparing the compound of formula (I) are also disclosed.