Patent classifications
C
CHEMISTRY; METALLURGY
Load children
C07
ORGANIC CHEMISTRY
Load children
C07D
HETEROCYCLIC COMPOUNDS
Load children
227/00
Heterocyclic compounds containing rings having one nitrogen atom as the only ring hetero atom, according to more than one of groups C07D203/00 - C07D225/00
Load children Filter patents View analytics View as hierarchy Open in page
C07D227/02
with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
Load children Filter patents View analytics View as hierarchy Open in page
C07D227/06
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Load children Filter patents View analytics View as hierarchy Open in page
C07D227/10
Nitrogen atoms not forming part of a nitro radical
Filter patents View analytics View as hierarchy Open in page

C07D227/10

2-Amino-3,5,5-Trifluoro-3,4,5,6-Tetrahydropyridines as BACE1 Inhibitors for Treatment of Alzheimer's Disease
20170066741 · 2017-03-09 · ·

The present invention is directed to novel inhibitors of the BACE1 enzyme. Separate aspects of the invention are directed to pharmaceutical compositions comprising said compounds and uses of the compounds to treat disorders for which the reduction of A deposits is beneficial such as Alzheimer's disease.