C07D311/80

Nano-Emulsion Based Compositions, Methods for Their Preparation and Their Use in Delivery of Active Ingredients
20230225970 · 2023-07-20 ·

The present disclosure relates to compositions comprising an oil-in-water nano-emulsion dispersed in an external oil phase, methods for the preparation of such compositions as well as uses of such compositions, for example, for delivery of active ingredients to a subject. The methods comprise combining a first mixture comprising a liquid oil and a charged lipid with a second mixture that is an aqueous mixture comprising a film-forming thermoreversible emulsifier to prepare an oil-in-water nano-emulsion; and combining the oil-in-water nano-emulsion with a third mixture comprising a combination of solid lipids to prepare the composition.

Methods to purify cannabinoids

Various aspects of this patent document relate to the rapid purification of cannabinoids by vaporization and condensation.

Methods to purify cannabinoids

Various aspects of this patent document relate to the rapid purification of cannabinoids by vaporization and condensation.

METHODS OF PREPARING SYNTHETIC CANNABICHROMENE AND CANNABICITRAN AND DERIVATIVES THEREOF
20230219916 · 2023-07-13 ·

The present disclosure relates to the preparation of synthetic cannabinoid derivatives of Formulae I and II, and compositions made therefrom.

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EXTRACTION METHOD AND MIXTURE OF SUBSTANCES

A method for extraction, in which an extraction agent is used for dissolving at least one extraction material out of a substance. The extraction agent includes fatty acid ethyl ester and/or fatty acid methyl ester. In one embodiment the extraction agent is an omega-3 and/or omega-6 fatty acid, preferably EPA, DHA, DPA, ETA, 21:5n3 and/or SDA. In one embodiment the extraction agent includes at least 500 mg/g, preferably at least 700 mg/g of the fatty acid ethyl ester and/or of the fatty acid methyl ester. Expediently, the mixture of substances is a plant material, preferably hemp, and the extraction material is a cannabinoid, preferably CBD and/or THC.

EXTRACTION METHOD AND MIXTURE OF SUBSTANCES

A method for extraction, in which an extraction agent is used for dissolving at least one extraction material out of a substance. The extraction agent includes fatty acid ethyl ester and/or fatty acid methyl ester. In one embodiment the extraction agent is an omega-3 and/or omega-6 fatty acid, preferably EPA, DHA, DPA, ETA, 21:5n3 and/or SDA. In one embodiment the extraction agent includes at least 500 mg/g, preferably at least 700 mg/g of the fatty acid ethyl ester and/or of the fatty acid methyl ester. Expediently, the mixture of substances is a plant material, preferably hemp, and the extraction material is a cannabinoid, preferably CBD and/or THC.

SYSTEMS AND METHODS FOR INCREASING STABILITY OF DRONABINOL COMPOSITIONS
20230218534 · 2023-07-13 ·

Disclosed in certain embodiments is a system and method of providing a dronabinol oral solid dosage form with increased stability.

SYSTEMS AND METHODS FOR INCREASING STABILITY OF DRONABINOL COMPOSITIONS
20230218534 · 2023-07-13 ·

Disclosed in certain embodiments is a system and method of providing a dronabinol oral solid dosage form with increased stability.

METHOD FOR PRODUCING A PURIFIED CANNABACEAE BIOMASS EXTRACT

The present disclosure relates to a method for producing a purified cannabaceae biomass extract, wherein a crude alcoholic cannabaceae biomass extract comprising at least two cannabinoid compounds in an alcoholic solvent is circulating through a powdered layer of activated carbon and the purified cannabaceae biomass extract is recovered with a ratio of cannabinoid compounds in the purified cannabaceae biomass extract is higher than the ratio of the cannabinoid compounds in the crude alcoholic cannabaceae biomass extract.

Hybrid extraction process for cannabinoids and related methods

The present invention relates to methods for treating cannabis biomass in order to isolate tetrahydrocannabinolic acid (THCA). In another aspect, the present invention relates to a process that involves purification followed by extraction of cannabis biomass to isolate and improve yields of high-purity crystalline extracts.