The disclosure provides a measurement circuit. The measurement circuit includes a control engine. An excitation source is coupled to the control engine. A first set of electrodes and a second set of electrodes are coupled to the excitation source and receive current from the excitation source. The control engine operates the excitation source in a first mode and a second mode. The control engine, in the first mode, measures a parasitic impedance associated with the first and the second set of electrodes, and the control engine, in the second mode, measures an impedance of the first and the second set of electrodes and of an external object.

The present disclosure provides systems and methods for predicting a disease state of a subject using ultrasound imaging and ancillary information to the ultrasound imaging. At least two quantitative measurements of a subject, including at least one measurement taken using ultrasound imaging, as part of quantified information can be identified. One of the quantitative measurements can be compared to a first predetermined standard, included as part of ancillary information to the quantified information, in order to identify a first initial value. Further, another of the quantitative measurements can be compared to a second predetermined standard, included as part of the ancillary information, in order to identify a second initial value. Subsequently, the quantitative information can be correlated with the ancillary information using the first initial value and the second initial value to determine a final value that is predictive of a disease state of the subject.

The present disclosure provides systems and methods for predicting a disease state of a subject using ultrasound imaging and ancillary information to the ultrasound imaging. At least two quantitative measurements of a subject, including at least one measurement taken using ultrasound imaging, as part of quantified information can be identified. One of the quantitative measurements can be compared to a first predetermined standard, included as part of ancillary information to the quantified information, in order to identify a first initial value. Further, another of the quantitative measurements can be compared to a second predetermined standard, included as part of the ancillary information, in order to identify a second initial value. Subsequently, the quantitative information can be correlated with the ancillary information using the first initial value and the second initial value to determine a final value that is predictive of a disease state of the subject.

A method for monitoring a health parameter in a person is disclosed. The method involves transmitting radio waves below the skin surface of a person and across a range of stepped frequencies, receiving radio waves on a two-dimensional array of receive antennas, the received radio waves including a reflected portion of the transmitted radio waves across the range of stepped frequencies, generating data that corresponds to the received radio waves, wherein the data includes amplitude and phase data, deriving data from at least one of the amplitude and phase data, and determining a value that is indicative of a health parameter in the person in response to the derived data.

A system for telemedicine diagnostics through remote sensing includes a computing device configured to initiate a communication interface between the computing device and a client device operated by a human subject, wherein the secure communication interface includes an audiovisual streaming protocol, receive, from at least a remote sensor at the human subject, a plurality of current physiological data, generate a clinical measurement approximation as a function of the change of a first discrete and a second discrete set of current physiological data, wherein generating further comprises receiving approximation training data correlating physiological data with clinical measurement data, training a measurement approximation model as a function of the training data and a machine-learning process, and generating the clinical measurement approximation as a function of the current physiological data and the measurement approximation model, and presenting the clinical measurement approximation to a user of the computing device using the secure communication interface.

A pulse measurement device is provided, including a first signal source, a second signal source, two microwave resonators, two mixers, and a signal processing unit. The first signal source and the second signal source output a first high-frequency signal and a second high-frequency signal, respectively. Each of the microwave resonators generates an electric field according to the first high-frequency signal, and senses a variation in the electric field which is interfered by a pulse to obtain a sensing signal. Each of the mixers is coupled to one of the microwave resonators, to mix the sensing signal and the second high-frequency signal to output a down-converted signal. The signal processing unit respectively demodulates amplitudes of the down-converted signals of the two mixers to obtain amplitude signals.

A PPG PRV device for generating a PRV parameter of a PPG signal (20) as an estimation of a HRV parameter of an ECG signal. The PPG PRV device employs a PPG probe (700) and a PPG PRV controller (710). In operation, the PPG probe (700) generate a PPG signal (20). In response thereto, the PPG PRV controller (710) generates a normalized PPG signal (20′) including a plurality of pulses of the PPG signal (20) designated as normal pulses by the PPG PRV controller (710) and excluding at least one pulse of the PPG signal (20) designated at least one abnormal pulse by the PPG PRV controller (710), wherein the normalized PPG signal (20′) is HRV comparable to the ECG signal. The PPG PRV controller (710) derives the PRV parameter from a HRV measurement of the normalized PPG signal (20′).

A method for uterine activity monitoring may include: acquiring a plurality of signals from a plurality of sensors during uterine activity; processing the plurality of signals to extract a plurality of uterine electrical activity characteristics; analyzing the plurality of uterine electrical activity characteristics; and classifying the uterine activity as one of: a preterm labor contraction, a labor contraction, a Braxton-Hicks contraction, and a state of no contraction. A method of assessing over time a pre-term birth risk of a pregnant female may include: calculating a baseline pre-term birth risk score based on a user input; acquiring, over time, a signal from a sensor; analyzing the signal to extract a parameter of interest, such that the parameter of interest comprises a physiological parameter; and calculating an instant pre-term birth risk score based, at least in part, on the parameter of interest and the user input.

A method for uterine activity monitoring may include: acquiring a plurality of signals from a plurality of sensors during uterine activity; processing the plurality of signals to extract a plurality of uterine electrical activity characteristics; analyzing the plurality of uterine electrical activity characteristics; and classifying the uterine activity as one of: a preterm labor contraction, a labor contraction, a Braxton-Hicks contraction, and a state of no contraction. A method of assessing over time a pre-term birth risk of a pregnant female may include: calculating a baseline pre-term birth risk score based on a user input; acquiring, over time, a signal from a sensor; analyzing the signal to extract a parameter of interest, such that the parameter of interest comprises a physiological parameter; and calculating an instant pre-term birth risk score based, at least in part, on the parameter of interest and the user input.

A sensor apparatus includes at least one substrate layer of an elastically deformable material, the substrate layer extending longitudinally between spaced apart ends thereof. A conductive layer is attached to and extends longitudinally between the spaced apart ends of the at least one substrate layer. The conductive layer includes an electrically conductive material adapted to form a strain gauge having an electrical resistance that varies based on deformation of the conductive layer in at least one direction.