To provide objective indications of the progression of peripheral neuropathy of patients, a transmitter apparatus is utilized to produce reproducible pulse signals to specified locations on the human body to determine a minimum level of stimulation necessary to elicit a consciously detectable sensation through the generation of a series of pulse signals of varying intensities, and the recordation of the number of pulse signals felt by the patient. Moreover, the nerve velocity of the patient is additionally determined for a patient via the transmitter apparatus and a receiver apparatus detecting body-signals passing along a nerve within the patient and corresponding to the pulse signals applied to the patient. The results of these tests are recorded over time, thereby enabling generation of patient-specific models indicative of the progression of the patient's peripheral neuropathy over time.

Devices for determining one or more corneal biomechanical properties are described herein which, in some embodiments, exhibit the versatility for continuous and intermittent patient monitoring. In some embodiments, a device comprises at least one self-sensing cantilever calibrated against a control of known biomechanical properties, wherein the self-sensing cantilever is coupled to a base configured to position the self-sensing cantilever adjacent to a corneal surface.

A system for characterizing tissue includes a probe that delivers a continuous and periodic mechanical vibration to a tissue of a subject; an ultrasound emitter that emits a sequence of ultrasound shots and an ultrasound receiver that receives corresponding echo signals to track how the tissue is moved by the periodic mechanical vibration delivered to the tissue; and a control module programmed to provide homogeneity information to an operator of the system, the homogeneity information being determined from at least some of the echo signals and being representative of the ability of the tissue to transmit elastic waves and of the homogeneity of the tissue with respect to the propagation of elastic waves.

Systems and methods for neurofeedback-triggered therapy for neurological conditions in accordance with embodiments of the invention are illustrated. One embodiment includes a neurofeedback-triggered therapy system, including a plurality of vibrotactile stimulators, a brain activity recorder, and a controller, including a processor, and a memory, the memory containing a neurofeedback application, where in order to condition a user to reduce the symptoms of a neurological condition on demand triggered by upregulating sensorimotor rhythm (SMR) activity, the neurofeedback application directs the processor to obtain brain activity data from the brain activity recorder, identify sensorimotor rhythm (SMR) spindles in the brain activity data, and provide vibrotactile Coordinated Reset (vCR) stimulation to a user using the plurality of vibrotactile stimulators when SMR spindles are identified, where the vCR stimulation reduces the symptoms of a neurological condition of the user.

A middle ear sound transmission characteristics evaluation system includes a probe; a measuring probe that includes an actuator that vibrates the probe and a force sensor that outputs a voltage in accordance with a reaction force exerted to the actuator when a tip of the probe is brought into contact with ossicles; an electrode that is installed on or near a round window and detects a potential value of a cochlear microphonic when vibration is applied to the ossicles by the probe; a database that stores a sensor voltage value output by the force sensor before surgical treatment, the potential value detected by the electrode, and surgical details; and a surgical details proposing unit that proposes selected surgical details on the basis of the magnitude of at least one of the sensor voltage value and the potential value measured before surgery with reference to the database.

Described here are systems and methods for a robust magnetic resonance elastography (“MRE”) imaging platform for rapid dynamic 3D MRE imaging. The imaging platform includes an MRE pulse sequence and advanced image reconstruction framework that work synergistically in order to greatly expand the domains where MRE can be deployed successfully.

The present invention is directed to a sensor device detecting movement of mouth or tongue associated with bruxism and/or sleep apnea. The present invention is also directed to a system for treating sleep apnea in a patient in need thereof, comprising a sensing component and a stimulation component, the sensing component comprising one or more wireless sensors for collecting one or more vital signs of the patient and/or tongue muscle movements of the patient, the sensing component being in wireless communication with a control system, and wherein the stimulation component comprises (i) an implantable body configured to deliver energy to one of a nerve or muscle, and (ii) a wearable appliance inductively coupled to the implanted body, the wearable portion configured to receive signals from the control system, wherein the sensing component comprises the sensor device of the present invention.

An intraocular pressure measurement arrangement is disclosed for measuring pressure of an eye of a patient. The arrangement can include at least one source for producing mechanical waves of several frequencies from a distance to the eye of the patient to generate at least one surface wave to the eye, a detector for detecting at least one surface wave from a distance from the eye to extract surface wave information, and a device for determining pressure information of the eye based on the surface wave information.

A peripheral device for regulating neural correlates of arousal and emotion regulation to be worn or held against the body is disclosed. The device can be triggered by either physiological signs or manual intervention and produces cutaneous signals such as vibration or electricity using novel combinations of physiologically reactive frequencies without effort on the part of the user. One embodiment includes combining sensors that measure changes in physiological signals of stress such as speech rate and pitch, galvanic skin response, or heart rate variability, and, using a machine learning algorithm on personalized data, can determine whether these changes are likely to benefit from regulation. If they are outside an idiosyncratic predetermined range, the device produces stimulation and the person will feel regulated if they are touching/wearing the device, or can choose to use the device if it is not currently being touched or worn.

A shoe-type device and a control method of the shoe-type device are disclosed. A control method of a shoe-type device including an actuator and at least one sensor includes estimating a posture of a user wearing the shoe-type device based on sensor data output from the sensor, and controlling the actuator based on the estimated posture of the user.