Systems, methods, and interfaces are described herein for noninvasively determining an optimal coronary sinus branch to cannulate for a medical electrical lead. One exemplary method involves applying an electrode apparatus having a plurality of electrodes to a torso of a patient. One of a right ventricular (RV) lead is introduced to a right ventricle or a right atrial (RA) lead is introduced to a right atrium. Noninvasively ultrasonic energy is introduced to a target tissue selected from a set of target tissues. In response to delivering ultrasonic energy to the cardiac tissue, a processing unit receives a torso-surface potential signal from each of a plurality of electrodes distributed on a torso of a patient for the target tissue. Signals are sensed from one of the RA lead and the RV lead in response to delivering ultrasonic energy. For at least a subset of the plurality of electrodes, calculating, with the processing unit, a torso-surface activation time based on the signal sensed from the electrode. Determining whether the tissue site or the another tissue site provides optimal cardiac resynchronization.

It is disclosed an apparatus for restoring voluntary control of locomotion in a subject suffering from a neuromotor impairment comprising a multidirectional trunk support system and a device for epidural electrical stimulation. The robotic interface is capable of evaluating, enabling and training motor pattern generation and balance across a variety of natural walking behaviors in subjects with neuromotor impairments. Optionally, pharmacological cocktails can be administered to enhance rehabilitation results. It is also disclosed a method for the evaluation, enablement and training of a subject suffering from neuromotor impairments by combining robotically assisted evaluation tools with sophisticated neurobiomechanical and statistical analyses. A method for the rehabilitation (by this term also comprising restoring voluntary control of locomotion) of a subject suffering from a neuromotor impairment in particular partial or total paralysis of limbs, is also disclosed.

A system and method is provided for measuring a mechanical property of a biological tube. The system and method operate to arrange a plurality of piezoelectric elements about the biological tube and apply a predetermined force or transduce an endogeneous or exogeneous force to the biological tube. The system and method also operate to receive a respective signal from each piezoelectric element in the plurality of piezoelectric elements responsive to the application of the predetermined force or a transduced endogenous or exogeneous force and calculate the mechanical property of the biological tube based on the signals received from the plurality of piezoelectric elements.

Disclosed embodiments relate to apparatuses and methods for a skin perfusion pressure determination device. In some embodiments, a skin perfusion pressure determination device can include a sensor module including a first sensor for sensing a first parameter associated with a pressure exerted on a target area by the sensor module and a second sensor for sensing a second parameter associated with an amount of blood perfusion at the target area, wherein the first sensor and the second sensor are arranged such that, when the sensor module is pressed against the target area the first sensor produces an output corresponding to the sensed first parameter and the second sensor produces an output corresponding to the sensed second parameter, a proximal end assembly configured to contact the target area, a display to provide feedback of the pressure exerted on a target area and/or the amount of blood perfusion at the target area, and a communication device for providing data transfer from the skin perfusion pressure determination device to a control unit.

This disclosure proposes a technique for finding and treating areas of tooth decay primarily below the gum line using protuberances provided in a length of modified dental floss. The length of modified dental floss is provided with protuberances which can be used to detect areas of tooth decay by the roughness and sensitivity felt as the length of modified dental floss glides over the area of tooth decay. Specially designed posts are used to anchor the ends of the length of modified dental floss in order to be able to apply greater force during flossing, and free up fingers that would normally have the dental floss wrapped around them, to guide the floss to the right locations for flossing.

A wireless pressure ulcer alert dressing system for warning a patient or caregiver that soft tissue pressure or health condition has exceeded some predetermined level that over time would necessitate moving the patient to prevent or at least reduce a risk of soft tissue damage. The dressing assembly is adapted to be applied to or near a surface of the patient's body and generate electrical outputs corresponding to soft tissue pressure and other health characteristics sensed at the surface. The dressing assembly generates output signals based on the electrical outputs and corresponding to whether or not the soft tissue pressure has exceeded a predetermined pressure level during the preselected time period. The dressing assembly includes a pocket formed therein for removable, secured and protected insertion of a variety of different sensors such as multiple pressure sensors.

A system is configured for receiving force data including at least one value indicating the amount of the force applied to the portion of the user and at least one value indicating a direction of the force applied to the portion of the user; obtaining mapping data specifying at least one relation between values of force applied to the portion of the user and changes in a functional responsiveness, functional and/or structural integrity, or both the functional responsiveness and the functional and/or structural integrity of the brain at one or more locations in the brain; estimating, based on the mapping data and the force data, an amount of force loading at one or more particular locations in the brain; and generating, based on the estimating, output data representing an amount of the damage to the brain at the one or more particular locations in the brain.

The invention relates to a system for predicting the viability of a body tissue in a patient. The system comprises a computing device, and a first pressure measuring device for measuring local perfusion pressure in the body tissue of the patient. This measuring device is connected to the computing device. A second pressure measuring device is provided for measuring the systemic perfusion pressure of the patient, said second pressure measuring device being connected to the computing device. A feedback indicator is connected to the computing device and is adapted to indicate the viability of the tissue calculated by the computing device on the basis of the measured local and systemic perfusion pressures. The invention also includes a method of predicting the viability of the body tissue and to the first pressure measuring device.

Various systems are disclosed herein for detecting, monitoring, evaluating, and characterizing pain. They systems include a number of connected components, such as a provider device, a body-mapping system, a patient device, a user device, a referred pain device and/or a rectal probe device. Accordingly, the systems allow providers to track location-specific pain intensity for any number of patients over time in order to generate reports and determine treatment recommendations for such patients.

Methods are disclosed for measuring the size of body parts treated by a compression therapy device. Either the volume or circumference of the body part may be measured. The methods may include evacuating an inflatable compression sleeve to a known pressure, inserting the body part into the compression sleeve, inflating the sleeve to a pre-set condition, and then measuring one or more inflation related parameters. The pre-set conditions may include a pre-determined pressure, volume, or size of the inflatable cells comprising the sleeve. The inflation related parameters may include the time to fill the cell to a pre-set pressure, the pressure attained after a pre-set time of inflation, or the measured volume of a cell after a pre-set amount of air is introduced into it. The methods may also include deflating the cells from the known inflation state to a second inflation state and measuring similar parameters.