Patent classifications
C07D263/16
METHOD OF PREPARING SUBSTITUTED BICYCLO[1.1.1] PENTANES
A process for the preparation of a class of molecules, namely bicyclo[1.1.1]pentanes and derivatives thereof by reaction of [1.1.1]propellane with a variety of reagents under irradiation and/or in the presence of radical initiators to obtain bicyclo[1.1.1]pentanes asymmetrically substituted at position 1 and 3, which are useful as intermediates for the preparation of asymmetrically 1,3-disubstituted bicyclo[1.1.1]pentane derivatives and various physiologically active substances or materials containing these structures.
Azoline compounds
The present invention relates to azoline compounds of formula I ##STR00001##
wherein A, B.sup.1, B.sup.2, B.sup.3, G.sup.1, G.sup.2, X.sup.1, R.sup.1, R.sup.3a, R.sup.3b, R.sup.g1 and R.sup.g2 are as defined in the claims and the description. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.
Azoline compounds
The present invention relates to azoline compounds of formula I ##STR00001##
wherein A, B.sup.1, B.sup.2, B.sup.3, G.sup.1, G.sup.2, X.sup.1, R.sup.1, R.sup.3a, R.sup.3b, R.sup.g1 and R.sup.g2 are as defined in the claims and the description. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.
Benzoylglycine derivatives and methods of making and using same
Disclosed are compounds of formulae: ##STR00001##
and pharmaceutically acceptable salts thereof, wherein the variables, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, R.sub.17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.
Benzoylglycine derivatives and methods of making and using same
Disclosed are compounds of formulae: ##STR00001##
and pharmaceutically acceptable salts thereof, wherein the variables, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7, R.sub.11, R.sub.12, R.sub.13, R.sub.14, R.sub.15, R.sub.16, R.sub.17, n, and m are defined herein. These compounds are useful for treating Gram-negative bacteria infections. Also disclosed are methods of making these compounds.
AZOLINE COMPOUNDS
The present invention relates to azoline compounds of formula I
##STR00001##
wherein A, B.sup.1, B.sup.2, B.sup.3, G.sup.1, G.sup.2, X.sup.1, R.sup.1, R.sup.3a, R.sup.3b, R.sup.g1 and R.sup.g2 are as defined in the claims and the description. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.
AZOLINE COMPOUNDS
The present invention relates to azoline compounds of formula I
##STR00001##
wherein A, B.sup.1, B.sup.2, B.sup.3, G.sup.1, G.sup.2, X.sup.1, R.sup.1, R.sup.3a, R.sup.3b, R.sup.g1 and R.sup.g2 are as defined in the claims and the description. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.
CYCLOALKENYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS
The present invention provides compounds of formula (I):
##STR00001##
or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein W, X, n, s, t, and R.sup.a are as described herein. The present invention relates generally to selective inhibitors of histone deacetylase and to methods of making and using them.
CYCLOALKENYL HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS
The present invention provides compounds of formula (I):
##STR00001##
or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein W, X, n, s, t, and R.sup.a are as described herein. The present invention relates generally to selective inhibitors of histone deacetylase and to methods of making and using them.
Azoline compounds
The present invention relates to azoline compounds of formula I ##STR00001##
wherein A, B.sup.1, B.sup.2, B.sup.3, G.sup.1, G.sup.2, X.sup.1, R.sup.1, R.sup.3a, R.sup.3b, R.sup.g1 and R.sup.g2 are as defined in the claims and the description. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to plant propagation material and to an agricultural and a veterinary composition comprising said compounds.