The present invention discloses a system to control a movement of a magnetic capsule using an external magnet control system. The external magnet control system includes more than one external magnetic balls, and at least one external magnetic ball can be moved freely in five degrees of the freedom.

A computer-implemented method of internally printing a biostructure on a damaged area of a patient. The method includes: assembling a first bioprinter capsule and a first cartridge capsule to form an assembled bioprinter internally within the patient based, at least in part, on directing one or more magnetic fields towards a first bioprinter capsule and a first cartridge capsule, moving the assembled bioprinter to the internally damaged area of the patient based, at least in part, on altering the one or more external magnetic fields directed towards the assembled bioprinter, and printing, via the assembled bioprinter, a first biostructure onto the internally damaged area of the patient based, at least in part, on altering the one or more external magnetic fields directed towards the assembled bioprinter, wherein the one or more external magnetic fields are sequentially altered to incrementally move the assembled bioprinter along at least one plane.

Method for extending battery life and a capsule endoscope using the method are disclosed. According to this method, sub-tasks associated with capturing one image using the capsule endoscope when the capsule endoscope moves through a human GI (gastrointestinal) tract after being ingested by a human subject are identified. The capsule endoscope is capable of capturing an image sequence at a first frame period, and at least two sub-tasks are performed with partial or full overlap. One or more images are captured at a second frame period by performing sub-task spreading, where the sub-task spreading spreads the sub-tasks over time to reduce or avoid the partial or full overlap for said at least two sub-tasks so as to reduce a sub-task peak current or peak current duration. The second frame period is longer than the first frame period.

A method of ion imaging is disclosed that includes automatically sampling a plurality of different locations on a sample using a front device which is arranged and adapted to generate aerosol, smoke or vapour from the sample. Mass spectral data and/or ion mobility data corresponding to each location is obtained and the obtained mass spectral data and/or ion mobility data is used to construct, train or improved a sample classification model.

A method is disclosed comprising providing a biological sample on a swab, directing a spray of charged droplets onto a surface of the swab in order to generate a plurality of analyte ions, and analysing the analyte ions.

An ex-vivo communication module configured for communicating with a swallowable in-vivo device. The communication module comprises a receiving unit operating at a first frequency range and configured for receiving signals from the in-vivo device, and a transmitting unit operating at a second frequency range, different from the first frequency range and configured for transmitting signals to the in-vivo device. The transmitting unit is also configured for serving as a secondary receiving unit, receiving signals from the in-vivo device.

A capsule endoscope device, system and method for dynamically adjusting a color illumination spectrum. A plurality of different color groups of LEDs may emit light, recorded by an image sensor, corresponding to a plurality of different respective wavelength subranges. A driving circuit may send a driving current to independently activate each different color group of LEDs during entirely or partially non-overlapping time pulses. A single color group of LEDs is independently activated at any one time, and the plurality of different color groups of LEDs are sequentially activated in successive time pulses to simulate a white light or multi-color illumination spectrum over a plurality of the time pulses. The activation pattern of the color groups of LEDs may be dynamically adjusted, in real-time, to achieve a flexible and customizable illumination spectrum ideal for imaging a variety of different environments e.g., in the GI tract.

A method and apparatus for sharpening gastrointestinal (GI) images are disclosed. A target distance between the target region and the imaging apparatus is determined for a target region in the regular image. One or more filter parameters of a de-blurring filter are selected from stored filter parameters according to the target distance. A processed target region is generated by applying the de-blurring filter to the target region to improve sharpness of the target region. A method for characterizing an imaging apparatus is also disclosed. The imaging apparatus is placed under a controlled environment. Test pictures for one or more test patterns are captured at multiple test distances in a range including a focus distance using the imaging apparatus. One or more parameters associated a target point spread function are determined from each test picture for characterizing image formation of the imaging apparatus at the selected distance.

Passive location of an emitter is achieved by sensing a signal propagated from the emitter at multiple sensing locations and determining its phase at each sensing location. A three-dimensional region is searched to find an emitter location for which phase estimates of the signal at the emitter location are in good agreement among the sensing locations. An iterative search from a set of starting points in the region may be performed. The region may be subdivided and each region searched in parallel using multiple processors in parallel. Phase at the sensing locations may be determined locally, using synchronized clocks at the sensing locations, or at a common receiver. In the latter case, signal propagation time from the sensing location to the receiver location is taken into account. The emitter may be a wireless endoscopy capsule, for example.

Systems and methods described herein use near field communications to locate a radiating transponder, such as a pill swallowed by a patient. The system can be triggered to turn on and transmit a waveform to a set of antennas attached to, coupled with, or near the patient. The magnetic field emitted by the transponder can be measured by the receiving antennas, for example, using principles of mutual inductance. The differential phase and/or time shifts between the antennas can contain sufficient information to find the location of the transponder and optionally its orientation relative to body coordinates. The system can display the location and/or orientation of the transponder. Further, the pill can include a reservoir to deliver a payload at a particular site of the patient's body based at least in part on the determined location.