A61B5/0205

Precision treatment platform enabled by whole body digital twin technology

A patient health management platform accesses a metabolic profile for a patient and biosignals recorded for the patient during a current time period comprising sensor data and/or lab test data collected for the patient. The platform receives patient data recorded during the current time period comprising food items consumed, medications taken, and symptoms experienced by the patient. The platform implements a machine-learned metabolic model to determine a metabolic state of the patient at a conclusion of the current time period by comparing a true representation of the metabolic state and a prediction of the metabolic state. The true representation and the prediction are determined based on the recorded biosignals and the recorded patient data, respectively. The platform generates a patient-specific treatment recommendation outlining instructions for the patient to improve their metabolic state and provides the patient-specific treatment recommendation to the patient device for display to the patient.

Patient-Assisted Alarm System

In the present invention, a system and associated method is provided for monitoring vital parameters of a patient. The monitoring system includes sensors disposed on the patient and operably connected to a monitor. The parameters that are sensed by the sensors are transmitted to the monitor and compared with alarm thresholds and operational criteria stored within the monitor. When an alarm condition is sensed by the system, the system can actively solicit patient assistance in the confirmation of the alarm condition based on a set of reactive inputs stored within the system to enable medical personnel to appropriately respond to clinically relevant sensed alarm condition(s).

SYSTEMS AND METHODS TO DETERMINE SURROGATES OF BLOOD PRESSURE

Embodiments of the present disclosure relate to systems and methods for determining a subject's blood pressure using one or more implantable medical devices (IMDs). In an embodiment, a medical system comprises: at least one implantable medical device configured to sense signals associated with heart sounds of a subject and a processing unit communicatively coupled to the at least one implantable medical device. The processing unit is configured to: receive heart sound signals corresponding to the signals associated with the heart sounds; and calculate a surrogate of the subject's blood pressure using at least one heart sound signal of the received heart sound signals.

SYSTEMS AND METHODS TO DETERMINE SURROGATES OF BLOOD PRESSURE

Embodiments of the present disclosure relate to systems and methods for determining a subject's blood pressure using one or more implantable medical devices (IMDs). In an embodiment, a medical system comprises: at least one implantable medical device configured to sense signals associated with heart sounds of a subject and a processing unit communicatively coupled to the at least one implantable medical device. The processing unit is configured to: receive heart sound signals corresponding to the signals associated with the heart sounds; and calculate a surrogate of the subject's blood pressure using at least one heart sound signal of the received heart sound signals.

Apparatus, system, and method for physiological sensing in vehicles

Methods and apparatus provide physiological movement detection, such as gesture, breathing, cardiac and/or gross motion, such as with sound, radio frequency and/or infrared generation, by electronic devices such as vehicular processing devices. The electronic device in a vehicle may, for example, be any of an audio entertainment system, a vehicle navigation system, and a semi-autonomous or autonomous vehicle operations control system. One or more processors of the device, may detect physiological movement by controlling producing sensing signal(s) in a cabin of a vehicle housing the electronic device. The processor(s) control sensing, with a sensor, reflected signal(s) from the cabin. The processor(s) derive a physiological movement signal with the sensing signal and reflected signal and generate an output based on an evaluation of the derived physiological movement signal. The output may control operations or provide an input to any of the entertainment system, navigation system, and vehicle operations control system.

Apparatus, system, and method for physiological sensing in vehicles

Methods and apparatus provide physiological movement detection, such as gesture, breathing, cardiac and/or gross motion, such as with sound, radio frequency and/or infrared generation, by electronic devices such as vehicular processing devices. The electronic device in a vehicle may, for example, be any of an audio entertainment system, a vehicle navigation system, and a semi-autonomous or autonomous vehicle operations control system. One or more processors of the device, may detect physiological movement by controlling producing sensing signal(s) in a cabin of a vehicle housing the electronic device. The processor(s) control sensing, with a sensor, reflected signal(s) from the cabin. The processor(s) derive a physiological movement signal with the sensing signal and reflected signal and generate an output based on an evaluation of the derived physiological movement signal. The output may control operations or provide an input to any of the entertainment system, navigation system, and vehicle operations control system.

REMOTE PATIENT MONITORING AND MEDICATION DELIVERY SYSTEM
20180008360 · 2018-01-11 ·

The present invention relates to systems and methods for remotely monitoring the health of a patient in a real-time, continuous manner, remotely deliver therapeutic medications to the patient, and facilitating communication between the patient and a remotely located patient care provider.

MINUTE VOLUME SENSOR OPTIMIZATION USING QUADRIPOLAR LEADS

An apparatus comprises a respiration sensing circuit configured for coupling electrically to a plurality of electrodes and for sensing a respiration signal representative of respiration of a subject; a signal processing circuit electrically coupled to the respiration sensing circuit and configured to extract a respiration parameter from a sensed respiration signal and determine a signal performance metric for the sensed respiration signal using the respiration parameter; and a control circuit. The control circuit is configured to: initiate sensing of a plurality of respiration signals using different electrode combinations of the plurality of electrodes and determining of the signal performance metric for the sensed respiration signals; and enable an electrode combination from the plurality of electrodes and for use in monitoring respiration of the subject according to the signal performance metric.

MINUTE VOLUME SENSOR OPTIMIZATION USING QUADRIPOLAR LEADS

An apparatus comprises a respiration sensing circuit configured for coupling electrically to a plurality of electrodes and for sensing a respiration signal representative of respiration of a subject; a signal processing circuit electrically coupled to the respiration sensing circuit and configured to extract a respiration parameter from a sensed respiration signal and determine a signal performance metric for the sensed respiration signal using the respiration parameter; and a control circuit. The control circuit is configured to: initiate sensing of a plurality of respiration signals using different electrode combinations of the plurality of electrodes and determining of the signal performance metric for the sensed respiration signals; and enable an electrode combination from the plurality of electrodes and for use in monitoring respiration of the subject according to the signal performance metric.

DUAL EEG NON-CONTACT MONITOR WITH PERSONAL EEG MONITOR FOR CONCURRENT BRAIN MONITORING AND COMMUNICATION
20180008145 · 2018-01-11 · ·

Aspects of the disclosure can provide a method and device for detecting EEG signals of a first person in proximity to the device. The device can include a non-contact EEG directional circuit having non-contact sensors, the non-contact EEG directional circuit being configured to detect the EEG signals produced by a brain of the first person without making contact with the first person. The device can further include a processor coupled to the non-contact EEG directional circuit that is configured to analyze the EEG signals to detect patterns in the EEG signals that correspond to a state of the first person in proximity to the non-contacting sensor and feedback device that is configured to provide a second person with an indication of the state of the first person in proximity to the non-contacting sensor. Additionally, the device can include a contact EEG circuit having sensors that are in contact with the second person and that is configured to detect second EEG signals produced by a brain of the second person, wherein the processor is coupled to the contact EEG circuit and is configured to analyze the second EEG signals to detect patterns in the second EEG signals that correspond to a state of second the person.