A monitoring system for monitoring a biological subject including a monitoring device having a housing configured to be attached to or supported by an ear of the subject in use, one or more sensors, the one or more sensors including a photoplethysmogram (PPG) sensor provided in the housing and configured to measure attributes of blood flow within the ear, and a monitoring device processor configured to acquire sensors signals from the one or more sensors and generate sensor data at least partially in accordance with signals from the one or more sensors. A transmitter is provided that transmit the sensor data with one or more processing systems receiving the sensor data, analyzing the sensor data and generating a health state indicator indicative of a health state of the subject.

A prosthetic valve comprises a frame assembly having a first opening at an inflow portion of the frame assembly and a second opening at an outflow portion of the frame assembly, a first sensor device situated at the inflow portion of the frame, and a second sensor device situated at the outflow portion of the frame. Each of the first sensor device and the second sensor device is configured to sense a physical parameter and provide a sensor signal. The prosthetic valve further comprises a transmitter assembly configured to receive the sensor signals from the first sensor device and the second sensor device and wirelessly transmit a transmission signal based at least in part on the sensor signals.

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

A medical system for minimally-invasive measurement of blood flow in an artery (AT). An interventional device (IVD) with an optical fiber (FB) comprising a plurality of temperature-sensitive optical sensor segments, e.g. Fiber Bragg Gratings, spatially distributed along its longitudinal extension is configured for insertion into an artery (AT). A temperature changer (TC) is arranged in the WD to introduce a local change in temperature (ΔT) of a bolus of blood in the artery, to allow thermal tracking over time with the optical fiber (FB). A measurement unit (MU) with a laser light source (LS) delivers light to the optical fiber (FB) and receives light reflected from the optical fiber (FB) and generates a corresponding time varying output signal. A first algorithm (A1) translates this time varying output signal into a set of temperatures corresponding to temperatures at respective positions along the optical fiber (FB). A second algorithm (A2) calculates a measure of blood flow (BF) at respective positions along the optical fiber (FB) in accordance with a temporal behavior of said set of temperatures. Such system can be used to quickly scan an artery for diagnosing stenotic regions without the need for pullbacks or injection of toxic liquids. A good spatial resolution of the blood flow measurement can be obtained in real-time.

Systems and methods are disclosed for identifying anatomically relevant blood flow characteristics in a patient. One method includes: receiving, in an electronic storage medium, a patient-specific representation of at least a portion of vasculature of the patient having a lesion at one or more points; receiving values for one or more metrics of interest associated with one or more locations in the vasculature of the patient; receiving one or more observed lumen measurements of the vasculature of the patient; determining the location of a diseased region in the vasculature of the patient using the received values for the one or more metrics of interest, wherein the determination of the location includes predicting or receiving one or more healthy lumen measurements of the vasculature of the patient; determining the extent of the diseased region; and generating a visualization of at least the diseased region.

Systems and methods are disclosed for identifying anatomically relevant blood flow characteristics in a patient. One method includes: receiving, in an electronic storage medium, a patient-specific representation of at least a portion of vasculature of the patient having a lesion at one or more points; receiving values for one or more metrics of interest associated with one or more locations in the vasculature of the patient; receiving one or more observed lumen measurements of the vasculature of the patient; determining the location of a diseased region in the vasculature of the patient using the received values for the one or more metrics of interest, wherein the determination of the location includes predicting or receiving one or more healthy lumen measurements of the vasculature of the patient; determining the extent of the diseased region; and generating a visualization of at least the diseased region.

Provided is a technology capable of accurately measuring biological information with a simple structure. Provided is a biological information measurement device including: a light emitting element that irradiates a living body with light; and a plurality of light receiving elements that receives light scattered in the living body, in which at least one light receiving element has a different area from an area of another light receiving element. Further, provided is a biological information measurement system including: a biological information measurement device including a light emitting element that irradiates a living body with light, and a plurality of light receiving elements that receives light scattered in the living body, in which at least one light receiving element has a different area from an area of another light receiving element; and an analysis device that analyzes biological information on the basis of signals obtained from the light receiving elements.

Provided is a technology capable of accurately measuring biological information with a simple structure. Provided is a biological information measurement device including: a light emitting element that irradiates a living body with light; and a plurality of light receiving elements that receives light scattered in the living body, in which at least one light receiving element has a different area from an area of another light receiving element. Further, provided is a biological information measurement system including: a biological information measurement device including a light emitting element that irradiates a living body with light, and a plurality of light receiving elements that receives light scattered in the living body, in which at least one light receiving element has a different area from an area of another light receiving element; and an analysis device that analyzes biological information on the basis of signals obtained from the light receiving elements.

The present disclosure relates to methods, apparatuses, and systems for generating an arteriosclerosis detection interface. One example method includes obtaining a type of an arteriosclerosis detector in use, generating a detection interface and determining an artery detection position corresponding to the type of the arteriosclerosis detector, and displaying the artery detection position on the detection interface.