A processing device for a radiation device is configured to carry out the steps of retrieving, from a data storage, volume data of a subject that was generated by imaging an internal structure of the subject, determining a position of an object in the subject based on the retrieved volume data of the subject, obtaining geometry information including a position of a radiation source and a position of a radiation detector, and obtaining a direction of the radiation detector, and determining a condition for imaging with the radiation source, so that the object can be captured through the imaging, based on the volume data, the position of the object, the position of the radiation source, the position of the radiation detector, and the direction of the radiation detector.

A storage unit stores volume data including a blood vessel region. An extracting unit extracts the blood vessel region from the volume data. A specifying unit specifies a position of a region of interest in the blood vessel region and a deflection direction of a blood vessel region included in the region of interest. A determining unit determines a viewing position and a viewing direction based on the position of the region of interest and the deflection direction. A generating unit generates image data concerning the viewing position and the viewing direction based on the volume data. A display unit displays an image represented by the image data.

The present invention relates to a medical method of managing a cerebrovascular insult, the method comprising the following steps in this order: a) placing a patient on a patient support unit; b) positioning a mobile tomographic imaging system in a predetermined position relative to the patient support unit with the patient placed on the patient support unit; c) imaging at least part of the patient's brain using an imaging unit of the tomographic imaging system, the imaging comprising in particular generating an image describing the functioning of the patient's blood vessel system; d) determining, in dependence on the result of the imaging, whether the patient support unit should be rotated relative to the tomographic imaging system with the patient placed on the patient support unit so that the patient is free of the imaging unit in order to conduct a medical intervention on the patient's blood vessel system, or whether the patient support unit may remain in its position relative to the tomographic imaging system with the patient placed on the patient support unit.

A device and a method to measure the concentrations of oxygenated and deoxygenated hemoglobin in tissue around a tumor via near-infrared (NIR) spectroscopy with a photonic mixer device (PMD) is described.

The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a ligand that binds to the active site of carbonic anhydrase, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid, amide, ureido, or polyethylene glycol derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.

A breast diffusion optical tomography (DOT) device includes a light source, a detector, a mechanical driver and a contour acquisitor without using optical fiber and reduce the system complexity. The light source includes M1 number of multi-wavelength near-infrared light emitters for a continuous-wave mode and M2 number of laser diodes of different wavelengths for a frequency-domain mode. The detector includes N1 number of silicon photomultipliers for detecting near-infrared light in the continuous-wave mode and N2 number of silicon photomultipliers for detecting near-infrared light in the frequency-domain mode. The mechanical driver adjusts a distance between the light source and the detector. The contour acquisitor obtains the geometry of a patient's breast for reconstruction. The DOT device uses amplitude and phase information obtained in the frequency-domain mode to estimate initial optical parameters of tissues and then apply for reconstruction in the continuous-wave mode.

Systems and methods are provided in which local tissue diagnostic measurements are correlated with archival local tissue diagnostic data from prior tissue analyses to supplement diagnostic measurements with tissue analysis data from prior tissue analyses having similar local tissue diagnostic data. The tissue analysis data may include information such as pathology data, outcome data, and diagnosis data. The archived local tissue diagnostic data and the tissue analysis data may be stored in a database, and employed for a wide variety of methods, involving preoperative, intraoperative, and/or postoperative phases of a medical procedure. Methods and systems are also provided for displaying, on a medical image shown in a user interface, hyperlinked reference markers associated with tissue analyses, where the reference markers are shown at locations corresponding to local tissue analyses, and where associated diagnostic data and/or tissue analysis may be viewed by selecting a given reference marker.

One or more devices, systems, methods, and storage mediums for optical imaging medical devices, such as, but not limited to, Optical Coherence Tomography (OCT), single mode OCT, and/or multi-modal OCT apparatuses and systems, and methods and storage mediums for use with same, for triggering auto-pullback, including for devices or systems using blood clearing, are provided herein. Examples of applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments, such as, but not limited to, optical probes, catheters, capsules and needles (e.g., a biopsy needle). Techniques provided herein also improve processing and imaging efficiency while achieving images that are more precise.

A dual modality imaging apparatus, comprising a magnetic resonance imaging (=MRI) system and a fluorescence molecular tomography (=FMT) system, for investigating a sample (42) located at a sample position (10), wherein the MRI system comprises a magnet (9) with a room temperature bore (8), with the sample position (10) located within the bore (8), and wherein the FMT system comprises means for directing a light beam (12, 17; 30) towards the sample position (10), and a position-sensitive detector (37) for collecting fluorescence light from the sample (42), is characterized in that the position-sensitive detector (37) is located within the bore (8), wherein at least part of the sample (42) is imaged onto the position-sensitive detector (37), and that the means for directing the light beam (12, 17; 30) comprise a focusing device for focusing the light beam (12, 17; 30) into a focal spot (41) on the sample (42), and a scanning device for scanning the focal spot (41) on the sample (42). The apparatus is simple in design and versatile in application, and in particular imposes less limitations on the maximum number of source/detector pairs during FMT imaging, thus allowing a better FMT image resolution.

Provided are methods of determining if an individual is a responder to treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof. Also provided are methods for selecting an individual for treatment with (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine or a pharmaceutically acceptable salt, solvate or hydrate thereof from a plurality of individuals in need of weight management. Also provided are methods for weight management in an individual in need thereof. Also provided are compounds, compositions, and kits for use in a method of weight management in an individual.