Patent classifications
C07C251/76
Potent cytotoxic agent against human hepatocellular carcinoma cell line based on 2-aryl hydrazonopropanal pharmacophore
The invention is directed to 2-aryl hydrazonopropanals that exert anti-tumor activity and methods for using them to prevent, inhibit and treat cancer. It also involves anti-tumor compositions containing these 2-aryl hydrazonopropanals, and methods of treatment using these compositions.
Catalytic Hydrogenation Process for Preparing Pyrazoles
The present invention relates to a catalytic process for preparing pyrazoles comprising the step of cyclizing hydrazone substituted ?,?-unsaturated carbonyl compounds by reacting them with hydrogen in a reaction mixture comprising as components (a) a hydrogenation catalyst, (b) an acid selected from Br?nsted acids, ammonium salts of Br?nsted acids, and Lewis acids, (c) a protic solvent, and optionally (d) an aprotic solvent.
Catalytic Hydrogenation Process for Preparing Pyrazoles
The present invention relates to a catalytic process for preparing pyrazoles comprising the step of cyclizing hydrazone substituted ?,?-unsaturated carbonyl compounds by reacting them with hydrogen in a reaction mixture comprising as components (a) a hydrogenation catalyst, (b) an acid selected from Br?nsted acids, ammonium salts of Br?nsted acids, and Lewis acids, (c) a protic solvent, and optionally (d) an aprotic solvent.
Process for the Synthesis of Intermediates Useful for Preparing 1,3,4-Triazine Derivatives
A process for the synthesis of the intermediate useful for the preparation of 1,3,4-triazines, are disclosed.
Process for the Synthesis of Intermediates Useful for Preparing 1,3,4-Triazine Derivatives
A process for the synthesis of the intermediate useful for the preparation of 1,3,4-triazines, are disclosed.
ALKOXIDE COMPOUND, THIN FILM-FORMING STARTING MATERIAL, THIN FILM FORMATION METHOD, AND ALCOHOL COMPOUND
The alkoxide compound of the present invention is characteristically represented by the following general formula (I):
##STR00001##
ALKOXIDE COMPOUND, THIN FILM-FORMING STARTING MATERIAL, THIN FILM FORMATION METHOD, AND ALCOHOL COMPOUND
The alkoxide compound of the present invention is characteristically represented by the following general formula (I):
##STR00001##
Alkoxide compound, thin film-forming starting material, and thin film formation method
The alkoxide compound of the present invention is characteristically represented by the following general formula (I): ##STR00001##
Alkoxide compound, thin film-forming starting material, and thin film formation method
The alkoxide compound of the present invention is characteristically represented by the following general formula (I): ##STR00001##
PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITORS AND METHODS OF USE THEREOF
The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or disorder associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to prevent or reduce thrombosis and fibrosis, to promote thrombolysis, and to modulate lipid metabolism and treat diseases or disorders associated with elevated PAI-1, cholesterol, or lipid levels.