Improved fluoresced imaging (FI) and other sensor data imaging processes, devices, and systems are provided to enhance use of endoscopes with FI and visible light capabilities. A first optical device is provided for endoscopy imaging in a white light and a fluoresced light mode with an image sensor assembly including one or more image sensors. A mechanism in the first optical device to automatically adjust the focus of the first optical device wherein the automatic focus adjustment compensates for a chromatic focal difference between the white light image and the fluoresced light image caused by the dispersive or diffractive properties of the optical materials or optical design employed in the construction of the first or second optical devices, or both. Adjustment mechanisms are provided using liquid lenses or repositioning sensors. The design may be integrated with a scope or detachable.

An objective system of a medical scope including an optical filter is disclosed. The optical filter includes a light incident side and a light exit side, a central region around an optical axis, and a peripheral region and is designed as an aperture with a single optical axis for white light and fluorescence light. The optical filter includes a first transmission zone for a transmittance of a first wavelength band and a second transmission zone for a transmittance of a second wavelength band at least partially different from the first wavelength band. At least one of the two transmission zones includes a filter coating. As a result, when both white light and fluorescence light pass the optical filter, a light beam cone of the fluorescence light has a larger diameter than a light beam cone of white light or vice versa. The invention also discloses a related endoscope.

The system includes a catheter with an internal optical fiber that carries an optical beam and an optical element, which reflects the optical beam substantially orthogonal to a rotational axis of the catheter and is coupled to the end of the optical fiber. A motor drive unit (MDU) is coupled to the catheter, wherein the MDU comprises: a rotary collimator; a catheter interface, which couples the optical fiber to the rotary collimator; and a drive motor, which rotates the rotary collimator. The MDU also includes a first dichroic mirror that combines optical paths for a fluorescence-lifetime imaging (FLIm) system and an optical coherence tomography system into a single optical path, which is coupled to the optical fiber through the rotary collimator and the catheter interface. The MDU additionally includes a multispectral detector for the FLIm system, which is electrically coupled to a data acquisition unit forthe FLIm imagin system.

Image rotation in an endoscopic laser mapping imaging system is described. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a rotation sensor for detecting an angle of rotation of a lumen relative to a handpiece of an endoscope. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter is a laser mapping pattern.

A plurality of devices that provide examination/diagnosis and/or treatment benefits to a patient are presented. The device including a plurality of light sources that provide for the emission of light in a plurality of wavelength ranges, wherein the plurality of light sources are activated by a sensor, configured to determine a proximity of the device to a patient, to control an application of a voltage to selected one of the plurality of light sources for a predetermined time period.

A body-insertable apparatus includes an image sensor including a first pixel configured to receive light of a first wavelength band and to generate a first signal, a second pixel configured to receive light of a second wavelength band different from the first wavelength band and to generate a second signal, and a third pixel configured to receive a third wavelength band different from the first and second wavelength bands and to generate a third signal; and a processor comprising hardware, the processor being configured to allocate part of at least one of the first signal and the second signal to the third signal, when first light is received on the first and second pixels, the first light including at least one of the light of the first wavelength band and the light of the second wavelength band and excluding the light of the third wavelength band.

An endoscope system 10 includes: an image acquiring unit 54 that acquires an endoscope image obtained by imaging an observation target; a baseline information calculating unit 86 that calculates baseline information by using the endoscope image or a display endoscope image 101 generated by using the endoscope image, the baseline information being information about light scattering characteristics or light absorbing characteristics of the observation target and information that is at least not dependent on particular biological information; an imaging scene determination unit 87 that determines the imaging scene by using the baseline information; and a condition setting unit 88 that sets a condition for imaging or image processing, by using a determination result of the imaging scene determination unit.

Systems, devices, and methods operate on a fluorescence image to ensure a white balance correctness of the fluorescence image; perform a color analysis of the fluorescence image, including: converting the fluorescence image to an HSV color space, comparing a saturation parameter of the first converted image to a first saturation threshold condition and comparing a value parameter of the first converted image to a first value threshold condition, wherein the first value and saturation threshold conditions are based on a correlation between a first color and the first bacterial fluorescence signature, and identifying areas of the fluorescence image where the saturation parameter satisfies the first saturation threshold condition and the first value parameter satisfies the value threshold condition, discard the identified areas which are smaller than a size threshold, and outline the remaining identified areas on the fluorescence image, thereby to generate an overlay image.

An exemplary apparatus for obtaining data for at least one portion within at least one luminal or hollow sample can be provided. For example, the apparatus can include a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the portion(s). The apparatus can also include a wavelength dispersive second arrangement, which can be configured to disperse the electromagnetic radiation(s). A housing can be provided with a shape of a pill, and enclosing the first and second arrangements.

A surgical access assembly comprises a trocar and a surgical instrument. The trocar comprises a housing and an access tube extending distally from the housing. The housing comprises a hollow light emitter. The housing and the access tube define a lumen extending through the housing and the access tube. The hollow light emitter is configured to project light in the lumen. The surgical instrument comprises an end effector and a shaft extending proximally from the end effector. The shaft comprises an optical receiver positioned within reach of the light from the hollow light emitter. The shaft further comprises a light guide extending from the optical receiver along at least a portion of the shaft toward the end effector.