Provided are transdermal microneedle-based devices for sensing the presence and concentration of analytes such as electrolytes, biomarkers, drugs, and proteins in interstitial fluid. Also provided are methods and systems to transmit the data obtained by wired or wireless connection to a receiver and to relay the data to the user or a clinician.

Vascular access assemblies are disclosed herein. In one example, a vascular access assembly comprises a proximal catheter, a distal catheter, and a junction positioned between the proximal and distal catheters and configured to position the proximal and distal catheters in fluid communication. The junction may comprise one or more sensors configured to obtain physiological and/or operational measurements. The junction may be configured to wirelessly transmit the measurements to one or more local or remote computing devices for monitoring by a caregiver.

Certain embodiments of the present disclosure relate to a monitoring device that includes a housing, contactless sensors coupled to the housing, and a processing device disposed in the housing. In at least one embodiment, the monitoring device is configured to measure pulse wave velocity in a subject.

Described are techniques, processes, devices, computer-readable media that enable provision of an indication of whether it is safe for a person with diabetes to participate in exercise while using a wearable drug delivery system. A processor may receive or obtain physiological data related to a condition of a wearer of the wearable drug delivery system and by evaluating an exercise model that uses inputs related to the physiological data to make the determination of whether it is safe to exercise and output an exercise safety signal. Modifications to the wearer's medication treatment plan and other actions may be based on an outputted exercise safety signal.

Embodiments herein relate to ear-wearable devices and systems that can detect a risk of infection in a device wearer. In a first aspect, an ear-wearable infection sensor device is included having a control circuit, a microphone, a sensor package, and an electroacoustic transducer, wherein the electroacoustic transducer is in electrical communication with the control circuit.

The ear-wearable infection sensor device can be configured to analyze data from the sensor package to determine physiological parameters of a device wearer and evaluate the physiological parameters to detect the risk of an infection. Other embodiments are also included herein.

An electronic battery-operated medical bracelet device that contains the technology to accurately detect collapse/fall or other medical emergencies, through the monitoring of the heart rate, oxygen saturation, heart rhythm, and patient input. The bracelet will also display the vital readings to the user if the readings return as abnormal, in an attempt to persuade the user to seek medical attention before it becomes worse. Once a medical emergency is detected, the device alerts surrounding people and paramedics of the emergency and distributes medical and personal information different for surrounding people and paramedics. This includes medical conditions, health insurance information, next of kin, etc. This information can be uploaded to the device's onboard memory drive and can share the information or steps to reach the information, through an onboard speaker system, Bluetooth pairing, and near-filled communication (NFC) to which paramedics have special access.

A tissue disorder monitoring system includes at least two electrodes constructed and arranged to obtain analog electrical signals from a patient. An amplifier amplifies the analog electrical signals. Filter structure filters the amplified analog electrical signal. An A/D converter converts the amplified and filtered analog electrical signals to digitized electrical signals. A microprocessor circuit is constructed and arranged to execute an application that analyzes the digitized electrical signals to identify and to determine treatment data including a specific location and/or propagation of disordered tissue within the patient. A transmitter transmits data in a wireless manner. A power supply powers the device. A method locating disordered tissue in a patient is also disclosed.

A portable healthcare system installed at a remote location having limited internet connectivity, the system comprising the following features: a camera configured to receive images/video of a patient, a point-of-care testing having medical devices configured to: receive samples from a body of the patient, determine parameters based on information from the samples, a pills dispenser, configured to dispense pills, a memory unit configured to store machine-readable instructions, and a processing unit operably connected with the memory unit, the processing unit obtaining the machine-readable instructions from the memory unit, and being configured by the machine-readable instructions to: run facial recognition based on the captured image of the patient and identify the patient, compare the determined parameters with predefined parameters, determine a health related information of the human body based on the comparison, and determine a medical condition of the patient, based on the health related information, connect a health professional, located at a distant location, through a augmented reality (AR) lens with the patient, record conversation between the patient and the health professional, and instruct the pills dispenser to dispense the pills, a communication means configured to establish a communication network which is configured to send the health related information, and the medical condition to user devices held by the patient, and/or health organizations, a user interface, configured to display the virtual health professional and facilitate interactive communication between the virtual health professional and the patient.

The invention proposes a new method for monitoring a health event in a mammal, comprising detecting at least one abnormal value within a series of values related to at least one biomarker, based on appropriate Z-scores.

Pressure sensing guidewire assemblies are described herein where the guidewire assembly may be comprised of an elongate guidewire body and multiple pressure sensors secured near or at a distal end of the guidewire body. The signals obtained from the guidewire connectors and aortic sensor modules may be synchronized to minimize signal acquisition delays. The signals may be further processed to equalize the pressure waveforms by shifting the connector waveform to align correctly with the aortic module waveform and improve output signals.