A method of detecting injury to the brain such as stroke, concussion and cognitive dysfunction using a contrast agent and light source. The blood ocular barrier is disrupted when said injury occurs, allowing the entry of contrast agent into the aqueous and vitreous humor. An exemplary method comprises injecting a contrast agent into a peripheral location and then testing for leakage of contrast agent into the eye cavity by observing for light reflection, when a beam of light incidents on the contrast agent in the eye.

A control device for a vehicle for determining perceptual load of a visual and dynamic driving scene, the control device being configured to: receive an image sequence representing the driving scene, extract a set of scene features from the image sequence, the set of scene features representing static and/or dynamic information of the driving scene, calculate a time-aggregated representation of the image sequence based on the extracted set of scene features, calculate an attention map of the driving scene by attentional pooling of the time-aggregated representation of the image sequence, and determine the perceptual load of the driving scene based on the attention map. The invention further relates to a corresponding method.

The present invention discloses a device for acquiring a functional image of tissue and a method for acquiring a functional image by using same, the device comprising: a light source for irradiating a tissue to be imaged with coherent light; an image acquisition unit for acquiring an image of a speckle pattern which is formed by scattering the light emitted from the light source over the tissue, and acquiring multiple images having different exposure times; an image processing unit for generating a functional image of the tissue on the basis of the multiple images acquired by the image acquisition unit; and a control unit for adjusting the light quantity of the light emitted to the tissue such that the multiple images having different exposure times have brightness values in a common range, and controlling the operation of the image acquisition unit.

The present invention relates to a real-time parathyroid imaging apparatus including: a light source including an excitation filter capable of exciting parathyroid glands; and a camera including an image sensor and an emission filter of which a transmissivity ratio between a visible light region and a near-infrared emission wavelength region is N:1 (here, N<1). Through the present invention, a system may be implemented whereby a surgeon may acquire, in real-time during an operation, an autofluorescence image of the parathyroid glands by using a near-infrared light source, and an auto focus function may be used, and visible light and near-infrared autofluorescence images may be simultaneously fused and acquired without having to turn off the lights in an operating room.

Instruments and methods for wide-field polarized imaging of the skin to determine an outer lesion margin objectively in vivo to provide guidance to a surgeon. Quantitative characterization of collagen structures in the skin can be used to determine the outer lesion margin or monitor skin treatment.

A wearable device includes a housing with a window and an electronic module supported by the housing. The electronic module includes a photoplethysmography sensor, a motion sensor, and a signal processor that processes signals from the motion sensor and signals from the photoplethysmography sensor. The signal processor is configured to remove frequency bands from the photoplethysmography sensor signals that are outside of a range of interest using a band-pass filter to produce pre-conditioned signals, and to further process the pre-conditioned signals using the motion sensor signals to reduce motion artifacts from footsteps during subject running. The device includes non-air light transmissive material in optical communication with the photoplethysmography sensor and the window that serves as a light guide for the photoplethysmography sensor. The window optically exposes the photoplethysmography sensor to a body of a subject wearing the device via the non-air light transmissive material.

A method for evaluating a gastrointestinal tract may include characterizing one or more disease parameters using objective measures obtained from imaging data of a gastrointestinal tract. The one or more disease parameters reflect a measure of at least one of lesions, ulcers, bleeding, stenosis, and vasculature. The method may also include using the one or more characterized disease parameters to classify a disease state.

A measurement probe for preschoolers includes a fiber configured to irradiate a head of a subject with light, and a holder made of a metal or resin other than rubber. A tip surface of a tip of the fiber that contacts the head of the subject is flat, and a corner of a tip surface of the holder that contacts the head of the subject is chamfered.

Techniques are described for non-invasive, cuff-less measurement of blood pressure of a user using a portable electronic device. Illumination is projected through a body part and received by photodetectors on the other side of the body part. The body part includes elastic pathways of the circulatory system through which blood flows. Cycles of contraction and relaxation by the heart cause pulse waves to travel through the blood, which cause volumetric changes in the elastic pathways. The transient changes in blood volume result in corresponding transient changes in the amount of illumination that is absorbed by the body part versus the amount that passes through to the photodetectors, as manifest by a detection output signal. Calibration data can be used to convert the detection output signal to blood pressure measurements, such as including diastolic and systolic blood pressure readings.

Systems and methods of optical transcutaneous oxygenation monitoring. The oxygenation monitor comprises a photoluminescent oxygen-sensitive probe, a photon source positioned to direct photons at the probe, a photodetector positioned to detect light emitted from the probe when the photon source directs photons at the probe, a controller in electrical communication with the photon source and the photodetector, the controller being configured to execute a program stored in the controller to calculate a level of oxygen adjacent the probe from an electrical signal received from the photodetector. The photon source, the photodetector, and the controller are disposed in or on a support structure.