Described herein are methods and antibodies useful for reducing, eliminating, or preventing infection with a viral population in an animal. Also described herein are antigens useful for targeting by heavy chain antibodies and VHH fragments for reducing a viral population in an animal.

A coat protein of Junonia coenia densovirus (JcDNV) is used to deliver attached peptide insect toxin across the gut epithelium of a fall armyworm, Spodoptera frugiperda. A fusion protein comprising VP4 attached to an insect toxin via a peptide linker is developed. A composition comprising a JcDNV coat protein attached to an insect toxin via a peptide linker can be used for insect pest control.

A coat protein of Junonia coenia densovirus (JcDNV) is used to deliver attached peptide insect toxin across the gut epithelium of a fall armyworm, Spodoptera frugiperda. A fusion protein comprising VP4 attached to an insect toxin via a peptide linker is developed. A composition comprising a JcDNV coat protein attached to an insect toxin via a peptide linker can be used for insect pest control.

Methods and compositions are provided that can be used to modify the assembly activating protein (AAP)-dependence of an adeno-associated virus (AAV).

Methods and compositions are provided that can be used to modify the assembly activating protein (AAP)-dependence of an adeno-associated virus (AAV).

Disclosed herein are chimeric recombinant adeno-associated virus (rAAV) capsid proteins comprising a region of VP1μ that is replaced by the corresponding amino acids of the VP1μ of AAV serotype 1 (AAV1) or AAV serotype 8 (AAV8), and particles comprising them.

Disclosed herein are chimeric recombinant adeno-associated virus (rAAV) capsid proteins comprising a region of VP1μ that is replaced by the corresponding amino acids of the VP1μ of AAV serotype 1 (AAV1) or AAV serotype 8 (AAV8), and particles comprising them.

The present disclosure provides AAV variants that exhibit a preference for retrograde movement in neurons and methods of using such variants.

The present disclosure provides AAV variants that exhibit a preference for retrograde movement in neurons and methods of using such variants.

The invention relates to synthetic adeno-associated virus capsids targeted to the liver and vims vectors comprising the same. The invention further relates to methods of using the vectors to target the liver and provide liver-specific expression, as well as transduce human primary hepatocytes and cell lines.