Processes for stereoselective preparation of a chiral alcohol or a chiral amine are described. The processes include reacting a first prochiral reactant selected from the group consisting of a ketone, an aldehyde, and an imine, with a second reactant that includes a Grignard reagent, in the presence of a chiral trans-diamine of formula (1) as defined herein: ##STR00001##

Processes for stereoselective preparation of a chiral alcohol or a chiral amine are described. The processes include reacting a first prochiral reactant selected from the group consisting of a ketone, an aldehyde, and an imine, with a second reactant that includes a Grignard reagent, in the presence of a chiral trans-diamine of formula (1) as defined herein: ##STR00001##

This disclosure relates bis-amine compounds disclosed herein and uses related to CXCR4 inhibition. In certain embodiments, the compounds have formula (I), salts, derivatives, and prodrugs thereof wherein, A is a bridging aryl or heterocyclyl and R.sup.1 and R.sup.2 are further disclosed herein. In certain embodiments, the disclosure contemplates pharmaceutical compositions comprising compounds disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing CXCR4 related diseases or conditions by administering an effective amount of a compound disclosed herein to a subject in need thereof.

A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: ##STR00001## wherein X is a divalent linking moiety; and R.sup.1-R.sup.10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R.sup.3 or R.sup.8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen.

A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of: ##STR00001## wherein X is a divalent linking moiety; and R.sup.1-R.sup.10 are each individually H, optionally-substituted alkyl, optionally-substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, halogen, amino, or hydroxy, provided that at least one of R.sup.3 or R.sup.8 is an optionally-substituted alkyl, a substituted alkoxy, optionally-substituted aryl, optionally-substituted cycloalkyl, optionally-substituted heterocyclic, or halogen.

A novel compound for a capping layer, and an organic light emitting device containing the same are disclosed. The compound for a capping layer is represented by Formula 1 below:

##STR00001##

A novel compound for a capping layer, and an organic light emitting device containing the same are disclosed. The compound for a capping layer is represented by Formula 1 below:

##STR00001##

Provided is a rubber composition that has better weather resistance than conventional rubber compositions and can inhibit surface discoloration of a rubber article. The rubber composition contains at least one rubber component selected from natural rubber and diene-based synthetic rubbers and, blended therewith, at least one amine compound represented by formula (I) shown below. In formula (I), R.sup.1 and R.sup.2 each represent, independently of one another, an alkyl group having a carbon number of 1-10, an aralkyl group, or a phenyl group, and A represents an alkylene group having a carbon number of 6-30 that may include an interposed phenylene group. ##STR00001##

Provided is a rubber composition that has better weather resistance than conventional rubber compositions and can inhibit surface discoloration of a rubber article. The rubber composition contains at least one rubber component selected from natural rubber and diene-based synthetic rubbers and, blended therewith, at least one amine compound represented by formula (I) shown below. In formula (I), R.sup.1 and R.sup.2 each represent, independently of one another, an alkyl group having a carbon number of 1-10, an aralkyl group, or a phenyl group, and A represents an alkylene group having a carbon number of 6-30 that may include an interposed phenylene group. ##STR00001##

Provided is a rubber composition that has better weather resistance than conventional rubber compositions and can inhibit rubber article surface discoloration. The rubber composition contains at least one rubber component selected from natural rubber and diene-based synthetic rubbers and, blended therewith, at least one bisphenyldiamine compound represented by formula (I). In formula (I), R.sup.1, R.sup.2, R.sup.5, and R.sup.6 each represent, independently of one another, a hydrogen atom, an alkyl group having a carbon number of 1-10, or a phenyl group, but R.sup.1 and R.sup.2 do not both simultaneously represent a hydrogen atom and R.sup.5 and R.sup.6 do not both simultaneously represent a hydrogen atom, R.sup.3 and R.sup.4 each represent, independently of one another, an alkyl group having a carbon number of 1-8 or an aralkyl group, A represents an alkylene group having a carbon number of 1-12, and l, m, and n each represent an integer of 0 or 1. ##STR00001##