Patent classifications
C07K14/26
Proteins and nucleic acids useful in vaccines targeting <i>Klebsiella pneumoniae</i>
The present invention relates to proteins and nucleic acids derived from Klebsiella pneumoniae as well as therapeutic and diagnostic uses of the proteins and nucleic acids.
Proteins and nucleic acids useful in vaccines targeting <i>Klebsiella pneumoniae</i>
The present invention relates to proteins and nucleic acids derived from Klebsiella pneumoniae as well as therapeutic and diagnostic uses of the proteins and nucleic acids.
CHIMERIC KLEBICINS
The present invention provides chimeric klebicins by combining translocation, receptor-binding, and bactericidal domains originated from different klebicins to achieve improved target cell range and bactericidal activity. Also provided are related compositions, kits, and methods of use of these chimeric klebicins.
CHIMERIC KLEBICINS
The present invention provides chimeric klebicins by combining translocation, receptor-binding, and bactericidal domains originated from different klebicins to achieve improved target cell range and bactericidal activity. Also provided are related compositions, kits, and methods of use of these chimeric klebicins.
CONTROL OF NITROGEN FIXATION IN RHIZOBIA THAT ASSOCIATE WITH CEREALS
Disclosed herein are engineered rhizobia having nif clusters that enable the fixation of nitrogen under free-living conditions, as well as ammonium and oxygen tolerant nitrogen fixation under free-living conditions. Also provided are methods for producing nitrogen for consumption by a cereal crop using these engineered rhizobia.
BINDING MOIETIES FOR BIOFILM REMEDIATION
Binding agents able to disrupt bacterial biofilms of diverse origin are described, including monoclonal antibodies secreted by human B lymphocytes. Methods to prevent formation of or to dissolve biofilms with these binding agents are also described. Immunogens for eliciting antibodies to disrupt biofilms are also described.
PROTEINS INCREASING PANCREATIC BETA CELL NUMBER AND METHODS OF USE
Methods of identifying compounds that increase cell number and/or proliferation by determining the effect of compounds on cell number or proliferation in zebrafish pancreas are provided.
PROTEINS INCREASING PANCREATIC BETA CELL NUMBER AND METHODS OF USE
Methods of identifying compounds that increase cell number and/or proliferation by determining the effect of compounds on cell number or proliferation in zebrafish pancreas are provided.
Synthetic gene clusters
Methods for making synthetic gene clusters are described.
Synthetic gene clusters
Methods for making synthetic gene clusters are described.