Compositions and methods for assessing blood vessels and organs of the body are disclosed herein, specifically methods for assessing the vasculature of the eye.

Offset illumination using multiple emitters in a fluorescence imaging system is described. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The emitter comprises a first emitter and a second emitter for emitting different wavelengths of electromagnetic radiation. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises one or more of a hyperspectral emission, a fluorescence emission, and/or a laser mapping pattern.

A plurality of devices that provide examination/diagnosis and/or treatment benefits to a patient are presented. The device including a plurality of light sources that provide for the emission of light in a plurality of wavelength ranges, wherein the plurality of light sources are activated by a sensor, configured to determine a proximity of the device to a patient, to control an application of a voltage to selected one of the plurality of light sources for a predetermined time period.

Embodiments related to medical imaging devices including rigid imaging tips and their methods of use for identifying abnormal tissue within a surgical bed are disclosed.

This invention is a programmable, mobile, and reusable point-of-care-testing (POCT) unit for identifying pathogens and their viability state in the respiratory airways realis tempus. The device can be used to test for COVID-19 infections in individuals entering or exiting venues (i.e. schools, restaurants, bars, sporting events, etc.). The POCT unit is capable of performing thousands of tests without maintenance or repair. The POCT unit employs fluoresced spectra analysis (FSA) to uniquely identify the specific bacteria or virus and their relative concentration level based on spectral pattern recognition. Additionally, the POCT unit identifies the living or dead state of bacteria or the active or inactive state of a virus. Automatic pattern recognition of the bacteria or virus spectrum is done using Artificial Intelligence (AI) Deep Learning Neural Networks (DLNN). The DLNN computational process is performed at a remote site linked to the POCT unit by a smartphone or lap-top online connection. The POCT unit is an “at patient” testing instrument for identifying pathogen including SARS-CoV2, SWINE-FLU, H1N1, E-BOLI, Influenza, etc. The POCT unit response time is driven by the SmartPhone connectivity time or the laptop computational ability. The identification of a specific pathogen is determined by the programming of the DLNN and therefore useable for identifying current and future respiratory bacterial or viral infections by adjusting the DLNN software using new training data. The POCT unit has three configurations, namely, a mobile unit connected by Smartphone or PC and a personal home user version connected through Bluetooth to a SmartPhone.

An imaging device and a method of imaging accurately decides a cause when pixel values of each pixel in a predetermined region of a fluorescence image varies with time. The imaging device, has an excitation light source, an imaging element that acquires a fluorescence image, an image storing element that stores the fluorescence image with time, a pixel value measurement element an average value calculation element and a first curve generation element that generates showing a time-course change of the average pixel value of the entire fluorescence image, a second curve generation element that generates showing a time-course change of the average pixel value of the region of interest.

The imaging apparatus includes: a first light source; a second light source; a reference scale disposed in close proximity to a subject; a first imaging unit for capturing a visible image; a second imaging unit for capturing a fluorescence image; an image display unit for displaying a visible image and a fluorescence image; an operation unit which is a user interface for inputting a desired measurement line on the fluorescence image; and a distance calculation unit for calculating a length of the measurement line based on a length of the reference scale, and the image display unit displays a length of the measurement line calculated by the distance calculation unit.

A medical endoscope that has a reusable portion to which either of two different single-use portions can be snapped in by hand to thereby form two different assembled endoscopes. When one of the single-use portions is assembled with the reusable portion, a motor in the reusable portion robotically rotates a cannula about a proximal end of the single use portion. When the other single-use portion is assembled with the reusable portion, the motor robotically angulates the distal end of the cannula. Another medical endoscope is single-use in its entirety and has motor-driven angulation of the cannula's distal end. Another has manually controlled angulation.

An imaging method of a fluorescent image performs image processing before generating colored-fluorescent images, including steps: respectively imaging the red, green and blue lights of the white light on three monochromatic sensors under the precondition that the software processing speed is not affected; imaging the near infrared fluorescent light on one of the monochromatic sensors; determining whether the sensor used to receive the near infrared fluorescent light receives the fluorescent signal; calculating the light intensity received by the sensor receiving the fluorescent signal and the light intensities received by the other two sensors; automatically adjusting the projection intensity of the white light source and/or the excitation light source according to the difference of the intensities of the two types of light signals, whereby a closed-loop system is formed to simultaneously present the colored-florescent images on a picture with the best contrast.

Embodiments of apparatuses and methods for determining an emplacement of sensors in a wound dressing are disclosed. In some embodiments, a wound dressing includes a plurality of sensors configured to measure wound or patient characteristics. One or more processors are configured to receive wound or patient characteristics data as well as emplacement data. The received data can be used to determine an emplacement of the plurality of sensors, the wound dressing, or a wound. The sensors can include a set of nanosensors. The wound dressing can include pH sensitive ink which can be utilized for determining a placement of the wound dressing and determining a pH associated with the wound. The wound dressing can be used in a negative pressure wound therapy system.