An endoscope system sets a hardness variation of a thick flexible tube portion and a hardness variation of a thin flexible tube portion such that their respective ratios against base hardness are constant, and as each flexible tube portion becomes thicker, the hardness variation increases and an endoscope with a relatively thin flexible tube portion has a smaller hardness variation. This makes it possible to avoid situations like an endoscope with a thick flexible tube portion lacking hardness or an endoscope with a thin flexible tube portion becoming too hard, and makes it possible to perform optimum insertion operation in accordance with the thickness of a flexible tube.

A tissue visualization and modification device may include a rigid access body having a longitudinal axis, an internal passageway extending from the proximal end to the distal end, and an access body imaging sensor positioned on the distal end of the body and protruding inward beyond an inner wall into the internal passageway. An elongated member may be slidably positioned within the rigid access body. The elongated member may include, when viewed substantially along the longitudinal axis, a dissection electrode in the shape of a semicircle, an irrigation channel positioned within the semicircle, an aspiration channel positioned partially within the semicircle and adjacent the irrigation channel, first and second illumination elements positioned adjacent the respective tips of the semicircle and an elongated member imaging sensor positioned adjacent the aspiration channel.

A multifunctional visualization instrument is provided that, in certain embodiments, includes a body having a proximal end and a distal end. The multifunctional visualization instrument includes a display screen on the body and a camera stick at the distal end of the body and comprising an arm and a camera. The arm of the camera stick is sized to fit within a channel of a removable laryngoscope blade. The multifunctional visualization instrument includes a port on a surface of the laryngoscope, configured to mate with an introducer and a steering input for steering the introducer, displayed on the display screen simultaneously with an image of the patient captured by the camera.

A medical system comprising a guidewire that is connectable to a catheter is described. The guidewire has a housing connected to the distal end of a core wire. A printed circuit board (PCB) electrically connected to a camera chip resides in the housing. An atraumatic lens is supported by the housing with the camera chip residing between the atraumatic lens and the housing so that light rays entering the atraumatic lens are refracted to a focal plane aligned along a distal face of the camera chip. A proximal connector powered by a controller is wired to a visual display. With the proximal end of the guidewire connected to the proximal connector, the controller provides electrical power to the camera chip via a power cable extending along the core wire to the PCB. The catheter has an axially-extending primary lumen and a plurality of optical fibers extending to respective light-emitting lenses. During a medical procedure, the guidewire is first inserted into the vasculature of a patient. The guidewire is then received in the primary lumen of the catheter to connect the catheter to the guidewire. Then, the guidewire is connected to the proximal connector to enable the controller to provide electrical power to the camera chip. This provides the surgeon with a visual image of the vasculature illuminated by the light-emitting lenses of the catheter during the medical procedure.

This invention relates generally to a diagnostic and therapeutic device. According to some aspects of the invention, the device may be composed of a flexible sheet that is wrapped around the endoscope shaft to form a flexible overtube. The overtube may include an inflatable positioning ring that may be inflated after placement of the overtube just proximal to the tip of the endoscope or colonoscope to secure the position of the overtube within the body cavity. The overtube also may include an inflatable sealing band within the internal surface of the overtube that when inflated create a seal around the endoscope shaft. According to other aspects of the invention, the device may be a catheter with an occlusion balloon at its free end portion that is carried by the overtube and extends beyond the tip of the endoscope. Inflation of the positioning ring, sealing band and occlusion balloon may define an examination compartment within the body cavity at the tip of the endoscope. The examination compartment may be filled with air, or with water, depending on applications. In addition the examination compartment can be thoroughly lavaged using the irrigation tube system.

A rigid endoscope set according to the invention includes a rigid endoscope body having a first insertion portion inserted into a subject, a first channel provided in the first insertion portion and an ultrasound observation section disposed at a distal end of the first insertion portion to observe the subject, a treatment instrument guide having a second insertion portion configured to be inserted into or removed from the first channel and a second channel provided in the second insertion portion, and an optical telescope having a needle portion configured to be insertable into or removable from the second channel, a third insertion portion configured to be insertable into or removable from the first channel instead of the treatment instrument guide and an optical observation section disposed at a distal end of the third insertion portion to observe the subject.

Tools and systems for the delivery of medical devices or components, and more specifically, to tools and systems that assist or facilitate the delivery of one or more medical device or component over, onto, into, or against, another medical device or component are provided. More specifically, delivery tools and systems for the placement of an endoscopic device over, onto, into, or against, another instrument or endoscope are provided.

A falloposcope is described, and a method of screening a patient for fallopian tube and/or ovarian cancer with the falloposcope. The falloposcope can perform optical imaging, including fluorescence imaging and/or optical coherence tomography (OCT), and optionally include a channel for a sampling wire, within a diameter of about 0.7 millimeter. The method includes inserting the falloposcope through a lumen of vagina, cervix, uterus, and fallopian tube so a tip of the falloposcope is in proximity to a first fallopian tube or ovary of the patient; providing fluorescence stimulus wavelength through an illumination fiber of the falloposcope while imaging light at fluorescence emission wavelength through a coherent fiber bundle to form fluorescence emissions images; and determining suspect tissue. Then the sampling wire is used to collect cells from the suspect tissue for karyotype and other analysis.

Exemplary embodiments of devices and method for affecting at least one anatomical tissue can be provided. A configuration can be provided that includes a structure which is expandable (i) having and/or (ii) forming at least one opening or a working space through which the anatomical tissue(s) is placed in the structure. For example, the structure, prior to being expanding, can have at least one partially rigid portion. In addition, or as an alternative, upon a partial or complete expansion thereof, the structure can be controllable to have a plurality of shapes. Further, the structure can be controllable to provide the working space with multiple shapes and/or multiple sizes.

A solution is proposed for imaging a body-part (103) of a patient (106) with an endoscopic system (100). A corresponding method (500) comprises acquiring (509-515) two sequences of images with different probes (127n,127b), of corresponding endoscopic units (115m,115b), that are movable therebetween. Corresponding images of each pair in the two sequences are registered (518-584), for example, according to corresponding motions of their probes (127n,127b) that are estimated independently each according to the corresponding images. A method (800) is also proposed for training a neural network (439) that may be used to register the images. Corresponding computer programs (400;700) and computer program products for operating the endoscopic system (100) and for training the neural network (439) are proposed. Moreover, corresponding endoscopic system (100) for imaging the body-part (103), endoscopic equipment (115b) comprising one of the endoscopic units (115m,115b), computing device (242b) for operating the endoscopic system (100) and computing system (600) for training the neural network (439) are proposed. A surgical method, a diagnostic method and a therapeutic method based on the same solution are further proposed.