Tactile sensing devices, systems, and methods to image a target tissue location are disclosed. When force is applied to the tactile sensing device, voltage data is detected and visualized on a screen, indicating the target tissue location.

According to some embodiments there is provided a wearable device for breast screening, comprising: at least one breast-contacting member shaped to contact a surface of a breast, the member comprising an array of force applying units and an array of sensors configured for sensing at least one parameter in response to force applied by the force applying units; the force applying units and the sensors disposed on or within the breast-contacting member and positioned to contact a surface of the breast; a memory storing one or more patterns suitable to detect a lump underlying the surface; wherein the pattern comprises a sequence of forces that vary spatially and/or vary in time; a controller configured for: reading data from the memory to control application of force; communicating with the sensors to receive signals associated with the at least one parameter sensed in response to the application of force; and to process the received signals to detect a lump.

A wearable monitoring device is disclosed. The wearable monitoring device may include: a housing, opened from at least one side; a sensing unit attached to a movable plate; and a controller. The movable plate may be connected to one or more spring-like elements, allowing the movable plate to move with respect to the housing so that when the one or more spring-like elements are extended, the sensing unit protrudes from the open side of the housing and when the one or more spring-like elements are compressed the sensing unit and the movable plate are retracted towards an internal space in the housing.

A back brace is configured to be worn by a patient for treating spinal deformations. The back brace has at least one pressure sensor configured to be attached to the back brace at a point of pressure with the body of a patient, and at least one strap configured to be tightened for adjusting a pressure at the point of pressure. A control unit is configured to be attached to one of an outside of the back brace and inside a cavity formed in the back brace. The control unit is configured for (a) processing signals from the at least one pressure sensor, (b) communicating with at least one external computing apparatus, (c) informing and guiding in real time and incentivizing a patient to more efficiently wear the back brace by at least providing indications to the patient for tightening the at least one strap by comparing a pressure value provided by the at least one pressure sensor with at least one calibration value, and (d) enabling a doctor to more efficiently monitor, intervene, and manage the patient and treatment in real time.

A miniature quantitative optical coherence elastography system with an integrated Fabry-Perot force sensor for in situ elasticity measurement of biological tissue is provided. The technique has great potential for biomechanics modeling and clinical diagnosis. The qOCE system contains a fiber-optic probe that exerts a compressive force to deform tissue at the tip of the probe. Using the space-division multiplexed optical coherence tomography signal detected by a spectral domain optical coherence tomography engine, probe deformation in proportion to the force applied is quantified, as well as the tissue deformation corresponding to the external stimulus. Simultaneous measurement of force and displacement allows for calculation of Young's modulus from the biological tissue. The provided system has had its effectiveness validated on tissue mimicking phantoms, as well as biological tissues, with the advantages of being minimal invasive and also not requiring the use of external agents or substantial pre-measuring preparation.

The present invention relates to a stimulus information compiling method for tests, characterized in that, the stimulus information compiling method comprises the following steps: selecting and using stimulus information which follows a statistics-normal distribution and is analyzed and measured by validity to form a stimulus information database (Q); reasonably setting at least one stimulus information to be a test including at least one test sequence, for a subject to make a selection according to his or her personal interests; comparing a test score of the subject with that of a valid sample person in a normal distribution model, thereby confirming the distribution of the subject in each cognitive dimension. The present invention compares a test score of the subject with that of a valid sample person in a normal distribution model, thereby confirming the test result of the subject.

The present disclosure provides an optical palpation device for evaluating a mechanical property of a sample material. The device comprises a body having a sensing portion and a sensing layer positioned at the sensing portion of the body and having a sensing surface positioned for direct or indirect contact with a surface area of the sample material. The sensing layer is deformable and has a predetermined deformation-dependent optical property. The device further comprises a light detector positioned to detect light transmitted through at least a portion of the sensing layer. The optical palpation device is arranged such that, when the sensing surface of the sensing layer is in direct or indirect contact with the surface area of the sample material and a pressure is applied through both the sensing layer and at least a portion of the surface area of the sample material, because of the predetermined deformation or pressure-dependent optical property of the sensing layer the mechanical property of the sample material is measurable by detecting the light that transmitted through at least a portion of the sensing layer.

Embodiments of the present systems and methods may provide techniques that are applicable to a variety of imaging modalities and that utilize prior knowledge of the dynamics of a physiological system to analytically generate augmented samples for machine learning. For example, in an embodiment, a method implemented in a computer comprising a processor, memory accessible by the processor, and computer program instructions stored in the memory and executable by the processor, the method may comprise generating a transform for an image of tissue based on deformation of the tissue under compression, obtaining an image of tissue using an imaging modality, and generating an output image by transforming the image of the tissue using the transform.

A method for the objective determination of capillary refill behavior on a human body surface in which a spatially and spectrally resolved optical detection is carried out by at least one detector device (1) at a skin surface area (2) having a predefined areal size and outer contour. Subsequently a predefined pressure p constant over the skin surface area (2) is exerted over a predefined time t1; and the pressure effect is ended after expiry of this time t1. The spatially and spectrally resolved optical detection is carried out by the detector device (1) and the respective capillary refill behavior is spatially and temporally determined at a time t2 up to which at least one first threshold value of the measurement values detected simultaneously with spatial resolution has reached the measurement value that had been optically detected before the start of the pressure effect.

A system for measuring capillary refill time includes a wearable device and a control unit. The wearable device includes a force sensor to obtain a force signal and an optical sensor to obtain an optical signal. The system ensures that an applied force is acceptable in both magnitude and duration, and that a duration over which the applied force is released or removed is acceptable. These factors can establish that a capillary refill time determined or calculated therein is accurate. The system can also determine the capillary refill time based on the force and optical signals obtained by the force and optical sensors, respectively.