Described herein are nitrated lipids and methods of making and using the nitrated lipids.

The present invention relates to the preparation of -substituted -amino carboxylic acids, preferably in enantiomerically enriched or even enantiomerically pure form, by a one-pot conversion of a -substituted -nitro dicarboxylic acid ester or of a -substituted -nitro dicarboxylate of general formula to a -substituted -nitro carboxylic acid and a subsequent reduction of the -nitro group to an amine group. In particular, the present invention relates to the preparation of (S)-pregabalin. In addition, the formation of enantiomerically enriched -substituted -amino carboxylic acids and -substituted -nitronate carboxylic acid salts are also described.

The present invention relates to the preparation of -substituted -amino carboxylic acids, preferably in enantiomerically enriched or even enantiomerically pure form, by a one-pot conversion of a -substituted -nitro dicarboxylic acid ester or of a -substituted -nitro dicarboxylate of general formula to a -substituted -nitro carboxylic acid and a subsequent reduction of the -nitro group to an amine group. In particular, the present invention relates to the preparation of (S)-pregabalin. In addition, the formation of enantiomerically enriched -substituted -amino carboxylic acids and -substituted -nitronate carboxylic acid salts are also described.

A method of manufacturing nitrone compounds is provided. The method includes: providing a nitro compound; and performing a photoreaction of the nitro compound, a catalyst and an additive under visible light to obtain the nitrone compound.

A method of manufacturing nitrone compounds is provided. The method includes: providing a nitro compound; and performing a photoreaction of the nitro compound, a catalyst and an additive under visible light to obtain the nitrone compound.

Described herein are nitrated lipids and methods of making and using the nitrated lipids.

The present invention relates to the preparation of -substituted -amino carboxylic acids, preferably in enantiomerically enriched or even enantiomerically pure form, by a one-pot conversion of a -substituted -nitro dicarboxylic acid ester or of a -substituted -nitro dicarboxylate of general formula to a -substituted -nitro carboxylic acid and a subsequent reduction of the -nitro group to an amine group. In particular, the present invention relates to the preparation of (S)-pregabalin. In addition, the formation of enantiomerically enriched -substituted -amino carboxylic acids and -substituted -nitronate carboxylic acid salts are also described.

The present invention relates to the preparation of -substituted -amino carboxylic acids, preferably in enantiomerically enriched or even enantiomerically pure form, by a one-pot conversion of a -substituted -nitro dicarboxylic acid ester or of a -substituted -nitro dicarboxylate of general formula to a -substituted -nitro carboxylic acid and a subsequent reduction of the -nitro group to an amine group. In particular, the present invention relates to the preparation of (S)-pregabalin. In addition, the formation of enantiomerically enriched -substituted -amino carboxylic acids and -substituted -nitronate carboxylic acid salts are also described.

A method of manufacturing nitrone compounds is provided. The method includes: providing a nitro compound; and performing a photoreaction of the nitro compound, a catalyst and an additive under visible light to obtain the nitrone compound.

A method of manufacturing nitrone compounds is provided. The method includes: providing a nitro compound; and performing a photoreaction of the nitro compound, a catalyst and an additive under visible light to obtain the nitrone compound.