An end stage renal disease (ESRD) monitoring system may include an implantable sensor and a reader device with an optical sensor. The implantable sensor may be configured to detect a group of analytes relevant to ESRD, such as glucose, creatinine, urea, and potassium. The implantable sensor may be implanted into the dermis of an animal, and may exhibit color changes in response to the presence of the target analytes or reaction product(s) thereof. The reader device may be configured to capture an image of the implanted sensor and to determine the concentration of the target analytes based at least in part on the image. The reader device may be a personal electronic device such as a cell phone, PDA, or personal computer.

A surgical system configured for treating tissue is provided. The surgical system includes a laser source and a laser scalpel. The laser scalpel is adapted to couple to the laser source and is operable in two modes of operation, a first mode of operation to analyze tissue of interest and a second mode of operation to treat tissue of interest. The laser scalpel includes a housing having first and second fiber optic cables extending therethrough. Each of the first and second fiber optic cables operable under the first mode of operation to collect information pertaining to at least one optical property of tissue of interest and at least one of the first and second fiber optic cables also operable under the second mode of operation to treat the tissue of interest.

Methods and systems useful for machine learning assisted imaging and detection of peripheral nerves comprising reflectance imaging spectroscopy. The method can be conducted label-free and in real-time.

A method and user device for determining a unified Parkinson's disease rating scale (UPDRS) value associated with a user of the user device include obtaining video data associated with a movement of a body part of the user. The UPDRS value is determined using a model and the video data associated with the movement of the body part of the user. The UPDRS value is provided to permit an evaluation of the user based on the UPDRS value.

Exemplary embodiments of the present disclosure include apparatus and methods to identify endometrial tissue.

Some embodiments of the present disclosure are directed to ultraweak photon emission imaging systems and methods. In some embodiments, a method comprises acquiring an ultraweak photon emission image of a target area of a patient for detection of a pathological condition; wherein the target area comprises an area of interest and a portion surrounding the area of interest, wherein acquiring the image comprises: enhancing formation of reactive oxygen species and/or reactive nitrogen species in the target area, wherein enhancing formation of the reactive oxygen species and/or the reactive nitrogen species comprises applying low level light illumination to the target area from 1 second to 60 minutes so as to achieve a total power output from 1 mW to 10,000 W using an average power density from 0.1 W/cm.sup.2 to 1 W/cm.sup.2; and imaging the target area, wherein imaging the target area comprises a total exposure time from 1 second to 60 minutes.

Method, system and apparatus (10) for capturing eye/pupil movement(s). Wearable apparatus (10) includes image capture means (12,18), a light source (16) to illuminate the eye(s). Video recordings can be stored in memory (20) and/or transmitted to a remote location. The apparatus (10) can include on-board image processing. Pupil shape and/or position can be determined e.g. from glints (28). Direction and speed of eye motion can be determined. Head movement (50) and eye motion (52) measurements can be obtained. Measurement by head movement sensors (32), body sensors (34) and/or environment sensors (38) (e.g. gravity) can be factored in to an assessment of the user's condition.

The present invention relates generally to a means of detecting a target molecule, compound or substance through the attractive forces occurring between said target and a target-specific molecular probe whereby said molecular probe expresses a selective high affinity for target and is capable of fluorescent luminescence at a definitive frequency and in a determinable light wave range. Specifically, said molecular probe offers target-specific binding where a resultant duplex molecule fluoresces upon hybridization to a target's unique molecule nucleotide sequence. Said hybridization allows for optical detection of said duplex via a directed, filtered and focused light source which makes said duplex both quantifiable and quantifiable via luminescence (i.e., light wave excitation) and subsequent photo detection utilizing ellipsoidal reflection to amplify detection and measurement improving both sensitivity and specificity.

The invention pertains to the establishment, implementation and management of a personalized information system pertinent to a user's general health, wellness and/or sport performance. Disclosed is a system capable of transcutaneous measurement of a subject including at least one light source, at least one light detector, and at least one component for generating or storing at least one value of VC02 or at least one value of V02 from the detected signal. Further, disclosed is a portable device for analyzing the composition of the respired gasses of a subject including at least one air flow conduit through which the subject can inspire or expire air through the body of the device, at least one sampling portal, an oxygen sensor, and at least one flow sensor. A dual-battery system is also provided by which an uninterrupted power supply can be provided for electronic components.

Systems, methods and devices are implemented for microscope imaging solutions. One embodiment of the present disclosure is directed toward an epifluorescence microscope. The microscope includes an image capture circuit including an array of optical sensor. An optical arrangement is configured to direct excitation light of less than about 1 mW to a target object in a field of view of that is at least 0.5 mm.sup.2 and to direct epi-fluorescence emission caused by the excitation light to the array of optical sensors. The optical arrangement and array of optical sensors are each sufficiently close to the target object to provide at least 2.5 μm resolution for an image of the field of view.