Ablation visualization and monitoring systems and methods are provided. In some embodiments, such methods comprise applying ablation energy to a tissue to form a lesion in the tissue, illuminating the tissue with a light to excite NADH in the tissue, wherein the tissue is illuminated in a radial direction, an axial direction, or both, monitoring a level of NADH fluorescence in the illuminated tissue to determine when the level of NADH fluorescence decreases from a base level in the beginning of the ablating to a predetermined lower level, and stopping ablation of the tissue when the level of NADH fluorescence reaches the predetermined lower level.

A dental hand-held device (100), including a curing device (101) for curing a dental restauration material (103) with light in a first wavelength range; and a fluorescence excitation device (105) for exciting fluorescence of dental substance (107) with light in a second wavelength range.

A combined MRI and radiotherapy apparatus comprises a radiotherapeutic source, an MRI system, a patient support, drive motors for the patient support arranged to adjust the position of the patient support while a patient is on the support, a control panel having a user-operable input interface for controlling the drive motors, and a display unit. A mounting arrangement for a display device comprises a transparent cover, a display panel held against a rear face of the cover so as to be visible through a front face of the cover, and a retaining structure for holding the display panel in place. The retaining structure comprises a chassis fixable in position relative to the cover, the chassis having at least one resilient finger extending therefrom alongside a rear face of the display panel, a part of which bears against the rear face of the display panel to resiliently urge the display panel against the rear face of the cover. The radiotherapeutic source, MRI system, patient support and the control panel will usually be located within an enclosed space, to confine the therapeutic radiation; a second control panel is provided outside the enclosed space, able to control at least the radiotherapy source.

There is provided a patient's cranial position monitoring and controlling device for controlling a magnetic resonance (MR) guided radiation source module via an MR-guided radiation controlling device connected to the patient's cranial position monitoring and controlling device and an MR-guided radiation system including a patient's cranial position monitoring and controlling device, which allows for better MR-imaging while allowing patient position monitoring close to the patient.

A surgical system includes a detector, comprising an array of pixels configured to detect light reflected by a surgical instrument and generate a first signal comprising a first dataset representative of a visible image of the surgical instrument. The surgical system also includes a processor configured to receive the first signal, generate a modified image of the surgical instrument that includes a control panel. The control panel includes one or more control elements representative of one or more operating parameters of the surgical instrument. The processor is further configured to receive an input to the control panel from a user, the input being effective to change one of the operating parameters. The processor is also configured to generate a command signal based on the input to change the one of the operating parameters.

A method of performing personalized neuromodulation on a subject is provided. The method includes acquiring functional magnetic resonance imaging (fMRI) data of a brain of the subject. The method also includes calculating functional connectivity of the brain between a voxel in a subcortical region of the brain and a voxel in a cortical region of the brain, based on the fMRI data. The method also includes identifying a target location in the brain to be targeted by neuromodulation based on the calculated functional connectivity.

The apparatus and method for hemostasis that informs the provider as to whether the appropriate magnitude of pressure is being applied to a puncture site on a patient. A visual pulse indicator can visually convey whether or not there is proper blood flow at the puncture site based on the pulsing motion encountered by the visual pulse indicator on the puncture site. The visual pulse indicator can potentially factor in a variety of different input parameters in displaying information that is useful to providers.

A radiation therapy system comprising a therapeutic radiation system (e.g., an MV X-ray source, and/or a linac) and a co-planar imaging system (e.g., a kV X-ray system) on a fast rotating ring gantry frame. The therapeutic radiation system and the imaging system are separated by a gantry angle, and the gantry frame may rotate in a direction such that the imaging system leads the MV system. The radiation sources of both the therapeutic and imaging radiation systems are each collimated by a dynamic multi-leaf collimator (DMLC) disposed in the beam path of the MV X-ray source and the kV X-ray source, respectively. In one variation, the imaging system identifies patient tumor(s) positions in real-time. The DMLC for the imaging radiation source limits the kV X-ray beam spread to the tumor(s) and/or immediate tumor regions, and helps to reduce irradiation of healthy tissue (e.g., reduce the dose-area product).

Embodiments of the present disclosure relate to techniques for neuromodulation delivery. Based on image data acquired from the subject, control parameters controlling energy application of neuromodulating energy may be dynamically changed during the course of the delivery to maintain desired characteristics of the neuromodulating energy. For example, the beam of the neuromodulating energy may be dynamically adjusted to account for movement of an organ during breathing. In another embodiment, a desired region of interest is identified within the subject based on a trained neural network and the acquired image data.

Methods for generating multiple orthodontic treatment options for a digital 3D model of teeth in malocclusion. The method generates a plurality of different orthodontic treatment plans for the teeth and displays in a user interface the digital 3D model of teeth in malocclusion with a visual indication of each of the plurality of different orthodontic treatment plans. The visual indication of the treatment plans can be overlaid on the digital 3D model of teeth in malocclusion and possibly include aligners, brackets, or a combination of aligners and brackets. A doctor, technician, or other user can then select one of the treatment plans for a particular patient.